Identical lesion morphology in primary progressive and relapsing-remitting MS--an ultrahigh field MRI study
Abstract
Potential differences between primary progressive (PP) and relapsing-remitting (RR) multiple sclerosis (MS) have been controversially discussed. In this study, we compared lesion morphology and distribution in patients with PPMS and RRMS (nine in each group) using 7 T MRI. We found that gray and white matter lesions in PPMS and RRMS patients did not differ in their respective morphological characteristics (e.g., perivascular p = 0.863, hypointense rim p = 0.796, cortical lesion count p = 0.436). Although limited by a small sample size, our study results suggest that PPMS and RRMS, despite differences in disease course and clinical characteristics, exhibit identical lesion morphology under ultrahigh field MRI.
Bibliografische Daten
Originalsprache | Englisch |
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ISSN | 1352-4585 |
DOIs | |
Status | Veröffentlicht - 12.2014 |
Extern publiziert | Ja |
Anmerkungen des Dekanats
© The Author(s), 2014.
PubMed | 24781284 |
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