From podocyte biology to novel cures for glomerular disease

Elena Torban; Fabian Braun; Nicola Wanner; Tomoko Takano; Paul R Goodyer; Rachel Lennon; Pierre Ronco; Andrey V Cybulsky; Tobias B Huber

doi:10.1016/j.kint.2019.05.015

From podocyte biology to novel cures for glomerular disease

Standard

From podocyte biology to novel cures for glomerular disease. / Torban, Elena; Braun, Fabian ; Wanner, Nicola; Takano, Tomoko; Goodyer, Paul R; Lennon, Rachel; Ronco, Pierre; Cybulsky, Andrey V; Huber, Tobias B.

in: KIDNEY INT, Jahrgang 96, Nr. 4, 10.2019, S. 850-861.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Torban, E, Braun, F , Wanner, N, Takano, T, Goodyer, PR, Lennon, R, Ronco, P, Cybulsky, AV & Huber, TB 2019, 'From podocyte biology to novel cures for glomerular disease', KIDNEY INT, Jg. 96, Nr. 4, S. 850-861. https://doi.org/10.1016/j.kint.2019.05.015

APA

Torban, E., Braun, F., Wanner, N., Takano, T., Goodyer, P. R., Lennon, R., Ronco, P., Cybulsky, A. V., & Huber, T. B. (2019). From podocyte biology to novel cures for glomerular disease. KIDNEY INT, 96(4), 850-861. https://doi.org/10.1016/j.kint.2019.05.015

Vancouver

Torban E, Braun F , Wanner N, Takano T, Goodyer PR, Lennon R et al. From podocyte biology to novel cures for glomerular disease. KIDNEY INT. 2019 Okt;96(4):850-861. https://doi.org/10.1016/j.kint.2019.05.015

Bibtex

@article{10af90d2abcc4fdc931906b88b7792f1,

title = "From podocyte biology to novel cures for glomerular disease",

abstract = "The podocyte is a key component of the glomerular filtration barrier. Podocyte dysfunction is central to the underlying pathophysiology of many common glomerular diseases, including diabetic nephropathy, glomerulonephritis and genetic forms of nephrotic syndrome. Collectively, these conditions affect millions of people worldwide, and account for the majority of kidney diseases requiring dialysis and transplantation. The 12th International Podocyte Conference was held in Montreal, Canada from May 30 to June 2, 2018. The primary aim of this conference was to bring together nephrologists, clinician scientists, basic scientists and their trainees from all over the world to present their research and to establish networks with the common goal of developing new therapies for glomerular diseases based on the latest advances in podocyte biology. This review briefly highlights recent advances made in understanding podocyte structure and metabolism, experimental systems in which to study podocytes and glomerular disease, disease mediators, genetic and immune origins of glomerulopathies, and the development of novel therapeutic agents to protect podocyte and glomerular injury.",

author = "Elena Torban and Fabian Braun and Nicola Wanner and Tomoko Takano and Goodyer, {Paul R} and Rachel Lennon and Pierre Ronco and Cybulsky, {Andrey V} and Huber, {Tobias B}",

note = "Copyright {\textcopyright} 2019. Published by Elsevier Inc.",

year = "2019",

month = oct,

doi = "10.1016/j.kint.2019.05.015",

language = "English",

volume = "96",

pages = "850--861",

journal = "KIDNEY INT",

issn = "0085-2538",

publisher = "NATURE PUBLISHING GROUP",

number = "4",

}

RIS

TY - JOUR

T1 - From podocyte biology to novel cures for glomerular disease

AU - Torban, Elena

AU - Braun, Fabian

AU - Wanner, Nicola

AU - Takano, Tomoko

AU - Goodyer, Paul R

AU - Lennon, Rachel

AU - Ronco, Pierre

AU - Cybulsky, Andrey V

AU - Huber, Tobias B

PY - 2019/10

Y1 - 2019/10

N2 - The podocyte is a key component of the glomerular filtration barrier. Podocyte dysfunction is central to the underlying pathophysiology of many common glomerular diseases, including diabetic nephropathy, glomerulonephritis and genetic forms of nephrotic syndrome. Collectively, these conditions affect millions of people worldwide, and account for the majority of kidney diseases requiring dialysis and transplantation. The 12th International Podocyte Conference was held in Montreal, Canada from May 30 to June 2, 2018. The primary aim of this conference was to bring together nephrologists, clinician scientists, basic scientists and their trainees from all over the world to present their research and to establish networks with the common goal of developing new therapies for glomerular diseases based on the latest advances in podocyte biology. This review briefly highlights recent advances made in understanding podocyte structure and metabolism, experimental systems in which to study podocytes and glomerular disease, disease mediators, genetic and immune origins of glomerulopathies, and the development of novel therapeutic agents to protect podocyte and glomerular injury.

AB - The podocyte is a key component of the glomerular filtration barrier. Podocyte dysfunction is central to the underlying pathophysiology of many common glomerular diseases, including diabetic nephropathy, glomerulonephritis and genetic forms of nephrotic syndrome. Collectively, these conditions affect millions of people worldwide, and account for the majority of kidney diseases requiring dialysis and transplantation. The 12th International Podocyte Conference was held in Montreal, Canada from May 30 to June 2, 2018. The primary aim of this conference was to bring together nephrologists, clinician scientists, basic scientists and their trainees from all over the world to present their research and to establish networks with the common goal of developing new therapies for glomerular diseases based on the latest advances in podocyte biology. This review briefly highlights recent advances made in understanding podocyte structure and metabolism, experimental systems in which to study podocytes and glomerular disease, disease mediators, genetic and immune origins of glomerulopathies, and the development of novel therapeutic agents to protect podocyte and glomerular injury.

U2 - 10.1016/j.kint.2019.05.015

DO - 10.1016/j.kint.2019.05.015

M3 - SCORING: Review article

C2 - 31420194

VL - 96

SP - 850

EP - 861

JO - KIDNEY INT

JF - KIDNEY INT

SN - 0085-2538

IS - 4

ER -