Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation.

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Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation. / Fehse, Natalja; Fehse, Boris; Kröger, Nicolaus-Martin; Zabelina, Tatjana; Freiberger, Petra; Krüger, William; Kabisch, Hartmut; Erttmann, Rudolf; Zander, Axel.

in: J HEMATOTH STEM CELL, Jahrgang 12, Nr. 2, 2, 2003, S. 237-242.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{b5c08c4e0df84161a6b27055b47557a7,
title = "Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation.",
abstract = "The aim of this work was to analyze the influence of anti-thymocyte globulin (ATG) as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation. The rate and pattern of the recovery of total lymphocytes, natural killer (NK) cells, and several T and B cell subsets were determined in 38 patients for more than 2 years following BMT. We compared two patient groups: the first comprised 19 patients after matched related BMT without ATG prevention for graft-versus-host disease (GVHD) and the second contained 19 patients after matched related BMT with ATG treatment for GVHD prophylaxis. We observed impaired immune reconstitution in the ATG group in comparison with the non-ATG group, indicating a significant influence of ATG on immune recovery for several months after BMT.",
author = "Natalja Fehse and Boris Fehse and Nicolaus-Martin Kr{\"o}ger and Tatjana Zabelina and Petra Freiberger and William Kr{\"u}ger and Hartmut Kabisch and Rudolf Erttmann and Axel Zander",
year = "2003",
language = "Deutsch",
volume = "12",
pages = "237--242",
journal = "J HEMATOTH STEM CELL",
issn = "1525-8165",
publisher = "Mary Ann Liebert Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation.

AU - Fehse, Natalja

AU - Fehse, Boris

AU - Kröger, Nicolaus-Martin

AU - Zabelina, Tatjana

AU - Freiberger, Petra

AU - Krüger, William

AU - Kabisch, Hartmut

AU - Erttmann, Rudolf

AU - Zander, Axel

PY - 2003

Y1 - 2003

N2 - The aim of this work was to analyze the influence of anti-thymocyte globulin (ATG) as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation. The rate and pattern of the recovery of total lymphocytes, natural killer (NK) cells, and several T and B cell subsets were determined in 38 patients for more than 2 years following BMT. We compared two patient groups: the first comprised 19 patients after matched related BMT without ATG prevention for graft-versus-host disease (GVHD) and the second contained 19 patients after matched related BMT with ATG treatment for GVHD prophylaxis. We observed impaired immune reconstitution in the ATG group in comparison with the non-ATG group, indicating a significant influence of ATG on immune recovery for several months after BMT.

AB - The aim of this work was to analyze the influence of anti-thymocyte globulin (ATG) as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation. The rate and pattern of the recovery of total lymphocytes, natural killer (NK) cells, and several T and B cell subsets were determined in 38 patients for more than 2 years following BMT. We compared two patient groups: the first comprised 19 patients after matched related BMT without ATG prevention for graft-versus-host disease (GVHD) and the second contained 19 patients after matched related BMT with ATG treatment for GVHD prophylaxis. We observed impaired immune reconstitution in the ATG group in comparison with the non-ATG group, indicating a significant influence of ATG on immune recovery for several months after BMT.

M3 - SCORING: Zeitschriftenaufsatz

VL - 12

SP - 237

EP - 242

JO - J HEMATOTH STEM CELL

JF - J HEMATOTH STEM CELL

SN - 1525-8165

IS - 2

M1 - 2

ER -