Implications of thermogenic adipose tissues for metabolic health

Christian Schlein; Joerg Heeren

doi:10.1016/j.beem.2016.08.002

Implications of thermogenic adipose tissues for metabolic health

Standard

Implications of thermogenic adipose tissues for metabolic health. / Schlein, Christian ; Heeren, Joerg.

in: BEST PRACT RES CL EN, Jahrgang 30, Nr. 4, 08.2016, S. 487-496.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schlein, C & Heeren, J 2016, 'Implications of thermogenic adipose tissues for metabolic health', BEST PRACT RES CL EN, Jg. 30, Nr. 4, S. 487-496. https://doi.org/10.1016/j.beem.2016.08.002

APA

Schlein, C., & Heeren, J. (2016). Implications of thermogenic adipose tissues for metabolic health. BEST PRACT RES CL EN, 30(4), 487-496. https://doi.org/10.1016/j.beem.2016.08.002

Vancouver

Schlein C , Heeren J. Implications of thermogenic adipose tissues for metabolic health. BEST PRACT RES CL EN. 2016 Aug;30(4):487-496. https://doi.org/10.1016/j.beem.2016.08.002

Bibtex

@article{42e274ef5d00448a93059aeb290613a5,

title = "Implications of thermogenic adipose tissues for metabolic health",

abstract = "Excess and ectopic fat accumulation in obesity is a major risk factor for developing hyperlipidemia, type 2 diabetes and cardiovascular disease. The activation of brown and/or beige adipocytes is a promising target for the treatment of metabolic disorders as the combustion of excess energy by these thermogenic adipocytes may help losing weight and improving plasma parameters including triglyceride, cholesterol and glucose levels. The regulation of heat production by thermogenic adipose tissues is based on a complex crosstalk between the autonomous nervous system, intracellular and secreted factors. This multifaceted alignment regulates thermogenic demands to environmental circumstances in dependence on available energy resources. This review summarizes the current knowledge how thermogenic tissues can be targeted to combat the burden of diseases with a special focus on lipid metabolism and diseases related to lipoprotein metabolism.",

author = "Christian Schlein and Joerg Heeren",

year = "2016",

month = aug,

doi = "10.1016/j.beem.2016.08.002",

language = "English",

volume = "30",

pages = "487--496",

journal = "BEST PRACT RES CL EN",

issn = "1521-690X",

publisher = "ELSEVIER SCI LTD",

number = "4",

}

RIS

TY - JOUR

T1 - Implications of thermogenic adipose tissues for metabolic health

AU - Schlein, Christian

AU - Heeren, Joerg

PY - 2016/8

Y1 - 2016/8

N2 - Excess and ectopic fat accumulation in obesity is a major risk factor for developing hyperlipidemia, type 2 diabetes and cardiovascular disease. The activation of brown and/or beige adipocytes is a promising target for the treatment of metabolic disorders as the combustion of excess energy by these thermogenic adipocytes may help losing weight and improving plasma parameters including triglyceride, cholesterol and glucose levels. The regulation of heat production by thermogenic adipose tissues is based on a complex crosstalk between the autonomous nervous system, intracellular and secreted factors. This multifaceted alignment regulates thermogenic demands to environmental circumstances in dependence on available energy resources. This review summarizes the current knowledge how thermogenic tissues can be targeted to combat the burden of diseases with a special focus on lipid metabolism and diseases related to lipoprotein metabolism.

AB - Excess and ectopic fat accumulation in obesity is a major risk factor for developing hyperlipidemia, type 2 diabetes and cardiovascular disease. The activation of brown and/or beige adipocytes is a promising target for the treatment of metabolic disorders as the combustion of excess energy by these thermogenic adipocytes may help losing weight and improving plasma parameters including triglyceride, cholesterol and glucose levels. The regulation of heat production by thermogenic adipose tissues is based on a complex crosstalk between the autonomous nervous system, intracellular and secreted factors. This multifaceted alignment regulates thermogenic demands to environmental circumstances in dependence on available energy resources. This review summarizes the current knowledge how thermogenic tissues can be targeted to combat the burden of diseases with a special focus on lipid metabolism and diseases related to lipoprotein metabolism.

U2 - 10.1016/j.beem.2016.08.002

DO - 10.1016/j.beem.2016.08.002

M3 - SCORING: Journal article

C2 - 27697210

VL - 30

SP - 487

EP - 496

JO - BEST PRACT RES CL EN

JF - BEST PRACT RES CL EN

SN - 1521-690X

IS - 4

ER -