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HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice

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HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice. / Valentiner, Ursula; Hall, Debbie M S; Brooks, Susan A; Schumacher, Udo.

in: CANCER LETT, Jahrgang 219, Nr. 2, 10.03.2005, S. 233-42.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Valentiner, U, Hall, DMS, Brooks, SA & Schumacher, U 2005, 'HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice', CANCER LETT, Jg. 219, Nr. 2, S. 233-42. https://doi.org/10.1016/j.canlet.2004.07.046

APA

Valentiner, U., Hall, D. M. S., Brooks, S. A., & Schumacher, U. (2005). HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice. CANCER LETT, 219(2), 233-42. https://doi.org/10.1016/j.canlet.2004.07.046

Vancouver

Valentiner U, Hall DMS, Brooks SA, Schumacher U. HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice. CANCER LETT. 2005 Mär 10;219(2):233-42. https://doi.org/10.1016/j.canlet.2004.07.046

Bibtex

@article{377eb9eb1e9f4d3aaaf825d52ac798f0,
title = "HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice",
abstract = "Six human breast cancer cell lines were injected subcutaneously into scid mice and their in vivo growth behaviour and HPA binding pattern were analysed. Furthermore, the role of HPA binding glycoconjugates concerning the adhesion to endothelial cells in vitro was investigated. Four of the tested cell lines engrafted in the scid mouse model but they showed considerable variations concerning their growth behaviour, their metastatic potential and their HPA binding pattern. HPA inhibited adhesive interactions between cell lines derived from metatstatic sources and tumour necrosis factor (TNF)alpha stimulated endothelial cells. The transplantation of HPA defined breast cancer cell lines into scid mice is a useful animal model for the research of breast cancer and its metastasis. The HPA binding glycoconjugates appear to be associated with adhesive interactions between metastasising tumour cells and endothelial cells.",
keywords = "Acetylgalactosamine, Animals, Breast, Cell Adhesion, Endothelium, Epithelial Cells, Female, Humans, Lectins, Mice, Mice, SCID, Neoplasm Metastasis, Neoplasm Transplantation, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha",
author = "Ursula Valentiner and Hall, {Debbie M S} and Brooks, {Susan A} and Udo Schumacher",
year = "2005",
month = mar,
day = "10",
doi = "10.1016/j.canlet.2004.07.046",
language = "English",
volume = "219",
pages = "233--42",
journal = "CANCER LETT",
issn = "0304-3835",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice

AU - Valentiner, Ursula

AU - Hall, Debbie M S

AU - Brooks, Susan A

AU - Schumacher, Udo

PY - 2005/3/10

Y1 - 2005/3/10

N2 - Six human breast cancer cell lines were injected subcutaneously into scid mice and their in vivo growth behaviour and HPA binding pattern were analysed. Furthermore, the role of HPA binding glycoconjugates concerning the adhesion to endothelial cells in vitro was investigated. Four of the tested cell lines engrafted in the scid mouse model but they showed considerable variations concerning their growth behaviour, their metastatic potential and their HPA binding pattern. HPA inhibited adhesive interactions between cell lines derived from metatstatic sources and tumour necrosis factor (TNF)alpha stimulated endothelial cells. The transplantation of HPA defined breast cancer cell lines into scid mice is a useful animal model for the research of breast cancer and its metastasis. The HPA binding glycoconjugates appear to be associated with adhesive interactions between metastasising tumour cells and endothelial cells.

AB - Six human breast cancer cell lines were injected subcutaneously into scid mice and their in vivo growth behaviour and HPA binding pattern were analysed. Furthermore, the role of HPA binding glycoconjugates concerning the adhesion to endothelial cells in vitro was investigated. Four of the tested cell lines engrafted in the scid mouse model but they showed considerable variations concerning their growth behaviour, their metastatic potential and their HPA binding pattern. HPA inhibited adhesive interactions between cell lines derived from metatstatic sources and tumour necrosis factor (TNF)alpha stimulated endothelial cells. The transplantation of HPA defined breast cancer cell lines into scid mice is a useful animal model for the research of breast cancer and its metastasis. The HPA binding glycoconjugates appear to be associated with adhesive interactions between metastasising tumour cells and endothelial cells.

KW - Acetylgalactosamine

KW - Animals

KW - Breast

KW - Cell Adhesion

KW - Endothelium

KW - Epithelial Cells

KW - Female

KW - Humans

KW - Lectins

KW - Mice

KW - Mice, SCID

KW - Neoplasm Metastasis

KW - Neoplasm Transplantation

KW - Tumor Cells, Cultured

KW - Tumor Necrosis Factor-alpha

U2 - 10.1016/j.canlet.2004.07.046

DO - 10.1016/j.canlet.2004.07.046

M3 - SCORING: Journal article

C2 - 15723724

VL - 219

SP - 233

EP - 242

JO - CANCER LETT

JF - CANCER LETT

SN - 0304-3835

IS - 2

ER -