Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.

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Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression. / Lange, Tobias; Ullrich, Sebastian; Müller, Imke; Nentwich, Michael; Stübke, Katrin; Feldhaus, Susanne; Knies, Christine; Hellwinkel, Olaf; Vessella, Robert L; Abramjuk, Claudia; Anders, Mario; Schröder-Schwarz, Jennifer; Schlomm, Thorsten; Huland, Hartwig; Sauter, Guido; Schumacher, Udo.

in: CLIN CANCER RES, Jahrgang 18, Nr. 5, 5, 2012, S. 1364-1373.

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@article{6f635f3ad53e478b86b76692634ff5f2,
title = "Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.",
abstract = "To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients.",
keywords = "Adult, Animals, Humans, Male, Aged, Middle Aged, Adolescent, Young Adult, Child, Disease Progression, Disease Models, Animal, Mice, Mice, Inbred BALB C, Mice, Knockout, Cell Line, Tumor, Neoplasm Staging, Neoplasm Metastasis, Protein Binding, Nerve Tissue Proteins/metabolism, Transplantation, Heterologous, Tumor Markers, Biological/*metabolism, Prostatic Neoplasms/*metabolism/pathology, Lectins/metabolism, N-Acetylglucosaminyltransferases/metabolism, Oligosaccharides, Branched-Chain/*metabolism, Phytohemagglutinins/metabolism, Adult, Animals, Humans, Male, Aged, Middle Aged, Adolescent, Young Adult, Child, Disease Progression, Disease Models, Animal, Mice, Mice, Inbred BALB C, Mice, Knockout, Cell Line, Tumor, Neoplasm Staging, Neoplasm Metastasis, Protein Binding, Nerve Tissue Proteins/metabolism, Transplantation, Heterologous, Tumor Markers, Biological/*metabolism, Prostatic Neoplasms/*metabolism/pathology, Lectins/metabolism, N-Acetylglucosaminyltransferases/metabolism, Oligosaccharides, Branched-Chain/*metabolism, Phytohemagglutinins/metabolism",
author = "Tobias Lange and Sebastian Ullrich and Imke M{\"u}ller and Michael Nentwich and Katrin St{\"u}bke and Susanne Feldhaus and Christine Knies and Olaf Hellwinkel and Vessella, {Robert L} and Claudia Abramjuk and Mario Anders and Jennifer Schr{\"o}der-Schwarz and Thorsten Schlomm and Hartwig Huland and Guido Sauter and Udo Schumacher",
year = "2012",
language = "English",
volume = "18",
pages = "1364--1373",
journal = "CLIN CANCER RES",
issn = "1078-0432",
publisher = "American Association for Cancer Research Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.

AU - Lange, Tobias

AU - Ullrich, Sebastian

AU - Müller, Imke

AU - Nentwich, Michael

AU - Stübke, Katrin

AU - Feldhaus, Susanne

AU - Knies, Christine

AU - Hellwinkel, Olaf

AU - Vessella, Robert L

AU - Abramjuk, Claudia

AU - Anders, Mario

AU - Schröder-Schwarz, Jennifer

AU - Schlomm, Thorsten

AU - Huland, Hartwig

AU - Sauter, Guido

AU - Schumacher, Udo

PY - 2012

Y1 - 2012

N2 - To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients.

AB - To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients.

KW - Adult

KW - Animals

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Child

KW - Disease Progression

KW - Disease Models, Animal

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Knockout

KW - Cell Line, Tumor

KW - Neoplasm Staging

KW - Neoplasm Metastasis

KW - Protein Binding

KW - Nerve Tissue Proteins/metabolism

KW - Transplantation, Heterologous

KW - Tumor Markers, Biological/metabolism

KW - Prostatic Neoplasms/metabolism/pathology

KW - Lectins/metabolism

KW - N-Acetylglucosaminyltransferases/metabolism

KW - Oligosaccharides, Branched-Chain/metabolism

KW - Phytohemagglutinins/metabolism

KW - Adult

KW - Animals

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Child

KW - Disease Progression

KW - Disease Models, Animal

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Knockout

KW - Cell Line, Tumor

KW - Neoplasm Staging

KW - Neoplasm Metastasis

KW - Protein Binding

KW - Nerve Tissue Proteins/metabolism

KW - Transplantation, Heterologous

KW - Tumor Markers, Biological/metabolism

KW - Prostatic Neoplasms/metabolism/pathology

KW - Lectins/metabolism

KW - N-Acetylglucosaminyltransferases/metabolism

KW - Oligosaccharides, Branched-Chain/metabolism

KW - Phytohemagglutinins/metabolism

M3 - SCORING: Journal article

VL - 18

SP - 1364

EP - 1373

JO - CLIN CANCER RES

JF - CLIN CANCER RES

SN - 1078-0432

IS - 5

M1 - 5

ER -