Impact of the position of a gap on the response of the R1H-tumor of the rat on fractionated split-course radiotherapy.
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Impact of the position of a gap on the response of the R1H-tumor of the rat on fractionated split-course radiotherapy. / Zieron, J O; Omniczynski, M; Raabe, A; Beck-Bornholdt, Hans-Peter.
in: STRAHLENTHER ONKOL, Jahrgang 177, Nr. 11, 11, 2001, S. 592-596.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Impact of the position of a gap on the response of the R1H-tumor of the rat on fractionated split-course radiotherapy.
AU - Zieron, J O
AU - Omniczynski, M
AU - Raabe, A
AU - Beck-Bornholdt, Hans-Peter
PY - 2001
Y1 - 2001
N2 - BACKGROUND: Gaps are a common feature of clinical radiotherapy. Only little information is available about the influence of the position of a gap on tumor response. MATERIAL AND METHODS: In a rodent tumor model (rhabdomyosarcoma R1H of the rat) three split-course schedules were carried out by inserting a 2-week gap either after the 1st, the 3rd, or the 5th week into a standard schedule of 30 fractions in 6 weeks. For comparison a standard and an accelerated treatment were carried out. RESULT AND CONCLUSION: The position of the gap was found to have a significant influence on the tumor response (p = 0.018).
AB - BACKGROUND: Gaps are a common feature of clinical radiotherapy. Only little information is available about the influence of the position of a gap on tumor response. MATERIAL AND METHODS: In a rodent tumor model (rhabdomyosarcoma R1H of the rat) three split-course schedules were carried out by inserting a 2-week gap either after the 1st, the 3rd, or the 5th week into a standard schedule of 30 fractions in 6 weeks. For comparison a standard and an accelerated treatment were carried out. RESULT AND CONCLUSION: The position of the gap was found to have a significant influence on the tumor response (p = 0.018).
M3 - SCORING: Zeitschriftenaufsatz
VL - 177
SP - 592
EP - 596
JO - STRAHLENTHER ONKOL
JF - STRAHLENTHER ONKOL
SN - 0179-7158
IS - 11
M1 - 11
ER -