Frequency of vacA genotypes and cytotoxin activity in Helicobacter pylori associated with low-grade gastric mucosa-associated lymphoid tissue lymphoma

  • S Miehlke
  • A Meining
  • A Morgner
  • E Bayerdörffer
  • N Lehn
  • M Stolte
  • D Y Graham
  • M F Go

Abstract

The vacA genotypes s1,m1 and s1,m2 were detected in 44 and 30% of Helicobacter pylori isolates, respectively, from patients with gastric mucosa-associated lymphoid tissue lymphoma, compared to 26 and 56% of isolates, respectively, from individuals with gastritis. The vacA s1 genotype was significantly associated with, but not predictive of, the presence of vacuolating cytotoxin activity.

Bibliografische Daten

OriginalspracheEnglisch
ISSN0095-1137
StatusVeröffentlicht - 08.1998
Extern publiziertJa
PubMed 9666027