Interobserver variation in grading and staging of squamous cell carcinoma of the penis in relation to the clinical outcome.
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Interobserver variation in grading and staging of squamous cell carcinoma of the penis in relation to the clinical outcome. / Naumann, Carsten M; Alkatout, Ibrahim; Hamann, Moritz F; Al-Najar, Amr; Hegele, Axel; Korda, Joanna Beate; Bolenz, Christian; Klöppel, Günter; Jünemann, Klaus-Peter; van der Horst, Christof.
in: BJU INT, Jahrgang 103, Nr. 12, 12, 2009, S. 1660-1665.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Interobserver variation in grading and staging of squamous cell carcinoma of the penis in relation to the clinical outcome.
AU - Naumann, Carsten M
AU - Alkatout, Ibrahim
AU - Hamann, Moritz F
AU - Al-Najar, Amr
AU - Hegele, Axel
AU - Korda, Joanna Beate
AU - Bolenz, Christian
AU - Klöppel, Günter
AU - Jünemann, Klaus-Peter
AU - van der Horst, Christof
PY - 2009
Y1 - 2009
N2 - OBJECTIVE: To examine interobserver variations in assessing grade and stage of penile squamous cell carcinoma (SCC). PATIENTS AND METHODS: We retrospectively reviewed the pathological features and clinical outcome in 75 patients with SCC of the penis, who were treated in participating urological centres between 1996 and 2005; the assessments of the local pathologists and the review pathologists were compared. RESULTS: There was conformity in tumour grade in 67% and the assessment of tumour stage conformed in 84%; the combination assessment of both grade and stage conformed in 56%. CONCLUSION: Accurate histological subtyping by the surgical pathologist demands standardized guidelines, in particular for histological grading, which is crucial for clinical treatment, but shows significant interobserver variation.
AB - OBJECTIVE: To examine interobserver variations in assessing grade and stage of penile squamous cell carcinoma (SCC). PATIENTS AND METHODS: We retrospectively reviewed the pathological features and clinical outcome in 75 patients with SCC of the penis, who were treated in participating urological centres between 1996 and 2005; the assessments of the local pathologists and the review pathologists were compared. RESULTS: There was conformity in tumour grade in 67% and the assessment of tumour stage conformed in 84%; the combination assessment of both grade and stage conformed in 56%. CONCLUSION: Accurate histological subtyping by the surgical pathologist demands standardized guidelines, in particular for histological grading, which is crucial for clinical treatment, but shows significant interobserver variation.
M3 - SCORING: Zeitschriftenaufsatz
VL - 103
SP - 1660
EP - 1665
JO - BJU INT
JF - BJU INT
SN - 1464-4096
IS - 12
M1 - 12
ER -