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Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry

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Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry. / Hoffmann, Boris A; Kuck, Karl-Heinz; Andresen, Dietrich; Spitzer, Stefan G; Hoffmann, Ellen; Schumacher, Burghard; Eckardt, Lars; Brachmann, Johannes; Becker, Rüdiger; Steven, Daniel; Rostock, Thomas; Jünger, Claus; Senges, Jochen; Willems, Stephan.

in: J CARDIOVASC ELECTR, Jahrgang 25, Nr. 3, 03.2014, S. 242-249.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hoffmann, BA, Kuck, K-H, Andresen, D, Spitzer, SG, Hoffmann, E, Schumacher, B, Eckardt, L, Brachmann, J, Becker, R, Steven, D, Rostock, T, Jünger, C, Senges, J & Willems, S 2014, 'Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry', J CARDIOVASC ELECTR, Jg. 25, Nr. 3, S. 242-249. https://doi.org/10.1111/jce.12319

APA

Hoffmann, B. A., Kuck, K-H., Andresen, D., Spitzer, S. G., Hoffmann, E., Schumacher, B., Eckardt, L., Brachmann, J., Becker, R., Steven, D., Rostock, T., Jünger, C., Senges, J., & Willems, S. (2014). Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry. J CARDIOVASC ELECTR, 25(3), 242-249. https://doi.org/10.1111/jce.12319

Vancouver

Hoffmann BA, Kuck K-H, Andresen D, Spitzer SG, Hoffmann E, Schumacher B et al. Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry. J CARDIOVASC ELECTR. 2014 Mär;25(3):242-249. https://doi.org/10.1111/jce.12319

Bibtex

@article{f5cf7c44d297455ba1ff515b62ef0a46,
title = "Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry",
abstract = "INTRODUCTION: Catheter ablation (CA) has emerged as a widespread therapeutic option in the treatment of atrial fibrillation (AF). Currently, no safety data with regard to the impact of the underlying structural heart diseases (SHD) are available. We sought to assess the risk for acute and long-term complications during CA of AF in relation to underlying SHD.METHODS AND RESULTS: We included 6,211 patients in a prospective registry undergoing CA of AF in 41 nationwide centers. All patients were divided into 4 groups according to the underlying heart disease: No SHD (69.4%), hypertensive heart disease (HHD) (12.0%), coronary artery disease (CAD) (15.1%), and cardiomyopathy (CM) (3.6%). In univariate analysis, patients with HHD had an overall complication rate of 7.28%, whereas patients without an SHD had a significantly lower rate of 6.01% (P < 0.01). Multivariate analysis revealed that HHD (adjusted odds ratio [OR]: 1.97 [95% confidence interval (CI): 1.02-3.83], P = 0.0442) and age (years; OR: 1.04 [95% CI: 1.01-1.07], P = 0.0155) were independent predictors of severe, nonfatal complications and death. Other SHD including CAD (OR: 1.48 (0.73-3.00), P = 0.2797) and CM (OR: 2.37 [0.70-7.99], P = 0.1630) failed to reach statistical significance. Male sex was protective (OR: 0.47 [95% CI: 0.27-0.81], P = 0.0062).CONCLUSION: In general, CA of AF has a low number of severe complications. In our prospective registry HHD emerged as an independent predictor of severe, nonfatal complications during AF ablation but other SHD including CAD and CM did not. The influence of HHD on the complication rate should be considered in patient selection.",
keywords = "Aged, Atrial Fibrillation/diagnosis, Catheter Ablation/adverse effects, Female, Follow-Up Studies, Germany/epidemiology, Heart Diseases/epidemiology, Humans, Male, Middle Aged, Postoperative Complications/diagnosis, Prospective Studies, Registries, Treatment Outcome",
author = "Hoffmann, {Boris A} and Karl-Heinz Kuck and Dietrich Andresen and Spitzer, {Stefan G} and Ellen Hoffmann and Burghard Schumacher and Lars Eckardt and Johannes Brachmann and R{\"u}diger Becker and Daniel Steven and Thomas Rostock and Claus J{\"u}nger and Jochen Senges and Stephan Willems",
note = "{\textcopyright} 2013 Wiley Periodicals, Inc.",
year = "2014",
month = mar,
doi = "10.1111/jce.12319",
language = "English",
volume = "25",
pages = "242--249",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Impact of structural heart disease on the acute complication rate in atrial fibrillation ablation: results from the German Ablation Registry

AU - Hoffmann, Boris A

AU - Kuck, Karl-Heinz

AU - Andresen, Dietrich

AU - Spitzer, Stefan G

AU - Hoffmann, Ellen

AU - Schumacher, Burghard

AU - Eckardt, Lars

AU - Brachmann, Johannes

AU - Becker, Rüdiger

AU - Steven, Daniel

AU - Rostock, Thomas

AU - Jünger, Claus

AU - Senges, Jochen

AU - Willems, Stephan

N1 - © 2013 Wiley Periodicals, Inc.

