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Glioma stem cells as a target for treatment.

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Glioma stem cells as a target for treatment. / Lamszus, Katrin; Günther, Hauke.

in: TARGET ONCOL, Jahrgang 5, Nr. 3, 3, 2010, S. 211-215.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lamszus, K & Günther, H 2010, 'Glioma stem cells as a target for treatment.', TARGET ONCOL, Jg. 5, Nr. 3, 3, S. 211-215. <http://www.ncbi.nlm.nih.gov/pubmed/20737293?dopt=Citation>

APA

Lamszus, K., & Günther, H. (2010). Glioma stem cells as a target for treatment. TARGET ONCOL, 5(3), 211-215. [3]. http://www.ncbi.nlm.nih.gov/pubmed/20737293?dopt=Citation

Vancouver

Lamszus K, Günther H. Glioma stem cells as a target for treatment. TARGET ONCOL. 2010;5(3):211-215. 3.

Bibtex

@article{99fcedfd582b4f109a98f0862aa22fc8,
title = "Glioma stem cells as a target for treatment.",
abstract = "Glioma cells with stem cell-like properties represent a minor subfraction of the total tumor cell population. These cells are highly chemo- and radioresistent and are held responsible for the inevitable recurrence of malignant gliomas. This review summarizes current strategies for targeting putative glioma stem cells. Target definition approaches comprise extrapolation and adaptation of therapies from general oncology, target identification by correlative molecular genetic analyses, and dedicated target discovery research. Targeting strategies include inhibition of tumor-specific signaling pathways, enhancement of tumor cell differentiation, radiosensitization, indirect targeting of the tumor stem cell niche, oncolytic virotherapy, and adhesion molecule blockade.",
author = "Katrin Lamszus and Hauke G{\"u}nther",
year = "2010",
language = "Deutsch",
volume = "5",
pages = "211--215",
journal = "TARGET ONCOL",
issn = "1776-2596",
publisher = "Springer Paris",
number = "3",

}

RIS

TY - JOUR

T1 - Glioma stem cells as a target for treatment.

AU - Lamszus, Katrin

AU - Günther, Hauke

PY - 2010

Y1 - 2010

N2 - Glioma cells with stem cell-like properties represent a minor subfraction of the total tumor cell population. These cells are highly chemo- and radioresistent and are held responsible for the inevitable recurrence of malignant gliomas. This review summarizes current strategies for targeting putative glioma stem cells. Target definition approaches comprise extrapolation and adaptation of therapies from general oncology, target identification by correlative molecular genetic analyses, and dedicated target discovery research. Targeting strategies include inhibition of tumor-specific signaling pathways, enhancement of tumor cell differentiation, radiosensitization, indirect targeting of the tumor stem cell niche, oncolytic virotherapy, and adhesion molecule blockade.

AB - Glioma cells with stem cell-like properties represent a minor subfraction of the total tumor cell population. These cells are highly chemo- and radioresistent and are held responsible for the inevitable recurrence of malignant gliomas. This review summarizes current strategies for targeting putative glioma stem cells. Target definition approaches comprise extrapolation and adaptation of therapies from general oncology, target identification by correlative molecular genetic analyses, and dedicated target discovery research. Targeting strategies include inhibition of tumor-specific signaling pathways, enhancement of tumor cell differentiation, radiosensitization, indirect targeting of the tumor stem cell niche, oncolytic virotherapy, and adhesion molecule blockade.

M3 - SCORING: Zeitschriftenaufsatz

VL - 5

SP - 211

EP - 215

JO - TARGET ONCOL

JF - TARGET ONCOL

SN - 1776-2596

IS - 3

M1 - 3

ER -