Hepatokardiale Wechselwirkungen: Interaktionen zweier Organsysteme
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Hepatokardiale Wechselwirkungen: Interaktionen zweier Organsysteme. / Horvatits, T; Drolz, A; Rutter, K; Roedl, K; Kluge, S; Fuhrmann, V.
in: MED KLIN-INTENSIVMED, Jahrgang 111, Nr. 5, 06.2016, S. 447-452.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Hepatokardiale Wechselwirkungen: Interaktionen zweier Organsysteme
AU - Horvatits, T
AU - Drolz, A
AU - Rutter, K
AU - Roedl, K
AU - Kluge, S
AU - Fuhrmann, V
PY - 2016/6
Y1 - 2016/6
N2 - Interactions between the hepatic portal and cardiovascular systems are frequently found in patients with liver disease. Cirrhotic cardiomyopathy (CCMP) is defined as reduced cardiac function in patients with liver cirrhosis in the absence of other known causes of cardiac disease. The typical hyperdynamic circulatory state by means of increased cardiac output and reduced systemic vascular resistance may mask left ventricular failure. Portopulmonary hypertension (POPH) is defined as increased pulmonary arterial pressure and the presence of portal hypertension, and is associated with increased mortality. Targeted medical therapies include vasodilators such as prostanoids, endothelin receptor antagonists and phosphodiesterase-5 inhibitors. Hypoxic or ischaemic hepatitis (HH) is defined by a sharp increase of serum aminotransferase levels due to liver cell necrosis as result of cardiac, circulatory or respiratory failure. An overview of these diseases is provided in this article.
AB - Interactions between the hepatic portal and cardiovascular systems are frequently found in patients with liver disease. Cirrhotic cardiomyopathy (CCMP) is defined as reduced cardiac function in patients with liver cirrhosis in the absence of other known causes of cardiac disease. The typical hyperdynamic circulatory state by means of increased cardiac output and reduced systemic vascular resistance may mask left ventricular failure. Portopulmonary hypertension (POPH) is defined as increased pulmonary arterial pressure and the presence of portal hypertension, and is associated with increased mortality. Targeted medical therapies include vasodilators such as prostanoids, endothelin receptor antagonists and phosphodiesterase-5 inhibitors. Hypoxic or ischaemic hepatitis (HH) is defined by a sharp increase of serum aminotransferase levels due to liver cell necrosis as result of cardiac, circulatory or respiratory failure. An overview of these diseases is provided in this article.
U2 - 10.1007/s00063-015-0043-x
DO - 10.1007/s00063-015-0043-x
M3 - SCORING: Zeitschriftenaufsatz
C2 - 26070920
VL - 111
SP - 447
EP - 452
JO - MED KLIN-INTENSIVMED
JF - MED KLIN-INTENSIVMED
SN - 2193-6218
IS - 5
ER -
