Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death
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Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death. / Garland, Jack; Kesha, Kilak; Glenn, Charley; Stables, Simon; Ondruschka, Benjamin; Lohner, Larissa; Tse, Rexson.
in: AM J FOREN MED PATH, Jahrgang 43, Nr. 1, 01.03.2022, S. 18-22.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death
AU - Garland, Jack
AU - Kesha, Kilak
AU - Glenn, Charley
AU - Stables, Simon
AU - Ondruschka, Benjamin
AU - Lohner, Larissa
AU - Tse, Rexson
N1 - Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2022/3/1
Y1 - 2022/3/1
N2 - An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.
AB - An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.
KW - Adult
KW - Arrhythmias, Cardiac
KW - Death, Sudden, Cardiac/etiology
KW - Heart
KW - Heart Failure
KW - Humans
KW - Retrospective Studies
U2 - 10.1097/PAF.0000000000000711
DO - 10.1097/PAF.0000000000000711
M3 - SCORING: Journal article
C2 - 34483235
VL - 43
SP - 18
EP - 22
JO - AM J FOREN MED PATH
JF - AM J FOREN MED PATH
SN - 0195-7910
IS - 1
ER -