Health-related quality of life in autoimmune hepatitis

TY - JOUR

T1 - Health-related quality of life in autoimmune hepatitis

AU - Snijders, Romée Jalm

AU - Milkiewicz, Piotr

AU - Schramm, Christoph

AU - Gevers, Tom Jg

N1 - ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

PY - 2021/11/27

Y1 - 2021/11/27

N2 - Autoimmune hepatitis (AIH) is a severe chronic autoimmune disease and has a significant impact on the patient's quality of life, in particular regarding psychological problems such as anxiety and depression. Consistent evidence on which patient-related, disease-related or physician-related factors cause health-related quality of life (HRQoL) impairment in patients with AIH is lacking. Current studies on HRQoL in AIH are mainly single-centered, comprising small numbers of patients, and difficult to compare because of the use of different questionnaires, patient populations, and cutoff values. Literature in the pediatric field is sparse, but suggests that children/adolescents with AIH have a lower HRQoL. Knowledge of HRQoL and cohesive factors in AIH are important to improve healthcare for AIH patients, for example by developing an AIH-specific chronic healthcare model. By recognizing the importance of quality of life beyond the concept of biochemical and histological remission, clinicians allow us to seek enhancements and possible interventions in the management of AIH, aiming at improved health.

AB - Autoimmune hepatitis (AIH) is a severe chronic autoimmune disease and has a significant impact on the patient's quality of life, in particular regarding psychological problems such as anxiety and depression. Consistent evidence on which patient-related, disease-related or physician-related factors cause health-related quality of life (HRQoL) impairment in patients with AIH is lacking. Current studies on HRQoL in AIH are mainly single-centered, comprising small numbers of patients, and difficult to compare because of the use of different questionnaires, patient populations, and cutoff values. Literature in the pediatric field is sparse, but suggests that children/adolescents with AIH have a lower HRQoL. Knowledge of HRQoL and cohesive factors in AIH are important to improve healthcare for AIH patients, for example by developing an AIH-specific chronic healthcare model. By recognizing the importance of quality of life beyond the concept of biochemical and histological remission, clinicians allow us to seek enhancements and possible interventions in the management of AIH, aiming at improved health.

U2 - 10.4254/wjh.v13.i11.1642

DO - 10.4254/wjh.v13.i11.1642

M3 - SCORING: Review article

C2 - 34904034

VL - 13

SP - 1642

EP - 1652

JO - WORLD J HEPATOL

JF - WORLD J HEPATOL

SN - 1948-5182

IS - 11

ER -