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Immune-mediated entities of (primary) focal segmental glomerulosclerosis

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Immune-mediated entities of (primary) focal segmental glomerulosclerosis. / Braun, Fabian; Homeyer, Inka; Alachkar, Nada; Huber, Tobias B.

in: CELL TISSUE RES, Jahrgang 385, Nr. 2, 08.2021, S. 423-434.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Braun, F, Homeyer, I, Alachkar, N & Huber, TB 2021, 'Immune-mediated entities of (primary) focal segmental glomerulosclerosis', CELL TISSUE RES, Jg. 385, Nr. 2, S. 423-434. https://doi.org/10.1007/s00441-021-03454-3

APA

Braun, F., Homeyer, I., Alachkar, N., & Huber, T. B. (2021). Immune-mediated entities of (primary) focal segmental glomerulosclerosis. CELL TISSUE RES, 385(2), 423-434. https://doi.org/10.1007/s00441-021-03454-3

Vancouver

Braun F, Homeyer I, Alachkar N, Huber TB. Immune-mediated entities of (primary) focal segmental glomerulosclerosis. CELL TISSUE RES. 2021 Aug;385(2):423-434. https://doi.org/10.1007/s00441-021-03454-3

Bibtex

@article{6fee619c9d8743a0be3da38b36a0316a,
title = "Immune-mediated entities of (primary) focal segmental glomerulosclerosis",
abstract = "Focal segmental glomerulosclerosis (FSGS) represents a glomerular scar formation downstream of various different mechanisms leading to podocytopathy and podocyte loss. Recently, significant advances were made in understanding genetic factors, podocyte intrinsic mechanisms, and adaptive mechanisms causing FSGS. However, while most cases of nephrotic FSGS are being treated with immunosuppressants, the underlying immune dysregulation, involved immune cells, and soluble factors are only incompletely understood. Thus, we here summarize the current knowledge of proposed immune effector cells, secreted soluble factors, and podocyte response in immune-mediated (primary) FSGS.",
author = "Fabian Braun and Inka Homeyer and Nada Alachkar and Huber, {Tobias B}",
year = "2021",
month = aug,
doi = "10.1007/s00441-021-03454-3",
language = "English",
volume = "385",
pages = "423--434",
journal = "CELL TISSUE RES",
issn = "0302-766X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Immune-mediated entities of (primary) focal segmental glomerulosclerosis

AU - Braun, Fabian

AU - Homeyer, Inka

AU - Alachkar, Nada

AU - Huber, Tobias B

PY - 2021/8

Y1 - 2021/8

N2 - Focal segmental glomerulosclerosis (FSGS) represents a glomerular scar formation downstream of various different mechanisms leading to podocytopathy and podocyte loss. Recently, significant advances were made in understanding genetic factors, podocyte intrinsic mechanisms, and adaptive mechanisms causing FSGS. However, while most cases of nephrotic FSGS are being treated with immunosuppressants, the underlying immune dysregulation, involved immune cells, and soluble factors are only incompletely understood. Thus, we here summarize the current knowledge of proposed immune effector cells, secreted soluble factors, and podocyte response in immune-mediated (primary) FSGS.

AB - Focal segmental glomerulosclerosis (FSGS) represents a glomerular scar formation downstream of various different mechanisms leading to podocytopathy and podocyte loss. Recently, significant advances were made in understanding genetic factors, podocyte intrinsic mechanisms, and adaptive mechanisms causing FSGS. However, while most cases of nephrotic FSGS are being treated with immunosuppressants, the underlying immune dysregulation, involved immune cells, and soluble factors are only incompletely understood. Thus, we here summarize the current knowledge of proposed immune effector cells, secreted soluble factors, and podocyte response in immune-mediated (primary) FSGS.

U2 - 10.1007/s00441-021-03454-3

DO - 10.1007/s00441-021-03454-3

M3 - SCORING: Review article

C2 - 33907872

VL - 385

SP - 423

EP - 434

JO - CELL TISSUE RES

JF - CELL TISSUE RES

SN - 0302-766X

IS - 2

ER -