Glomerulonephritis therapy: is there a role for green tea?

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Glomerulonephritis therapy: is there a role for green tea? / Turner, Jan Eric.

in: KIDNEY INT, Jahrgang 80, Nr. 6, 6, 01.09.2011, S. 563-564.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{b3d21cdfe7af4e099967952edfc322aa,
title = "Glomerulonephritis therapy: is there a role for green tea?",
abstract = "Rapidly progressive glomerulonephritis is the most aggressive form of glomerulonephritis with the worst prognosis. The current unspecific immunosuppressive therapy with corticosteroids and cytotoxic agents is often complicated by severe side effects. Peng and colleagues studied the therapeutic potential of the green tea component (-)-epigallocatechin-3-gallate (EGCG) in a murine model of immune-mediated glomerulonephritis. Their results indicate that EGCG treatment ameliorates renal inflammation, tissue damage, and loss of renal function and might therefore represent a novel therapeutic approach for human glomerulonephritis.",
keywords = "Animals, Male, Anti-Glomerular Basement Membrane Disease/*prevention & control, Catechin/*analogs & derivatives/pharmacology, Tea/*chemistry, Animals, Male, Anti-Glomerular Basement Membrane Disease/*prevention & control, Catechin/*analogs & derivatives/pharmacology, Tea/*chemistry",
author = "Turner, {Jan Eric}",
year = "2011",
month = sep,
day = "1",
doi = "10.1038/ki.2011.173",
language = "English",
volume = "80",
pages = "563--564",
journal = "KIDNEY INT",
issn = "0085-2538",
publisher = "NATURE PUBLISHING GROUP",
number = "6",

}

RIS

TY - JOUR

T1 - Glomerulonephritis therapy: is there a role for green tea?

AU - Turner, Jan Eric

PY - 2011/9/1

Y1 - 2011/9/1

N2 - Rapidly progressive glomerulonephritis is the most aggressive form of glomerulonephritis with the worst prognosis. The current unspecific immunosuppressive therapy with corticosteroids and cytotoxic agents is often complicated by severe side effects. Peng and colleagues studied the therapeutic potential of the green tea component (-)-epigallocatechin-3-gallate (EGCG) in a murine model of immune-mediated glomerulonephritis. Their results indicate that EGCG treatment ameliorates renal inflammation, tissue damage, and loss of renal function and might therefore represent a novel therapeutic approach for human glomerulonephritis.

AB - Rapidly progressive glomerulonephritis is the most aggressive form of glomerulonephritis with the worst prognosis. The current unspecific immunosuppressive therapy with corticosteroids and cytotoxic agents is often complicated by severe side effects. Peng and colleagues studied the therapeutic potential of the green tea component (-)-epigallocatechin-3-gallate (EGCG) in a murine model of immune-mediated glomerulonephritis. Their results indicate that EGCG treatment ameliorates renal inflammation, tissue damage, and loss of renal function and might therefore represent a novel therapeutic approach for human glomerulonephritis.

KW - Animals

KW - Male

KW - Anti-Glomerular Basement Membrane Disease/prevention & control

KW - Catechin/analogs & derivatives/pharmacology

KW - Tea/chemistry

KW - Animals

KW - Male

KW - Anti-Glomerular Basement Membrane Disease/prevention & control

KW - Catechin/analogs & derivatives/pharmacology

KW - Tea/chemistry

U2 - 10.1038/ki.2011.173

DO - 10.1038/ki.2011.173

M3 - SCORING: Journal article

C2 - 21878951

VL - 80

SP - 563

EP - 564

JO - KIDNEY INT

JF - KIDNEY INT

SN - 0085-2538

IS - 6

M1 - 6

ER -