Glycans and neural cell interactions.
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Glycans and neural cell interactions. / Kleene, Ralf; Schachner, Melitta.
in: NAT REV NEUROSCI, Jahrgang 5, Nr. 3, 3, 2004, S. 195-208.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Glycans and neural cell interactions.
AU - Kleene, Ralf
AU - Schachner, Melitta
PY - 2004
Y1 - 2004
N2 - Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular meshwork at the cell surface and in the extracellular matrix. The tremendous structural diversity of glycan chains allows for immense combinatorial possibilities that might underlie the fine-tuning of cell-cell and cell-matrix interactions.
AB - Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular meshwork at the cell surface and in the extracellular matrix. The tremendous structural diversity of glycan chains allows for immense combinatorial possibilities that might underlie the fine-tuning of cell-cell and cell-matrix interactions.
KW - Animals
KW - Humans
KW - Amino Acid Sequence
KW - Molecular Sequence Data
KW - Sequence Alignment
KW - Neuronal Plasticity
KW - Carbohydrate Sequence
KW - Extracellular Matrix/metabolism
KW - Carbohydrate Conformation
KW - Cell Communication
KW - Circadian Rhythm/physiology
KW - Nervous System Diseases/metabolism
KW - Neural Cell Adhesion Molecules/genetics/metabolism
KW - Neurons/chemistry/physiology
KW - Polysaccharides/chemistry/metabolism
KW - Animals
KW - Humans
KW - Amino Acid Sequence
KW - Molecular Sequence Data
KW - Sequence Alignment
KW - Neuronal Plasticity
KW - Carbohydrate Sequence
KW - Extracellular Matrix/metabolism
KW - Carbohydrate Conformation
KW - Cell Communication
KW - Circadian Rhythm/physiology
KW - Nervous System Diseases/metabolism
KW - Neural Cell Adhesion Molecules/genetics/metabolism
KW - Neurons/chemistry/physiology
KW - Polysaccharides/chemistry/metabolism
M3 - SCORING: Journal article
VL - 5
SP - 195
EP - 208
JO - NAT REV NEUROSCI
JF - NAT REV NEUROSCI
SN - 1471-003X
IS - 3
M1 - 3
ER -