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Flumazenil attenuates the pituitary response to CRH in healthy males.

Standard

Flumazenil attenuates the pituitary response to CRH in healthy males. / Ströhle, A; Wiedemann, Klaus.

in: EUR NEUROPSYCHOPHARM, Jahrgang 6, Nr. 4, 4, 1996, S. 323-325.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Ströhle, A & Wiedemann, K 1996, 'Flumazenil attenuates the pituitary response to CRH in healthy males.', EUR NEUROPSYCHOPHARM, Jg. 6, Nr. 4, 4, S. 323-325. <http://www.ncbi.nlm.nih.gov/pubmed/8985717?dopt=Citation>

APA

Ströhle, A., & Wiedemann, K. (1996). Flumazenil attenuates the pituitary response to CRH in healthy males. EUR NEUROPSYCHOPHARM, 6(4), 323-325. [4]. http://www.ncbi.nlm.nih.gov/pubmed/8985717?dopt=Citation

Vancouver

Ströhle A, Wiedemann K. Flumazenil attenuates the pituitary response to CRH in healthy males. EUR NEUROPSYCHOPHARM. 1996;6(4):323-325. 4.

Bibtex

@article{181a07d330414020a4d4e5980f871eaf,
title = "Flumazenil attenuates the pituitary response to CRH in healthy males.",
abstract = "Differential effects of flumazenil (an antagonist) and midazolam (an antagonist at the benzodiazepine receptor) were studied in 8 healthy males. Adrenocorticotropic hormone (ACTH) and cortisol responses to a corticotropin-releasing hormone (CRH) challenge were measured. ACTH response was significantly lower after flumazenil administration than after saline or midazolam. No significant treatment effect was found for the CRH-induced cortisol secretion. Our results agree with previous reports that point to an agonistic effect of flumazenil on pituitary-adrenocortical system activity and, moreover, may further support the anxiolytic activity of flumazenil in stimulated stress.",
author = "A Str{\"o}hle and Klaus Wiedemann",
year = "1996",
language = "Deutsch",
volume = "6",
pages = "323--325",
journal = "EUR NEUROPSYCHOPHARM",
issn = "0924-977X",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Flumazenil attenuates the pituitary response to CRH in healthy males.

AU - Ströhle, A

AU - Wiedemann, Klaus

PY - 1996

Y1 - 1996

N2 - Differential effects of flumazenil (an antagonist) and midazolam (an antagonist at the benzodiazepine receptor) were studied in 8 healthy males. Adrenocorticotropic hormone (ACTH) and cortisol responses to a corticotropin-releasing hormone (CRH) challenge were measured. ACTH response was significantly lower after flumazenil administration than after saline or midazolam. No significant treatment effect was found for the CRH-induced cortisol secretion. Our results agree with previous reports that point to an agonistic effect of flumazenil on pituitary-adrenocortical system activity and, moreover, may further support the anxiolytic activity of flumazenil in stimulated stress.

AB - Differential effects of flumazenil (an antagonist) and midazolam (an antagonist at the benzodiazepine receptor) were studied in 8 healthy males. Adrenocorticotropic hormone (ACTH) and cortisol responses to a corticotropin-releasing hormone (CRH) challenge were measured. ACTH response was significantly lower after flumazenil administration than after saline or midazolam. No significant treatment effect was found for the CRH-induced cortisol secretion. Our results agree with previous reports that point to an agonistic effect of flumazenil on pituitary-adrenocortical system activity and, moreover, may further support the anxiolytic activity of flumazenil in stimulated stress.

M3 - SCORING: Zeitschriftenaufsatz

VL - 6

SP - 323

EP - 325

JO - EUR NEUROPSYCHOPHARM

JF - EUR NEUROPSYCHOPHARM

SN - 0924-977X

IS - 4

M1 - 4

ER -