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Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011

Standard

Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011. / May, Matthias; Fritsche, Hans-Martin; Vetterlein, Malte W; Bastian, Patrick J; Gierth, Michael; Nuhn, Philipp; Aziz, Atiqullah; Fisch, Margit; Stief, Christian G; Hohenfellner, Markus; Wirth, Manfred P; Novotny, Vladimir; Hakenberg, Oliver W; Noldus, Joachim; Gilfrich, Christian; Bolenz, Christian; Burger, Maximilian; Brookman-May, Sabine D; PROMETRICS 2011 study group.

in: WORLD J UROL, Jahrgang 35, Nr. 2, 02.2017, S. 245-250.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

May, M, Fritsche, H-M, Vetterlein, MW, Bastian, PJ, Gierth, M, Nuhn, P, Aziz, A, Fisch, M, Stief, CG, Hohenfellner, M, Wirth, MP, Novotny, V, Hakenberg, OW, Noldus, J, Gilfrich, C, Bolenz, C, Burger, M, Brookman-May, SD & PROMETRICS 2011 study group 2017, 'Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011', WORLD J UROL, Jg. 35, Nr. 2, S. 245-250. https://doi.org/10.1007/s00345-016-1877-4

APA

May, M., Fritsche, H-M., Vetterlein, M. W., Bastian, P. J., Gierth, M., Nuhn, P., Aziz, A., Fisch, M., Stief, C. G., Hohenfellner, M., Wirth, M. P., Novotny, V., Hakenberg, O. W., Noldus, J., Gilfrich, C., Bolenz, C., Burger, M., Brookman-May, S. D., & PROMETRICS 2011 study group (2017). Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011. WORLD J UROL, 35(2), 245-250. https://doi.org/10.1007/s00345-016-1877-4

Vancouver

May M, Fritsche H-M, Vetterlein MW, Bastian PJ, Gierth M, Nuhn P et al. Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011. WORLD J UROL. 2017 Feb;35(2):245-250. https://doi.org/10.1007/s00345-016-1877-4

Bibtex

@article{484ba94bc9e14a8d9f1bfb4b435ead63,
title = "Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011",
abstract = "PURPOSE: Results of a retrospective single-institution study recently suggested improved prognostic outcomes in patients undergoing photodynamic diagnosis (PDD)-assisted transurethral resection of bladder tumor (TURBT) prior to radical cystectomy (RC). We sought to validate the prognostic influence of PDD-assisted TURBT on survival after RC by relying on a multi-institutional dataset.METHODS: To provide a homogeneous study population, patients with organ metastasis at the time of RC and/or after neoadjuvant chemotherapy were excluded from analysis, which resulted in overall 549 bladder cancer (BC) patients from 18 centers of the Prospective Multicenter Radical Cystectomy Series 2011 (PROMETRICS 2011). To evaluate the influence of PDD conducted during primary or final TURBT on cancer-specific mortality (CSM) and overall mortality (OM) after RC, bootstrap-corrected multivariate Cox proportional-hazards regression models were applied (median follow-up: 25 months; IQR: 19-30). Sensitivity analyses were performed for both patients with pure urothelial carcinoma and patients undergoing one single TURBT only.RESULTS: In 88 (16.0 %) and 100 (18.2 %) patients, PDD was used in primary and final TURBTs, respectively. In 335 (61.0 %) patients, a single TURBT was performed prior to RC; in 194 patients (35.3 %), TURBT had been performed in a different center. CSM and OM rates at 3 years were 32 and 40 %, respectively. Use of PDD during primary or final TURBT was no independent predictor of CSM or OM. These results were internally valid and were confirmed in sensitivity analyses.CONCLUSIONS: PDD utilization during TURBT prior to RC does not independently impact the prognosis of BC patients after RC.",
author = "Matthias May and Hans-Martin Fritsche and Vetterlein, {Malte W} and Bastian, {Patrick J} and Michael Gierth and Philipp Nuhn and Atiqullah Aziz and Margit Fisch and Stief, {Christian G} and Markus Hohenfellner and Wirth, {Manfred P} and Vladimir Novotny and Hakenberg, {Oliver W} and Joachim Noldus and Christian Gilfrich and Christian Bolenz and Maximilian Burger and Brookman-May, {Sabine D} and {PROMETRICS 2011 study group}",
year = "2017",
month = feb,
doi = "10.1007/s00345-016-1877-4",
language = "English",
volume = "35",
pages = "245--250",
journal = "WORLD J UROL",
issn = "0724-4983",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Impact of photodynamic diagnosis-assisted transurethral resection of bladder tumors on the prognostic outcome after radical cystectomy: Results from PROMETRICS 2011