PY - 2014/3

Y1 - 2014/3

N2 - INTRODUCTION: Catheter ablation (CA) has emerged as a widespread therapeutic option in the treatment of atrial fibrillation (AF). Currently, no safety data with regard to the impact of the underlying structural heart diseases (SHD) are available. We sought to assess the risk for acute and long-term complications during CA of AF in relation to underlying SHD.METHODS AND RESULTS: We included 6,211 patients in a prospective registry undergoing CA of AF in 41 nationwide centers. All patients were divided into 4 groups according to the underlying heart disease: No SHD (69.4%), hypertensive heart disease (HHD) (12.0%), coronary artery disease (CAD) (15.1%), and cardiomyopathy (CM) (3.6%). In univariate analysis, patients with HHD had an overall complication rate of 7.28%, whereas patients without an SHD had a significantly lower rate of 6.01% (P < 0.01). Multivariate analysis revealed that HHD (adjusted odds ratio [OR]: 1.97 [95% confidence interval (CI): 1.02-3.83], P = 0.0442) and age (years; OR: 1.04 [95% CI: 1.01-1.07], P = 0.0155) were independent predictors of severe, nonfatal complications and death. Other SHD including CAD (OR: 1.48 (0.73-3.00), P = 0.2797) and CM (OR: 2.37 [0.70-7.99], P = 0.1630) failed to reach statistical significance. Male sex was protective (OR: 0.47 [95% CI: 0.27-0.81], P = 0.0062).CONCLUSION: In general, CA of AF has a low number of severe complications. In our prospective registry HHD emerged as an independent predictor of severe, nonfatal complications during AF ablation but other SHD including CAD and CM did not. The influence of HHD on the complication rate should be considered in patient selection.

AB - INTRODUCTION: Catheter ablation (CA) has emerged as a widespread therapeutic option in the treatment of atrial fibrillation (AF). Currently, no safety data with regard to the impact of the underlying structural heart diseases (SHD) are available. We sought to assess the risk for acute and long-term complications during CA of AF in relation to underlying SHD.METHODS AND RESULTS: We included 6,211 patients in a prospective registry undergoing CA of AF in 41 nationwide centers. All patients were divided into 4 groups according to the underlying heart disease: No SHD (69.4%), hypertensive heart disease (HHD) (12.0%), coronary artery disease (CAD) (15.1%), and cardiomyopathy (CM) (3.6%). In univariate analysis, patients with HHD had an overall complication rate of 7.28%, whereas patients without an SHD had a significantly lower rate of 6.01% (P < 0.01). Multivariate analysis revealed that HHD (adjusted odds ratio [OR]: 1.97 [95% confidence interval (CI): 1.02-3.83], P = 0.0442) and age (years; OR: 1.04 [95% CI: 1.01-1.07], P = 0.0155) were independent predictors of severe, nonfatal complications and death. Other SHD including CAD (OR: 1.48 (0.73-3.00), P = 0.2797) and CM (OR: 2.37 [0.70-7.99], P = 0.1630) failed to reach statistical significance. Male sex was protective (OR: 0.47 [95% CI: 0.27-0.81], P = 0.0062).CONCLUSION: In general, CA of AF has a low number of severe complications. In our prospective registry HHD emerged as an independent predictor of severe, nonfatal complications during AF ablation but other SHD including CAD and CM did not. The influence of HHD on the complication rate should be considered in patient selection.

KW - Aged

KW - Atrial Fibrillation/diagnosis

KW - Catheter Ablation/adverse effects

KW - Female

KW - Follow-Up Studies

KW - Germany/epidemiology

KW - Heart Diseases/epidemiology

KW - Humans

KW - Male

KW - Middle Aged

KW - Postoperative Complications/diagnosis

KW - Prospective Studies

KW - Registries

KW - Treatment Outcome

U2 - 10.1111/jce.12319

DO - 10.1111/jce.12319

M3 - SCORING: Journal article

C2 - 24237758

VL - 25

SP - 242

EP - 249

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 3

ER -