Incomplete remission and treatment resistance in first-episode psychosis: definition, prevalence and predictors.
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Incomplete remission and treatment resistance in first-episode psychosis: definition, prevalence and predictors. / Huber, Christian; Naber, Dieter; Lambert, Martin.
in: EXPERT OPIN PHARMACO, Jahrgang 9, Nr. 12, 12, 2008, S. 2027-2038.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Incomplete remission and treatment resistance in first-episode psychosis: definition, prevalence and predictors.
AU - Huber, Christian
AU - Naber, Dieter
AU - Lambert, Martin
PY - 2008
Y1 - 2008
N2 - BACKGROUND: Up to 50% of first-episode psychosis patients suffer from long-term incomplete remission or treatment resistance. Different definitions for these terms have been used in psychiatric research, making generalized statements about the prevalence and predictors of treatment resistance difficult. OBJECTIVE: The aim of this study was to give an overview on state-of-the-art definitions of treatment resistance for each of the diagnoses making up the inhomogeneous diagnostic entity 'psychosis' and to analyze the factors leading to treatment resistance. METHODS: A computerized and manual literature search for relevant articles published within recent years was undertaken. RESULTS: In addition to symptomatic criteria, patients' functional level and quality of life have to be considered in the definition of treatment resistance. Patient-related, illness-related and treatment-related predictors of treatment resistance and incomplete remission might help to identify subjects at risk and optimize interventions.
AB - BACKGROUND: Up to 50% of first-episode psychosis patients suffer from long-term incomplete remission or treatment resistance. Different definitions for these terms have been used in psychiatric research, making generalized statements about the prevalence and predictors of treatment resistance difficult. OBJECTIVE: The aim of this study was to give an overview on state-of-the-art definitions of treatment resistance for each of the diagnoses making up the inhomogeneous diagnostic entity 'psychosis' and to analyze the factors leading to treatment resistance. METHODS: A computerized and manual literature search for relevant articles published within recent years was undertaken. RESULTS: In addition to symptomatic criteria, patients' functional level and quality of life have to be considered in the definition of treatment resistance. Patient-related, illness-related and treatment-related predictors of treatment resistance and incomplete remission might help to identify subjects at risk and optimize interventions.
M3 - SCORING: Zeitschriftenaufsatz
VL - 9
SP - 2027
EP - 2038
JO - EXPERT OPIN PHARMACO
JF - EXPERT OPIN PHARMACO
SN - 1465-6566
IS - 12
M1 - 12
ER -
