Future trials of endovascular mechanical recanalisation therapy in acute ischemic stroke patients: a position paper endorsed by ESMINT and ESNR : part I: Current situation and major research questions.
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Future trials of endovascular mechanical recanalisation therapy in acute ischemic stroke patients: a position paper endorsed by ESMINT and ESNR : part I: Current situation and major research questions. / Fiehler, Jens; Söderman, Michael; Turjman, Francis; White, Philip M; Bakke, Søren Jacob; Mangiafico, Salvatore; von Kummer, Rüdiger; Muto, Mario; Cognard, Christophe; Gralla, Jan.
in: NEURORADIOLOGY, Jahrgang 54, Nr. 12, 12, 2012, S. 1293-1301.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Future trials of endovascular mechanical recanalisation therapy in acute ischemic stroke patients: a position paper endorsed by ESMINT and ESNR : part I: Current situation and major research questions.
AU - Fiehler, Jens
AU - Söderman, Michael
AU - Turjman, Francis
AU - White, Philip M
AU - Bakke, Søren Jacob
AU - Mangiafico, Salvatore
AU - von Kummer, Rüdiger
AU - Muto, Mario
AU - Cognard, Christophe
AU - Gralla, Jan
PY - 2012
Y1 - 2012
N2 - A new era of stroke treatment may have begun with mechanical thrombectomy (MT) by fully deployed closed-cell self-expanding stents (stent-triever). Multiple case series and the first randomised controlled trials (RCTs) have now been published. More studies are under way involving large numbers of patients, which in turn has resulted in less strict "pragmatic" study protocols. Problems with current trials include a lack of standardisation in the conduct of the recanalisation procedure, the definition of primary endpoints such as the grade of arterial recanalisation and tissue reperfusion, and the post-surgical care provided. In Part 1 of this two part series, we outline the current situation and the major research questions.
AB - A new era of stroke treatment may have begun with mechanical thrombectomy (MT) by fully deployed closed-cell self-expanding stents (stent-triever). Multiple case series and the first randomised controlled trials (RCTs) have now been published. More studies are under way involving large numbers of patients, which in turn has resulted in less strict "pragmatic" study protocols. Problems with current trials include a lack of standardisation in the conduct of the recanalisation procedure, the definition of primary endpoints such as the grade of arterial recanalisation and tissue reperfusion, and the post-surgical care provided. In Part 1 of this two part series, we outline the current situation and the major research questions.
KW - Humans
KW - Forecasting
KW - Europe
KW - Societies, Medical
KW - Technology Assessment, Biomedical
KW - Stents
KW - Neuroimaging
KW - Radiography, Interventional
KW - Clinical Trials as Topic/standards
KW - Research Design/standards
KW - Thrombectomy/instrumentation/methods
KW - Brain Ischemia/diagnosis/therapy
KW - Intracranial Thrombosis/diagnosis/therapy
KW - Stroke/diagnosis/therapy
KW - Humans
KW - Forecasting
KW - Europe
KW - Societies, Medical
KW - Technology Assessment, Biomedical
KW - Stents
KW - Neuroimaging
KW - Radiography, Interventional
KW - Clinical Trials as Topic/standards
KW - Research Design/standards
KW - Thrombectomy/instrumentation/methods
KW - Brain Ischemia/diagnosis/therapy
KW - Intracranial Thrombosis/diagnosis/therapy
KW - Stroke/diagnosis/therapy
M3 - SCORING: Journal article
VL - 54
SP - 1293
EP - 1301
JO - NEURORADIOLOGY
JF - NEURORADIOLOGY
SN - 0028-3940
IS - 12
M1 - 12
ER -
