Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.

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Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease. / Leypoldt, Frank; Buchert, Ralph; Kleiter, Ingo; Marienhagen, Jörg; Gelderblom, Mathias; Magnus, Tim; Dalmau, Josep; Gerloff, Christian; Lewerenz, Jan.

in: J NEUROL NEUROSUR PS, Jahrgang 83, Nr. 7, 7, 01.07.2012, S. 681-686.

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@article{7bd5d8d13a994f28b47e126446a93805,
title = "Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.",
abstract = "Patients with encephalitis associated with antibodies against N-methyl-D-aspartate-receptor antibody (NMDAR-ab) encephalitis frequently show psychotic symptoms, amnesia, seizures and movement disorders. While brain MRI in NMDAR-ab encephalitis is often normal, abnormalities of cerebral glucose metabolism have been demonstrated by positron emission tomography (PET) with 18F-fluorodeoxyglucose(FDG) in a few usually isolated case reports. However, a common pattern of FDG-PET abnormalities has not been reported.",
keywords = "Adult, Humans, Male, Female, Young Adult, Retrospective Studies, Radiopharmaceuticals/diagnostic use, Positron-Emission Tomography/*methods, Glucose/metabolism, Anti-N-Methyl-D-Aspartate Receptor Encephalitis/*pathology, Brain/metabolism/*pathology, Fluorodeoxyglucose F18/diagnostic use, Frontal Lobe/pathology, Neuroimaging/methods, Temporal Lobe/metabolism/pathology, Adult, Humans, Male, Female, Young Adult, Retrospective Studies, Radiopharmaceuticals/diagnostic use, Positron-Emission Tomography/*methods, Glucose/metabolism, Anti-N-Methyl-D-Aspartate Receptor Encephalitis/*pathology, Brain/metabolism/*pathology, Fluorodeoxyglucose F18/diagnostic use, Frontal Lobe/pathology, Neuroimaging/methods, Temporal Lobe/metabolism/pathology",
author = "Frank Leypoldt and Ralph Buchert and Ingo Kleiter and J{\"o}rg Marienhagen and Mathias Gelderblom and Tim Magnus and Josep Dalmau and Christian Gerloff and Jan Lewerenz",
year = "2012",
month = jul,
day = "1",
doi = "10.1136/jnnp-2011-301969",
language = "English",
volume = "83",
pages = "681--686",
journal = "J NEUROL NEUROSUR PS",
issn = "0022-3050",
publisher = "BMJ PUBLISHING GROUP",
number = "7",

}

RIS

TY - JOUR

T1 - Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.

AU - Leypoldt, Frank

AU - Buchert, Ralph

AU - Kleiter, Ingo

AU - Marienhagen, Jörg

AU - Gelderblom, Mathias

AU - Magnus, Tim

AU - Dalmau, Josep

AU - Gerloff, Christian

AU - Lewerenz, Jan

PY - 2012/7/1

Y1 - 2012/7/1

N2 - Patients with encephalitis associated with antibodies against N-methyl-D-aspartate-receptor antibody (NMDAR-ab) encephalitis frequently show psychotic symptoms, amnesia, seizures and movement disorders. While brain MRI in NMDAR-ab encephalitis is often normal, abnormalities of cerebral glucose metabolism have been demonstrated by positron emission tomography (PET) with 18F-fluorodeoxyglucose(FDG) in a few usually isolated case reports. However, a common pattern of FDG-PET abnormalities has not been reported.

AB - Patients with encephalitis associated with antibodies against N-methyl-D-aspartate-receptor antibody (NMDAR-ab) encephalitis frequently show psychotic symptoms, amnesia, seizures and movement disorders. While brain MRI in NMDAR-ab encephalitis is often normal, abnormalities of cerebral glucose metabolism have been demonstrated by positron emission tomography (PET) with 18F-fluorodeoxyglucose(FDG) in a few usually isolated case reports. However, a common pattern of FDG-PET abnormalities has not been reported.

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Young Adult

KW - Retrospective Studies

KW - Radiopharmaceuticals/diagnostic use

KW - Positron-Emission Tomography/methods

KW - Glucose/metabolism

KW - Anti-N-Methyl-D-Aspartate Receptor Encephalitis/pathology

KW - Brain/metabolism/pathology

KW - Fluorodeoxyglucose F18/diagnostic use

KW - Frontal Lobe/pathology

KW - Neuroimaging/methods

KW - Temporal Lobe/metabolism/pathology

KW - Adult

KW - Humans

KW - Male

KW - Female

KW - Young Adult

KW - Retrospective Studies

KW - Radiopharmaceuticals/diagnostic use

KW - Positron-Emission Tomography/methods

KW - Glucose/metabolism

KW - Anti-N-Methyl-D-Aspartate Receptor Encephalitis/pathology

KW - Brain/metabolism/pathology

KW - Fluorodeoxyglucose F18/diagnostic use

KW - Frontal Lobe/pathology

KW - Neuroimaging/methods

KW - Temporal Lobe/metabolism/pathology

U2 - 10.1136/jnnp-2011-301969

DO - 10.1136/jnnp-2011-301969

M3 - SCORING: Journal article

C2 - 22566598

VL - 83

SP - 681

EP - 686

JO - J NEUROL NEUROSUR PS

JF - J NEUROL NEUROSUR PS

SN - 0022-3050

IS - 7

M1 - 7

ER -