Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.
Beteiligte Einrichtungen
Abstract
Late Onset Alzheimer's disease (LOAD) is the leading cause of dementia. Recent large genome-wide association studies (GWAS) identified the first strongly supported LOAD susceptibility genes since the discovery of the involvement of APOE in the early 1990s. We have now exploited these GWAS datasets to uncover key LOAD pathophysiological processes.
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 11 |
| ISSN | 1932-6203 |
| DOIs | |
| Status | Veröffentlicht - 2010 |
| pubmed | 21085570 |
|---|
