Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel

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Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel. / Freytag, A; Quinzler, R; Freitag, M; Bickel, H; Fuchs, A; Hansen, H; Hoefels, S; König, H-H; Mergenthal, K; Riedel-Heller, S G; Schön, G; Weyerer, S; Wegscheider, K; Scherer, M; Bussche van den, Hendrik; Haefeli, W E; Gensichen, J.

in: SCHMERZ, Jahrgang 28, Nr. 2, 01.04.2014, S. 175-82.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Freytag, A, Quinzler, R, Freitag, M, Bickel, H, Fuchs, A, Hansen, H, Hoefels, S, König, H-H, Mergenthal, K, Riedel-Heller, SG, Schön, G, Weyerer, S, Wegscheider, K, Scherer, M, Bussche van den, H, Haefeli, WE & Gensichen, J 2014, 'Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel', SCHMERZ, Jg. 28, Nr. 2, S. 175-82. https://doi.org/10.1007/s00482-014-1415-5

APA

Freytag, A., Quinzler, R., Freitag, M., Bickel, H., Fuchs, A., Hansen, H., Hoefels, S., König, H-H., Mergenthal, K., Riedel-Heller, S. G., Schön, G., Weyerer, S., Wegscheider, K., Scherer, M., Bussche van den, H., Haefeli, W. E., & Gensichen, J. (2014). Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel. SCHMERZ, 28(2), 175-82. https://doi.org/10.1007/s00482-014-1415-5

Vancouver

Bibtex

@article{a5a363a03f764303afb2b143e4d9de62,
title = "Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel",
abstract = "BACKGROUND AND AIM: We investigated the use of prescription and non-prescription (over-the-counter, OTC) analgesics and the associated risks in elderly patients with multiple morbidities.METHODS: Pain medication use was evaluated from the baseline data (2008/2009) of the MultiCare cohort enrolling elderly patients with multiple morbidities who were treated by primary care physicians (trial registration: ISRCTN89818205). We considered opioids (N02A), other analgesics, and antipyretics (N02B) as well as nonsteroidal anti-inflammatory drugs (NSAIDs; M01A). OTC use, duplicate prescription, dosages, and interactions were examined for acetylsalicylic acid, diclofenac, (dex)ibuprofen, naproxen, and acetaminophen.RESULTS: Of 3,189 patients with multiple morbidities aged 65-85 years, 1,170 patients reported to have taken at least one prescription or non-prescription analgesic within the last 3 months (36.7 %). Of these, 289 patients (24.7 % of 1,170) took at least one OTC analgesic. Duplicate prescription was observed in 86 cases; 15 of these cases took the analgesics regularly. In two cases, the maximum daily dose of diclofenac was exceeded due to duplicate prescription. In 235 cases, patients concurrently took a drug with a potentially clinically relevant interaction. In 43 cases (18.3 % of 235) an OTC analgesic, usually ibuprofen, was involved.DISCUSSION: About one third of the elderly patients took analgesics regularly or as needed. Despite the relatively high use of OTC analgesics, the proportions of duplicate prescription, medication overdoses, and adverse interactions due to OTC products was low.",
author = "A Freytag and R Quinzler and M Freitag and H Bickel and A Fuchs and H Hansen and S Hoefels and H-H K{\"o}nig and K Mergenthal and Riedel-Heller, {S G} and G Sch{\"o}n and S Weyerer and K Wegscheider and M Scherer and {Bussche van den}, Hendrik and Haefeli, {W E} and J Gensichen",
note = "wegscheider allgemeinmedizin laut pubikation ?!",
year = "2014",
month = apr,
day = "1",
doi = "10.1007/s00482-014-1415-5",
language = "Deutsch",
volume = "28",
pages = "175--82",
journal = "SCHMERZ",
issn = "0932-433X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel

AU - Freytag, A

AU - Quinzler, R

AU - Freitag, M

AU - Bickel, H

AU - Fuchs, A

AU - Hansen, H

AU - Hoefels, S

AU - König, H-H

AU - Mergenthal, K

AU - Riedel-Heller, S G

AU - Schön, G

AU - Weyerer, S

AU - Wegscheider, K

AU - Scherer, M

AU - Bussche van den, Hendrik

AU - Haefeli, W E

AU - Gensichen, J

N1 - wegscheider allgemeinmedizin laut pubikation ?!

