German ablation registry: Cryoballoon vs. radiofrequency ablation in paroxysmal atrial fibrillation--One-year outcome data
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German ablation registry: Cryoballoon vs. radiofrequency ablation in paroxysmal atrial fibrillation--One-year outcome data. / Schmidt, Martin; Dorwarth, Uwe; Andresen, Dietrich; Brachmann, Johannes; Kuck, Karlheinz; Kuniss, Malte; Willems, Stephan; Deneke, Thomas; Tebbenjohanns, Jürgen; Gerds-Li, Jin-Hong; Spitzer, Stefan; Senges, Jochen; Hochadel, Matthias; Hoffmann, Ellen.
in: HEART RHYTHM, Jahrgang 13, Nr. 4, 04.2016, S. 836-844.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - German ablation registry: Cryoballoon vs. radiofrequency ablation in paroxysmal atrial fibrillation--One-year outcome data
AU - Schmidt, Martin
AU - Dorwarth, Uwe
AU - Andresen, Dietrich
AU - Brachmann, Johannes
AU - Kuck, Karlheinz
AU - Kuniss, Malte
AU - Willems, Stephan
AU - Deneke, Thomas
AU - Tebbenjohanns, Jürgen
AU - Gerds-Li, Jin-Hong
AU - Spitzer, Stefan
AU - Senges, Jochen
AU - Hochadel, Matthias
AU - Hoffmann, Ellen
N1 - Copyright © 2016 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
PY - 2016/4
Y1 - 2016/4
N2 - BACKGROUND: Although radiofrequency (RF) ablation has long been the standard of care for atrial fibrillation (AF) ablation, cryoballoon technology has emerged as a feasible approach with promising results. Prospective multicenter registry data referring to both ablation technologies in AF ablation are lacking so far.OBJECTIVE: The purpose of this study was to report data from the German ablation registry with respect to efficacy and safety in pulmonary vein ablation with different energy sources for paroxysmal AF after 1-year follow-up.METHODS: A total of 2306 patients with symptomatic paroxysmal AF from the German ablation registry were included in this analysis. The cohort was divided into two groups according to the ablation energy source used: cryoballoon and RF ablation. MACCE was defined as a combination of death, myocardial infarction, or stroke.RESULTS: AF recurrence rate after a single ablation procedure at 1 year follow-up was not significantly different between the two groups (45.8% after cryoablation and 45.4% after RF ablation, P = .87). Also, the rate of patients without AF recurrence and free of antiarrhythmic drug at 12-month follow-up was similar (cryoablation 44.2% and RF 41.4%, P = .25). MACCE occurred with an incidence of 0.7% within 500 days after cryoablation and 1.4% after RF ablation (P = .30). Persistent phrenic nerve palsy was more common after cryoablation compared to RF ablation (1.1% vs. 0.3%, P <.05).CONCLUSION: AF recurrence rate at 1-year follow-up was similar in RF ablation compared to cryoablation, whereas the spectrum and relevance of complications were significantly different between the two ablation methods. This finding might influence the choice of ablation method offered to the individual paroxysmal AF patient.
AB - BACKGROUND: Although radiofrequency (RF) ablation has long been the standard of care for atrial fibrillation (AF) ablation, cryoballoon technology has emerged as a feasible approach with promising results. Prospective multicenter registry data referring to both ablation technologies in AF ablation are lacking so far.OBJECTIVE: The purpose of this study was to report data from the German ablation registry with respect to efficacy and safety in pulmonary vein ablation with different energy sources for paroxysmal AF after 1-year follow-up.METHODS: A total of 2306 patients with symptomatic paroxysmal AF from the German ablation registry were included in this analysis. The cohort was divided into two groups according to the ablation energy source used: cryoballoon and RF ablation. MACCE was defined as a combination of death, myocardial infarction, or stroke.RESULTS: AF recurrence rate after a single ablation procedure at 1 year follow-up was not significantly different between the two groups (45.8% after cryoablation and 45.4% after RF ablation, P = .87). Also, the rate of patients without AF recurrence and free of antiarrhythmic drug at 12-month follow-up was similar (cryoablation 44.2% and RF 41.4%, P = .25). MACCE occurred with an incidence of 0.7% within 500 days after cryoablation and 1.4% after RF ablation (P = .30). Persistent phrenic nerve palsy was more common after cryoablation compared to RF ablation (1.1% vs. 0.3%, P <.05).CONCLUSION: AF recurrence rate at 1-year follow-up was similar in RF ablation compared to cryoablation, whereas the spectrum and relevance of complications were significantly different between the two ablation methods. This finding might influence the choice of ablation method offered to the individual paroxysmal AF patient.
KW - Aged
KW - Atrial Fibrillation/physiopathology
KW - Catheter Ablation/methods
KW - Cryosurgery/methods
KW - Disease-Free Survival
KW - Electrocardiography
KW - Female
KW - Follow-Up Studies
KW - Germany/epidemiology
KW - Heart Conduction System/physiopathology
KW - Humans
KW - Incidence
KW - Male
KW - Middle Aged
KW - Postoperative Complications/epidemiology
KW - Prognosis
KW - Prospective Studies
KW - Recurrence
KW - Registries
KW - Survival Rate/trends
KW - Tachycardia, Paroxysmal/physiopathology
KW - Treatment Outcome
U2 - 10.1016/j.hrthm.2015.12.007
DO - 10.1016/j.hrthm.2015.12.007
M3 - SCORING: Journal article
C2 - 26681608
VL - 13
SP - 836
EP - 844
JO - HEART RHYTHM
JF - HEART RHYTHM
SN - 1547-5271
IS - 4
ER -