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From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety.

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From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety. / Petrocchi, Alessia; Koch-Gromus, Uwe; Matassa, Victor G; Pacini, Barbara; Stillmock, Kara A; Summa, Vincenzo.

in: BIOORG MED CHEM LETT, Jahrgang 17, Nr. 2, 2, 2007, S. 350-353.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Petrocchi, A, Koch-Gromus, U, Matassa, VG, Pacini, B, Stillmock, KA & Summa, V 2007, 'From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety.', BIOORG MED CHEM LETT, Jg. 17, Nr. 2, 2, S. 350-353. <http://www.ncbi.nlm.nih.gov/pubmed/17107799?dopt=Citation>

APA

Petrocchi, A., Koch-Gromus, U., Matassa, V. G., Pacini, B., Stillmock, K. A., & Summa, V. (2007). From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety. BIOORG MED CHEM LETT, 17(2), 350-353. [2]. http://www.ncbi.nlm.nih.gov/pubmed/17107799?dopt=Citation

Vancouver

Petrocchi A, Koch-Gromus U, Matassa VG, Pacini B, Stillmock KA, Summa V. From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety. BIOORG MED CHEM LETT. 2007;17(2):350-353. 2.

Bibtex

@article{64605be2fed749ed878597d5d844d6c8,
title = "From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety.",
abstract = "4,5-Dihyroxypyrimidine carboxamides, which evolved from a related series of HCV NS5b polymerase inhibitors, have been optimized to provide selective HIV integrase strand transfer inhibitors. Extensive SAR around the benzylamide moiety led to the identification of the p-fluorobenzylamide as optimal in the enzymatic assay.",
author = "Alessia Petrocchi and Uwe Koch-Gromus and Matassa, {Victor G} and Barbara Pacini and Stillmock, {Kara A} and Vincenzo Summa",
year = "2007",
language = "Deutsch",
volume = "17",
pages = "350--353",
number = "2",

}

RIS

TY - JOUR

T1 - From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety.

AU - Petrocchi, Alessia

AU - Koch-Gromus, Uwe

AU - Matassa, Victor G

AU - Pacini, Barbara

AU - Stillmock, Kara A

AU - Summa, Vincenzo

PY - 2007

Y1 - 2007

N2 - 4,5-Dihyroxypyrimidine carboxamides, which evolved from a related series of HCV NS5b polymerase inhibitors, have been optimized to provide selective HIV integrase strand transfer inhibitors. Extensive SAR around the benzylamide moiety led to the identification of the p-fluorobenzylamide as optimal in the enzymatic assay.

AB - 4,5-Dihyroxypyrimidine carboxamides, which evolved from a related series of HCV NS5b polymerase inhibitors, have been optimized to provide selective HIV integrase strand transfer inhibitors. Extensive SAR around the benzylamide moiety led to the identification of the p-fluorobenzylamide as optimal in the enzymatic assay.

M3 - SCORING: Zeitschriftenaufsatz

VL - 17

SP - 350

EP - 353

IS - 2

M1 - 2

ER -