PY - 2014/4/1

Y1 - 2014/4/1

N2 - BACKGROUND AND AIM: We investigated the use of prescription and non-prescription (over-the-counter, OTC) analgesics and the associated risks in elderly patients with multiple morbidities.METHODS: Pain medication use was evaluated from the baseline data (2008/2009) of the MultiCare cohort enrolling elderly patients with multiple morbidities who were treated by primary care physicians (trial registration: ISRCTN89818205). We considered opioids (N02A), other analgesics, and antipyretics (N02B) as well as nonsteroidal anti-inflammatory drugs (NSAIDs; M01A). OTC use, duplicate prescription, dosages, and interactions were examined for acetylsalicylic acid, diclofenac, (dex)ibuprofen, naproxen, and acetaminophen.RESULTS: Of 3,189 patients with multiple morbidities aged 65-85 years, 1,170 patients reported to have taken at least one prescription or non-prescription analgesic within the last 3 months (36.7 %). Of these, 289 patients (24.7 % of 1,170) took at least one OTC analgesic. Duplicate prescription was observed in 86 cases; 15 of these cases took the analgesics regularly. In two cases, the maximum daily dose of diclofenac was exceeded due to duplicate prescription. In 235 cases, patients concurrently took a drug with a potentially clinically relevant interaction. In 43 cases (18.3 % of 235) an OTC analgesic, usually ibuprofen, was involved.DISCUSSION: About one third of the elderly patients took analgesics regularly or as needed. Despite the relatively high use of OTC analgesics, the proportions of duplicate prescription, medication overdoses, and adverse interactions due to OTC products was low.

AB - BACKGROUND AND AIM: We investigated the use of prescription and non-prescription (over-the-counter, OTC) analgesics and the associated risks in elderly patients with multiple morbidities.METHODS: Pain medication use was evaluated from the baseline data (2008/2009) of the MultiCare cohort enrolling elderly patients with multiple morbidities who were treated by primary care physicians (trial registration: ISRCTN89818205). We considered opioids (N02A), other analgesics, and antipyretics (N02B) as well as nonsteroidal anti-inflammatory drugs (NSAIDs; M01A). OTC use, duplicate prescription, dosages, and interactions were examined for acetylsalicylic acid, diclofenac, (dex)ibuprofen, naproxen, and acetaminophen.RESULTS: Of 3,189 patients with multiple morbidities aged 65-85 years, 1,170 patients reported to have taken at least one prescription or non-prescription analgesic within the last 3 months (36.7 %). Of these, 289 patients (24.7 % of 1,170) took at least one OTC analgesic. Duplicate prescription was observed in 86 cases; 15 of these cases took the analgesics regularly. In two cases, the maximum daily dose of diclofenac was exceeded due to duplicate prescription. In 235 cases, patients concurrently took a drug with a potentially clinically relevant interaction. In 43 cases (18.3 % of 235) an OTC analgesic, usually ibuprofen, was involved.DISCUSSION: About one third of the elderly patients took analgesics regularly or as needed. Despite the relatively high use of OTC analgesics, the proportions of duplicate prescription, medication overdoses, and adverse interactions due to OTC products was low.

U2 - 10.1007/s00482-014-1415-5

DO - 10.1007/s00482-014-1415-5

M3 - SCORING: Zeitschriftenaufsatz

C2 - 24718747

VL - 28

SP - 175

EP - 182

JO - SCHMERZ

JF - SCHMERZ

SN - 0932-433X

IS - 2

ER -