Glomerulonephritis therapy: is there a role for green tea?
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Glomerulonephritis therapy: is there a role for green tea? / Turner, Jan Eric.
in: KIDNEY INT, Jahrgang 80, Nr. 6, 6, 01.09.2011, S. 563-564.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Glomerulonephritis therapy: is there a role for green tea?
AU - Turner, Jan Eric
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Rapidly progressive glomerulonephritis is the most aggressive form of glomerulonephritis with the worst prognosis. The current unspecific immunosuppressive therapy with corticosteroids and cytotoxic agents is often complicated by severe side effects. Peng and colleagues studied the therapeutic potential of the green tea component (-)-epigallocatechin-3-gallate (EGCG) in a murine model of immune-mediated glomerulonephritis. Their results indicate that EGCG treatment ameliorates renal inflammation, tissue damage, and loss of renal function and might therefore represent a novel therapeutic approach for human glomerulonephritis.
AB - Rapidly progressive glomerulonephritis is the most aggressive form of glomerulonephritis with the worst prognosis. The current unspecific immunosuppressive therapy with corticosteroids and cytotoxic agents is often complicated by severe side effects. Peng and colleagues studied the therapeutic potential of the green tea component (-)-epigallocatechin-3-gallate (EGCG) in a murine model of immune-mediated glomerulonephritis. Their results indicate that EGCG treatment ameliorates renal inflammation, tissue damage, and loss of renal function and might therefore represent a novel therapeutic approach for human glomerulonephritis.
KW - Animals
KW - Male
KW - Anti-Glomerular Basement Membrane Disease/prevention & control
KW - Catechin/analogs & derivatives/pharmacology
KW - Tea/chemistry
KW - Animals
KW - Male
KW - Anti-Glomerular Basement Membrane Disease/prevention & control
KW - Catechin/analogs & derivatives/pharmacology
KW - Tea/chemistry
U2 - 10.1038/ki.2011.173
DO - 10.1038/ki.2011.173
M3 - SCORING: Journal article
C2 - 21878951
VL - 80
SP - 563
EP - 564
JO - KIDNEY INT
JF - KIDNEY INT
SN - 0085-2538
IS - 6
M1 - 6
ER -