Intracerebral hemorrhage as a late complication after CNS treatment of childhood lymphoma
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Intracerebral hemorrhage as a late complication after CNS treatment of childhood lymphoma. / Claviez, A; Neubauer, B; Link, J; Schneppenheim, R.
in: KLIN PADIATR, Jahrgang 210, Nr. 6, 01.01.1999, S. 406-8.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Intracerebral hemorrhage as a late complication after CNS treatment of childhood lymphoma
AU - Claviez, A
AU - Neubauer, B
AU - Link, J
AU - Schneppenheim, R
PY - 1999/1/1
Y1 - 1999/1/1
N2 - Since the majority of children with acute leukemia and lymphoma are long-term survivors, more attention is directed towards late sequelae of therapy. Intracerebral hemorrhage after treatment of central nervous system (CNS) neoplasia in childhood is a very rare event. A seven and a half-year-old boy was admitted to our hospital because of acute third nerve palsy. Three years and eight months before the patient had been treated for a mediastinal T-cell non Hodgkin's lymphoma (T-NHL) with CNS involvement by combined chemo-radiotherapy. Recurrent disease was excluded, but intracerebral hemorrhage in the tectal area was demonstrated by repeated magnetic resonance imaging. Symptoms of incomplete oculomotor paresis improved spontaneously with conservative therapy. Intracerebral hemorrhage may occur as a rare complication in children with malignant CNS disease even years after treatment with combined chemo-radiotherapy.
AB - Since the majority of children with acute leukemia and lymphoma are long-term survivors, more attention is directed towards late sequelae of therapy. Intracerebral hemorrhage after treatment of central nervous system (CNS) neoplasia in childhood is a very rare event. A seven and a half-year-old boy was admitted to our hospital because of acute third nerve palsy. Three years and eight months before the patient had been treated for a mediastinal T-cell non Hodgkin's lymphoma (T-NHL) with CNS involvement by combined chemo-radiotherapy. Recurrent disease was excluded, but intracerebral hemorrhage in the tectal area was demonstrated by repeated magnetic resonance imaging. Symptoms of incomplete oculomotor paresis improved spontaneously with conservative therapy. Intracerebral hemorrhage may occur as a rare complication in children with malignant CNS disease even years after treatment with combined chemo-radiotherapy.
KW - Central Nervous System Neoplasms
KW - Cerebral Hemorrhage
KW - Child
KW - Combined Modality Therapy
KW - Humans
KW - Lymphoma, Non-Hodgkin
KW - Magnetic Resonance Imaging
KW - Male
U2 - 10.1055/s-2008-1043912
DO - 10.1055/s-2008-1043912
M3 - SCORING: Journal article
C2 - 9871896
VL - 210
SP - 406
EP - 408
JO - KLIN PADIATR
JF - KLIN PADIATR
SN - 0300-8630
IS - 6
ER -