Hautersatzverfahren bei chronischen Wunden
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Hautersatzverfahren bei chronischen Wunden. / Ziegler, U E; Debus, E S; Keller, H P; Thiede, A.
in: ZBL CHIR, Jahrgang 126 Suppl 1, 2001, S. 71-74.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Hautersatzverfahren bei chronischen Wunden
AU - Ziegler, U E
AU - Debus, E S
AU - Keller, H P
AU - Thiede, A
PY - 2001
Y1 - 2001
N2 - Skin substitutes in chronic wounds. There is a large demand for skin substitutes for the coverage of chronic wounds. Due to a intensive and local wound treatment the impaired dermal and epidermal repair still remains a major problem. Known treatmentes as split-skin-, reverdin- and pinch grafts make a sufficient and solid wound closure possible. However in such procedures the take rate of grafting often failes. The graft healing is increased with combined mesh-graft and vacuum-sealing technique. Temporary and permanent skin substitutes extend the spectrum in closure of chronic defects. Sheets and single cell suspensions of keratinocytes are available for clincial treatments. First clinical results with autologous keratinocyte transplantation are described. In the future approaches in gen therapy becomes more and more important for skin substitutes.
AB - Skin substitutes in chronic wounds. There is a large demand for skin substitutes for the coverage of chronic wounds. Due to a intensive and local wound treatment the impaired dermal and epidermal repair still remains a major problem. Known treatmentes as split-skin-, reverdin- and pinch grafts make a sufficient and solid wound closure possible. However in such procedures the take rate of grafting often failes. The graft healing is increased with combined mesh-graft and vacuum-sealing technique. Temporary and permanent skin substitutes extend the spectrum in closure of chronic defects. Sheets and single cell suspensions of keratinocytes are available for clincial treatments. First clinical results with autologous keratinocyte transplantation are described. In the future approaches in gen therapy becomes more and more important for skin substitutes.
KW - Chronic Disease
KW - Humans
KW - Keratinocytes/transplantation
KW - Skin Transplantation
KW - Skin, Artificial
KW - Tissue Engineering
KW - Transplantation, Autologous
KW - Wounds and Injuries/surgery
U2 - 10.1055/s-2001-19205
DO - 10.1055/s-2001-19205
M3 - SCORING: Review
C2 - 11819178
VL - 126 Suppl 1
SP - 71
EP - 74
JO - ZBL CHIR
JF - ZBL CHIR
SN - 0044-409X
ER -