Homografts and extra-anatomical reconstructions for infected vascular grafts
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Homografts and extra-anatomical reconstructions for infected vascular grafts. / Diener, H; Hellwinkel, Olaf; Carpenter, S; Larena-Avellaneda, A; Debus, E S.
in: J CARDIOVASC SURG, Jahrgang 55, Nr. 2 Suppl 1, 01.04.2014, S. 217-23.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Homografts and extra-anatomical reconstructions for infected vascular grafts
AU - Diener, H
AU - Hellwinkel, Olaf
AU - Carpenter, S
AU - Larena-Avellaneda, A
AU - Debus, E S
PY - 2014/4/1
Y1 - 2014/4/1
N2 - Managing graft infections is a challenge in vascular surgery. The incidence of vascular graft infections varies between 2% and 6%. The number of patients treated by means of implantation of artificial prostheses is constantly growing. The treatment of vascular graft infections remains controversial. This article discusses in-situ repair and the role of extra-anatomic routes. Homografts present the lowest rate of reinfection with acceptable rates of degradation and aneurysm formation. Silvergrafts and synthetic grafts coated with antimicrobials show similar early and late mortality rates, but higher reinfection rates. The outcome extra-anatomic bypass surgery seems to be improved in actual series compared with historical results but their disadvantages (limited patency, higher rate of amputations as well as high rates of reintervention combined with higher early mortality) are obvious.
AB - Managing graft infections is a challenge in vascular surgery. The incidence of vascular graft infections varies between 2% and 6%. The number of patients treated by means of implantation of artificial prostheses is constantly growing. The treatment of vascular graft infections remains controversial. This article discusses in-situ repair and the role of extra-anatomic routes. Homografts present the lowest rate of reinfection with acceptable rates of degradation and aneurysm formation. Silvergrafts and synthetic grafts coated with antimicrobials show similar early and late mortality rates, but higher reinfection rates. The outcome extra-anatomic bypass surgery seems to be improved in actual series compared with historical results but their disadvantages (limited patency, higher rate of amputations as well as high rates of reintervention combined with higher early mortality) are obvious.
KW - Allografts
KW - Amputation
KW - Anti-Bacterial Agents
KW - Bioprosthesis
KW - Blood Vessel Prosthesis
KW - Blood Vessel Prosthesis Implantation
KW - Coated Materials, Biocompatible
KW - Device Removal
KW - Humans
KW - Limb Salvage
KW - Prosthesis Design
KW - Prosthesis-Related Infections
KW - Reconstructive Surgical Procedures
KW - Recurrence
KW - Reoperation
KW - Risk Factors
KW - Treatment Outcome
M3 - SCORING: Journal article
C2 - 24796916
VL - 55
SP - 217
EP - 223
JO - J CARDIOVASC SURG
JF - J CARDIOVASC SURG
SN - 0021-9509
IS - 2 Suppl 1
ER -