PortalPublikationenIndividual patient data meta-analysis shows no association b...

Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity.

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  • Gillian C Barnett
  • Rebecca M Elliott
  • Jan Alsner
  • Christian N Andreassen
  • Osama Abdelhay
  • Neil G Burnet
  • Jenny Chang-Claude
  • Charlotte E Coles
  • Sara Gutiérrez-Enríquez
  • Maria J Fuentes-Raspall
  • Maria C Alonso-Muñoz
  • Sarah Kerns
  • Annette Raabe
  • R Paul Symonds
  • Petra Seibold
  • Chris J Talbot
  • Frederik Wenz
  • Jennifer Wilkinson
  • John Yarnold
  • Alison M Dunning
  • Barry S Rosenstein
  • Catharine M L West
  • Søren M Bentzen

Beteiligte Einrichtungen

Abstract

Reported associations between risk of radiation-induced normal tissue injury and single nucleotide polymorphisms (SNPs) in TGFB1, encoding the pro-fibrotic cytokine transforming growth factor-beta 1 (TGF-?1), remain controversial. To overcome publication bias, the international Radiogenomics Consortium collected and analysed individual patient level data from both published and unpublished studies.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer3
ISSN0167-8140
StatusVeröffentlicht - 2012
pubmed 23199655