Interventricular mechanical dyssynchrony: quantification with velocity-encoded MR imaging
Standard
Interventricular mechanical dyssynchrony: quantification with velocity-encoded MR imaging. / Muellerleile, Kai; Baholli, Loant; Groth, Michael; Barmeyer, Achim A; Koopmann, Katharina; Ventura, Rodolfo; Koester, Ralf; Adam, Gerhard; Willems, Stephan; Lund, Gunnar K.
in: RADIOLOGY, Jahrgang 253, Nr. 2, 2, 11.2009, S. 364-371.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Interventricular mechanical dyssynchrony: quantification with velocity-encoded MR imaging
AU - Muellerleile, Kai
AU - Baholli, Loant
AU - Groth, Michael
AU - Barmeyer, Achim A
AU - Koopmann, Katharina
AU - Ventura, Rodolfo
AU - Koester, Ralf
AU - Adam, Gerhard
AU - Willems, Stephan
AU - Lund, Gunnar K
N1 - (c) RSNA, 2009.
PY - 2009/11
Y1 - 2009/11
N2 - PURPOSE: To evaluate the performance of velocity-encoded (VENC) magnetic resonance (MR) imaging, as compared with pulsed-wave echocardiography (PW-ECHO), in the quantification of interventricular mechanical dyssynchrony (IVMD) as a predictor of response to cardiac resynchronization therapy (CRT).MATERIALS AND METHODS: The study was approved by the local ethics committee, and all patients provided written informed consent. The study involved the examination of 45 patients (nine women, 36 men; median age, 60 years; interquartile age range, 47-69 years) with New York Heart Association class 2.0-3.0 heart failure and a reduced left ventricular ejection fraction (median, 25%; interquartile range, 21%-32%), with (n = 25) or without (n = 20) left bundle branch block. Aortic and pulmonary flow curves were constructed by using VENC MR imaging and PW-ECHO. IVMD was defined as the difference between the onset of aortic flow and the onset of pulmonary flow. Intraclass correlation coefficient, Spearman correlation coefficient, Bland-Altman, and Cohen kappa analyses were used to assess agreement between observers and methods.RESULTS: Inter- and intraobserver agreement regarding VENC MR imaging IVMD measurements was very good (intraclass r = 0.96, P < .001; mean bias, -3 msec +/- 11 [standard deviation] and 0 msec +/- 10, respectively). A strong correlation (Spearman r = 0.92, P < .001) and strong agreement (mean difference, -6 msec +/- 16) were found between VENC MR imaging and PW-ECHO in the quantification of IVMD. Agreement between VENC MR imaging and PW-ECHO in the identification of potential responders to CRT was excellent (Cohen kappa = 0.94).CONCLUSION: VENC MR measurements of IVMD are equivalent to PW-ECHO measurements and can be used to identify potential responders to CRT.
AB - PURPOSE: To evaluate the performance of velocity-encoded (VENC) magnetic resonance (MR) imaging, as compared with pulsed-wave echocardiography (PW-ECHO), in the quantification of interventricular mechanical dyssynchrony (IVMD) as a predictor of response to cardiac resynchronization therapy (CRT).MATERIALS AND METHODS: The study was approved by the local ethics committee, and all patients provided written informed consent. The study involved the examination of 45 patients (nine women, 36 men; median age, 60 years; interquartile age range, 47-69 years) with New York Heart Association class 2.0-3.0 heart failure and a reduced left ventricular ejection fraction (median, 25%; interquartile range, 21%-32%), with (n = 25) or without (n = 20) left bundle branch block. Aortic and pulmonary flow curves were constructed by using VENC MR imaging and PW-ECHO. IVMD was defined as the difference between the onset of aortic flow and the onset of pulmonary flow. Intraclass correlation coefficient, Spearman correlation coefficient, Bland-Altman, and Cohen kappa analyses were used to assess agreement between observers and methods.RESULTS: Inter- and intraobserver agreement regarding VENC MR imaging IVMD measurements was very good (intraclass r = 0.96, P < .001; mean bias, -3 msec +/- 11 [standard deviation] and 0 msec +/- 10, respectively). A strong correlation (Spearman r = 0.92, P < .001) and strong agreement (mean difference, -6 msec +/- 16) were found between VENC MR imaging and PW-ECHO in the quantification of IVMD. Agreement between VENC MR imaging and PW-ECHO in the identification of potential responders to CRT was excellent (Cohen kappa = 0.94).CONCLUSION: VENC MR measurements of IVMD are equivalent to PW-ECHO measurements and can be used to identify potential responders to CRT.
KW - Aged
KW - Aortic Valve
KW - Blood Flow Velocity
KW - Cardiac Pacing, Artificial
KW - Echocardiography
KW - Female
KW - Humans
KW - Magnetic Resonance Imaging/methods
KW - Male
KW - Middle Aged
KW - Observer Variation
KW - Pulmonary Valve
KW - Ventricular Dysfunction, Left/diagnosis
U2 - 10.1148/radiol.2532090145
DO - 10.1148/radiol.2532090145
M3 - SCORING: Journal article
C2 - 19703849
VL - 253
SP - 364
EP - 371
JO - RADIOLOGY
JF - RADIOLOGY
SN - 0033-8419
IS - 2
M1 - 2
ER -