Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings

J. Remppis; A. Verheyden; A. L. Bustinduy; T. Heller; N. García-Tardón; G. P. Manouana; R. Obiang; A. A. Adegnika; M. P. Grobusch; M. Ramharter; E. Joekes; S. Bélard

doi:10.1093/trstmh/trz101

Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings

Standard

Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings. / Remppis, J.; Verheyden, A.; Bustinduy, A. L.; Heller, T.; García-Tardón, N.; Manouana, G. P.; Obiang, R.; Adegnika, A. A.; Grobusch, M. P.; Ramharter, M.; Joekes, E.; Bélard, S.

in: Transactions of the Royal Society of Tropical Medicine and Hygiene, Jahrgang 114, Nr. 1, 06.01.2020, S. 38-48.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Remppis, J, Verheyden, A, Bustinduy, AL, Heller, T, García-Tardón, N, Manouana, GP, Obiang, R, Adegnika, AA, Grobusch, MP, Ramharter, M, Joekes, E & Bélard, S 2020, 'Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings', Transactions of the Royal Society of Tropical Medicine and Hygiene, Jg. 114, Nr. 1, S. 38-48. https://doi.org/10.1093/trstmh/trz101

APA

Remppis, J., Verheyden, A., Bustinduy, A. L., Heller, T., García-Tardón, N., Manouana, G. P., Obiang, R., Adegnika, A. A., Grobusch, M. P., Ramharter, M., Joekes, E., & Bélard, S. (2020). Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings. Transactions of the Royal Society of Tropical Medicine and Hygiene, 114(1), 38-48. https://doi.org/10.1093/trstmh/trz101

Vancouver

Remppis J, Verheyden A, Bustinduy AL, Heller T, García-Tardón N, Manouana GP et al. Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2020 Jan 6;114(1):38-48. https://doi.org/10.1093/trstmh/trz101

Bibtex

@article{d8425a6d79a14f878062b0de3e94d3cb,

title = "Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings",

abstract = "Background: Urogenital schistosomiasis (UGS) causes inflammation and fibrosis of the urinary tract. In resource-limited settings, affordable tools for morbidity assessment in clinical care are needed. Point-of-care ultrasound has not yet been validated for UGS-related pathology. Methods: We developed a protocol for Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS), assessing pathology of the bladder wall, ureters and kidneys. Following standardized training, two clinicians performed FASUS on children and adults with hematuria in Lambar{\'e}n{\'e}, Gabon. Recorded ultrasound clips were remotely reviewed by two ultrasound experts as a diagnostic reference. Results: In 2015 and 2016, scans were performed in 118 patients. The image quality was sufficient in 90% of bladder views and more than 97% of kidney views. UGS-compatible pathology was detected in 51/118 (43%) by the operator and in 46/107 (43%) by the experts among baseline scans of sufficient quality. Inter-rater agreement between operators and experts was very good (κ > 0.8) for hydronephrosis and good (κ > 0.6) for bladder wall thickening. Conclusions: FASUS is a promising clinical, point-of-care tool for detecting UGS-related urinary tract morbidity in symptomatic patients. Based on larger validation studies, appropriate diagnostic and therapeutic algorithms for the use of FASUS should be established.",

keywords = "diagnostic imaging, Gabon, hydronephrosis, point-of-care testing, Schistosoma haematobium, tropical medicine, Humans, Morbidity, Pilot Projects, Animals, Point-of-Care Systems, Schistosomiasis haematobia/diagnostic imaging, Ultrasonography, Adult, Child",

author = "J. Remppis and A. Verheyden and Bustinduy, {A. L.} and T. Heller and N. Garc{\'i}a-Tard{\'o}n and Manouana, {G. P.} and R. Obiang and Adegnika, {A. A.} and Grobusch, {M. P.} and M. Ramharter and E. Joekes and S. B{\'e}lard",

note = "{\textcopyright} The Author(s) 2019. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",

year = "2020",

month = jan,

day = "6",

doi = "10.1093/trstmh/trz101",

language = "English",

volume = "114",

pages = "38--48",

journal = "T ROY SOC TROP MED H",

issn = "0035-9203",

publisher = "Elsevier",

number = "1",

}

RIS

TY - JOUR

T1 - Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings

AU - Remppis, J.