AU - May, Matthias

AU - Fritsche, Hans-Martin

AU - Vetterlein, Malte W

AU - Bastian, Patrick J

AU - Gierth, Michael

AU - Nuhn, Philipp

AU - Aziz, Atiqullah

AU - Fisch, Margit

AU - Stief, Christian G

AU - Hohenfellner, Markus

AU - Wirth, Manfred P

AU - Novotny, Vladimir

AU - Hakenberg, Oliver W

AU - Noldus, Joachim

AU - Gilfrich, Christian

AU - Bolenz, Christian

AU - Burger, Maximilian

AU - Brookman-May, Sabine D

AU - PROMETRICS 2011 study group

PY - 2017/2

Y1 - 2017/2

N2 - PURPOSE: Results of a retrospective single-institution study recently suggested improved prognostic outcomes in patients undergoing photodynamic diagnosis (PDD)-assisted transurethral resection of bladder tumor (TURBT) prior to radical cystectomy (RC). We sought to validate the prognostic influence of PDD-assisted TURBT on survival after RC by relying on a multi-institutional dataset.METHODS: To provide a homogeneous study population, patients with organ metastasis at the time of RC and/or after neoadjuvant chemotherapy were excluded from analysis, which resulted in overall 549 bladder cancer (BC) patients from 18 centers of the Prospective Multicenter Radical Cystectomy Series 2011 (PROMETRICS 2011). To evaluate the influence of PDD conducted during primary or final TURBT on cancer-specific mortality (CSM) and overall mortality (OM) after RC, bootstrap-corrected multivariate Cox proportional-hazards regression models were applied (median follow-up: 25 months; IQR: 19-30). Sensitivity analyses were performed for both patients with pure urothelial carcinoma and patients undergoing one single TURBT only.RESULTS: In 88 (16.0 %) and 100 (18.2 %) patients, PDD was used in primary and final TURBTs, respectively. In 335 (61.0 %) patients, a single TURBT was performed prior to RC; in 194 patients (35.3 %), TURBT had been performed in a different center. CSM and OM rates at 3 years were 32 and 40 %, respectively. Use of PDD during primary or final TURBT was no independent predictor of CSM or OM. These results were internally valid and were confirmed in sensitivity analyses.CONCLUSIONS: PDD utilization during TURBT prior to RC does not independently impact the prognosis of BC patients after RC.

AB - PURPOSE: Results of a retrospective single-institution study recently suggested improved prognostic outcomes in patients undergoing photodynamic diagnosis (PDD)-assisted transurethral resection of bladder tumor (TURBT) prior to radical cystectomy (RC). We sought to validate the prognostic influence of PDD-assisted TURBT on survival after RC by relying on a multi-institutional dataset.METHODS: To provide a homogeneous study population, patients with organ metastasis at the time of RC and/or after neoadjuvant chemotherapy were excluded from analysis, which resulted in overall 549 bladder cancer (BC) patients from 18 centers of the Prospective Multicenter Radical Cystectomy Series 2011 (PROMETRICS 2011). To evaluate the influence of PDD conducted during primary or final TURBT on cancer-specific mortality (CSM) and overall mortality (OM) after RC, bootstrap-corrected multivariate Cox proportional-hazards regression models were applied (median follow-up: 25 months; IQR: 19-30). Sensitivity analyses were performed for both patients with pure urothelial carcinoma and patients undergoing one single TURBT only.RESULTS: In 88 (16.0 %) and 100 (18.2 %) patients, PDD was used in primary and final TURBTs, respectively. In 335 (61.0 %) patients, a single TURBT was performed prior to RC; in 194 patients (35.3 %), TURBT had been performed in a different center. CSM and OM rates at 3 years were 32 and 40 %, respectively. Use of PDD during primary or final TURBT was no independent predictor of CSM or OM. These results were internally valid and were confirmed in sensitivity analyses.CONCLUSIONS: PDD utilization during TURBT prior to RC does not independently impact the prognosis of BC patients after RC.

U2 - 10.1007/s00345-016-1877-4

DO - 10.1007/s00345-016-1877-4

M3 - SCORING: Journal article

C2 - 27300339

VL - 35

SP - 245

EP - 250

JO - WORLD J UROL

JF - WORLD J UROL

SN - 0724-4983

IS - 2

ER -