Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death

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Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death. / Garland, Jack; Kesha, Kilak; Glenn, Charley; Stables, Simon; Ondruschka, Benjamin; Lohner, Larissa; Tse, Rexson.

in: AM J FOREN MED PATH, Jahrgang 43, Nr. 1, 01.03.2022, S. 18-22.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{c84e1b334f6e484097c902939450f728,
title = "Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death",
abstract = "An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.",
keywords = "Adult, Arrhythmias, Cardiac, Death, Sudden, Cardiac/etiology, Heart, Heart Failure, Humans, Retrospective Studies",
author = "Jack Garland and Kilak Kesha and Charley Glenn and Simon Stables and Benjamin Ondruschka and Larissa Lohner and Rexson Tse",
note = "Copyright {\textcopyright} 2021 Wolters Kluwer Health, Inc. All rights reserved.",
year = "2022",
month = mar,
day = "1",
doi = "10.1097/PAF.0000000000000711",
language = "English",
volume = "43",
pages = "18--22",
journal = "AM J FOREN MED PATH",
issn = "0195-7910",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

RIS

TY - JOUR

T1 - Heart weight is an independent factor associated with, but is a poor predictor for, sudden cardiac death

AU - Garland, Jack

AU - Kesha, Kilak

AU - Glenn, Charley

AU - Stables, Simon

AU - Ondruschka, Benjamin

AU - Lohner, Larissa

AU - Tse, Rexson

N1 - Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

PY - 2022/3/1

Y1 - 2022/3/1

N2 - An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.

AB - An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.

KW - Adult

KW - Arrhythmias, Cardiac

KW - Death, Sudden, Cardiac/etiology

KW - Heart

KW - Heart Failure

KW - Humans

KW - Retrospective Studies

U2 - 10.1097/PAF.0000000000000711

DO - 10.1097/PAF.0000000000000711

M3 - SCORING: Journal article

C2 - 34483235

VL - 43

SP - 18

EP - 22

JO - AM J FOREN MED PATH

JF - AM J FOREN MED PATH

SN - 0195-7910

IS - 1

ER -