AU - Verheyden, A.

AU - Bustinduy, A. L.

AU - Heller, T.

AU - García-Tardón, N.

AU - Manouana, G. P.

AU - Obiang, R.

AU - Adegnika, A. A.

AU - Grobusch, M. P.

AU - Ramharter, M.

AU - Joekes, E.

AU - Bélard, S.

N1 - © The Author(s) 2019. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2020/1/6

Y1 - 2020/1/6

N2 - Background: Urogenital schistosomiasis (UGS) causes inflammation and fibrosis of the urinary tract. In resource-limited settings, affordable tools for morbidity assessment in clinical care are needed. Point-of-care ultrasound has not yet been validated for UGS-related pathology. Methods: We developed a protocol for Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS), assessing pathology of the bladder wall, ureters and kidneys. Following standardized training, two clinicians performed FASUS on children and adults with hematuria in Lambaréné, Gabon. Recorded ultrasound clips were remotely reviewed by two ultrasound experts as a diagnostic reference. Results: In 2015 and 2016, scans were performed in 118 patients. The image quality was sufficient in 90% of bladder views and more than 97% of kidney views. UGS-compatible pathology was detected in 51/118 (43%) by the operator and in 46/107 (43%) by the experts among baseline scans of sufficient quality. Inter-rater agreement between operators and experts was very good (κ > 0.8) for hydronephrosis and good (κ > 0.6) for bladder wall thickening. Conclusions: FASUS is a promising clinical, point-of-care tool for detecting UGS-related urinary tract morbidity in symptomatic patients. Based on larger validation studies, appropriate diagnostic and therapeutic algorithms for the use of FASUS should be established.

AB - Background: Urogenital schistosomiasis (UGS) causes inflammation and fibrosis of the urinary tract. In resource-limited settings, affordable tools for morbidity assessment in clinical care are needed. Point-of-care ultrasound has not yet been validated for UGS-related pathology. Methods: We developed a protocol for Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS), assessing pathology of the bladder wall, ureters and kidneys. Following standardized training, two clinicians performed FASUS on children and adults with hematuria in Lambaréné, Gabon. Recorded ultrasound clips were remotely reviewed by two ultrasound experts as a diagnostic reference. Results: In 2015 and 2016, scans were performed in 118 patients. The image quality was sufficient in 90% of bladder views and more than 97% of kidney views. UGS-compatible pathology was detected in 51/118 (43%) by the operator and in 46/107 (43%) by the experts among baseline scans of sufficient quality. Inter-rater agreement between operators and experts was very good (κ > 0.8) for hydronephrosis and good (κ > 0.6) for bladder wall thickening. Conclusions: FASUS is a promising clinical, point-of-care tool for detecting UGS-related urinary tract morbidity in symptomatic patients. Based on larger validation studies, appropriate diagnostic and therapeutic algorithms for the use of FASUS should be established.

KW - diagnostic imaging

KW - Gabon

KW - hydronephrosis

KW - point-of-care testing

KW - Schistosoma haematobium

KW - tropical medicine

KW - Humans

KW - Morbidity

KW - Pilot Projects

KW - Animals

KW - Point-of-Care Systems

KW - Schistosomiasis haematobia/diagnostic imaging

KW - Ultrasonography

KW - Adult

KW - Child

UR - http://www.scopus.com/inward/record.url?scp=85077948740&partnerID=8YFLogxK

U2 - 10.1093/trstmh/trz101

DO - 10.1093/trstmh/trz101

M3 - SCORING: Journal article

C2 - 31735956

AN - SCOPUS:85077948740

VL - 114

SP - 38

EP - 48

JO - T ROY SOC TROP MED H

JF - T ROY SOC TROP MED H

SN - 0035-9203

IS - 1

ER -