Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players

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Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players. / Dalos, D; Marshall, P R; Lissy, M; Maas, K J; Henes, F O; Kaul, M G; Kleinertz, H; Frings, J; Krause, M; Frosch, K H; Welsch, G H.

in: BMC MUSCULOSKEL DIS, Jahrgang 25, Nr. 1, 15.02.2024, S. 144.

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@article{bf698c4eb3e0458b8d2369770e589c40,
title = "Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players",
abstract = "BACKGROUND: Investigation of the association between leg axis alignment and biochemical MRI in young professional soccer players in order to identify a potential influence of the leg axis on cartilage regions at risk.METHODS: Sixteen professional soccer players (21 ± 3 years) underwent static and dynamic leg axis analysis via radiation free DIERS formetric 4 D as well as 3-T MRI examination of both knees. Quantitative T2* mapping of the knee cartilage was performed and T2* values were evaluated as 144 regions of interest. Subgroup analysis was performed in players with severe varus alignment (> 6°).RESULTS: Analysis of the leg axis geometry revealed a mean static alignment of 6.6° ± 2.5 varus and a mean dynamic alignment of 5.1° ± 2.6 varus. Quantitative T2* mapping showed significantly increased T2* values in the superficial cartilage layer compared to the deeper region (p < 0.001) as well as a significant increase in relaxation times in the femoral cartilage from anterior to intermediate to posterior (p < 0.001). Combination of both methods revealed a significant correlation for the degree of varus alignment and the femoral, posterior, deep region of the medial knee compartment (r = 0.4; p = 0.03). If severe varus alignment was present this region showed a significant increase in relaxation time compared to players with a less pronounced leg axis deviation (p = 0.003).CONCLUSION: This study demonstrates that varus alignment in young soccer players is associated with elevated T2* relaxation times in the deep cartilage layer of the medial, posterior, femoral compartment and might therefore be a contributing factor in the early pathogenesis of manifest cartilage lesions. Therefore, these findings should be considered in the development of preventive training programs.",
keywords = "Humans, Soccer, Leg, Cartilage, Articular/diagnostic imaging, Knee Joint/diagnostic imaging, Magnetic Resonance Imaging/methods",
author = "D Dalos and Marshall, {P R} and M Lissy and Maas, {K J} and Henes, {F O} and Kaul, {M G} and H Kleinertz and J Frings and M Krause and Frosch, {K H} and Welsch, {G H}",
note = "{\textcopyright} 2024. The Author(s).",
year = "2024",
month = feb,
day = "15",
doi = "10.1186/s12891-024-07233-3",
language = "English",
volume = "25",
pages = "144",
journal = "BMC MUSCULOSKEL DIS",
issn = "1471-2474",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Influence of leg axis alignment on MRI T2* mapping of the knee in young professional soccer players

AU - Dalos, D

AU - Marshall, P R

AU - Lissy, M

AU - Maas, K J

AU - Henes, F O

AU - Kaul, M G

AU - Kleinertz, H

AU - Frings, J

AU - Krause, M

AU - Frosch, K H

AU - Welsch, G H

N1 - © 2024. The Author(s).

PY - 2024/2/15

Y1 - 2024/2/15

N2 - BACKGROUND: Investigation of the association between leg axis alignment and biochemical MRI in young professional soccer players in order to identify a potential influence of the leg axis on cartilage regions at risk.METHODS: Sixteen professional soccer players (21 ± 3 years) underwent static and dynamic leg axis analysis via radiation free DIERS formetric 4 D as well as 3-T MRI examination of both knees. Quantitative T2* mapping of the knee cartilage was performed and T2* values were evaluated as 144 regions of interest. Subgroup analysis was performed in players with severe varus alignment (> 6°).RESULTS: Analysis of the leg axis geometry revealed a mean static alignment of 6.6° ± 2.5 varus and a mean dynamic alignment of 5.1° ± 2.6 varus. Quantitative T2* mapping showed significantly increased T2* values in the superficial cartilage layer compared to the deeper region (p < 0.001) as well as a significant increase in relaxation times in the femoral cartilage from anterior to intermediate to posterior (p < 0.001). Combination of both methods revealed a significant correlation for the degree of varus alignment and the femoral, posterior, deep region of the medial knee compartment (r = 0.4; p = 0.03). If severe varus alignment was present this region showed a significant increase in relaxation time compared to players with a less pronounced leg axis deviation (p = 0.003).CONCLUSION: This study demonstrates that varus alignment in young soccer players is associated with elevated T2* relaxation times in the deep cartilage layer of the medial, posterior, femoral compartment and might therefore be a contributing factor in the early pathogenesis of manifest cartilage lesions. Therefore, these findings should be considered in the development of preventive training programs.

AB - BACKGROUND: Investigation of the association between leg axis alignment and biochemical MRI in young professional soccer players in order to identify a potential influence of the leg axis on cartilage regions at risk.METHODS: Sixteen professional soccer players (21 ± 3 years) underwent static and dynamic leg axis analysis via radiation free DIERS formetric 4 D as well as 3-T MRI examination of both knees. Quantitative T2* mapping of the knee cartilage was performed and T2* values were evaluated as 144 regions of interest. Subgroup analysis was performed in players with severe varus alignment (> 6°).RESULTS: Analysis of the leg axis geometry revealed a mean static alignment of 6.6° ± 2.5 varus and a mean dynamic alignment of 5.1° ± 2.6 varus. Quantitative T2* mapping showed significantly increased T2* values in the superficial cartilage layer compared to the deeper region (p < 0.001) as well as a significant increase in relaxation times in the femoral cartilage from anterior to intermediate to posterior (p < 0.001). Combination of both methods revealed a significant correlation for the degree of varus alignment and the femoral, posterior, deep region of the medial knee compartment (r = 0.4; p = 0.03). If severe varus alignment was present this region showed a significant increase in relaxation time compared to players with a less pronounced leg axis deviation (p = 0.003).CONCLUSION: This study demonstrates that varus alignment in young soccer players is associated with elevated T2* relaxation times in the deep cartilage layer of the medial, posterior, femoral compartment and might therefore be a contributing factor in the early pathogenesis of manifest cartilage lesions. Therefore, these findings should be considered in the development of preventive training programs.

KW - Humans

KW - Soccer

KW - Leg

KW - Cartilage, Articular/diagnostic imaging

KW - Knee Joint/diagnostic imaging

KW - Magnetic Resonance Imaging/methods

U2 - 10.1186/s12891-024-07233-3

DO - 10.1186/s12891-024-07233-3

M3 - SCORING: Journal article

C2 - 38360606

VL - 25

SP - 144

JO - BMC MUSCULOSKEL DIS

JF - BMC MUSCULOSKEL DIS

SN - 1471-2474

IS - 1

ER -