High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer.
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High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer. / Klauschen, F; von, Winterfeld M; Stenzinger, A; Sinn, BV; Budczies, J; Kamphues, C; Bahra, M; Wittschieber, D; Weichert, W; Striefler, J; Riess, H; Dietel, M; Denkert, C.
in: HISTOPATHOLOGY, 2012.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer.
AU - Klauschen, F
AU - von, Winterfeld M
AU - Stenzinger, A
AU - Sinn, BV
AU - Budczies, J
AU - Kamphues, C
AU - Bahra, M
AU - Wittschieber, D
AU - Weichert, W
AU - Striefler, J
AU - Riess, H
AU - Dietel, M
AU - Denkert, C
PY - 2012
Y1 - 2012
N2 - Poly-(ADP-ribose)-polymerases (PARPs) act as post-translational modifiers of proteins that are mainly involved in the DNA repair machinery, and have recently been shown to be predictive of pathologically complete remission after chemotherapy in breast cancer. In the pancreas, PARP expression has so far only been studied in inflammatory conditions. Therefore, in this study, we investigated the relevance of PARP in pancreatic cancer.
AB - Poly-(ADP-ribose)-polymerases (PARPs) act as post-translational modifiers of proteins that are mainly involved in the DNA repair machinery, and have recently been shown to be predictive of pathologically complete remission after chemotherapy in breast cancer. In the pancreas, PARP expression has so far only been studied in inflammatory conditions. Therefore, in this study, we investigated the relevance of PARP in pancreatic cancer.
U2 - 10.1111/j.1365-2559.2012.04225.x
DO - 10.1111/j.1365-2559.2012.04225.x
M3 - SCORING: Journal article
C2 - 22384823
JO - HISTOPATHOLOGY
JF - HISTOPATHOLOGY
SN - 0309-0167
ER -