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Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success

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Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success. / Schreiber, Doreen; Rostock, Thomas; Fröhlich, Max; Sultan, Arian; Servatius, Helge; Hoffmann, Boris A; Lüker, Jakob; Berner, Imke; Schäffer, Benjamin; Wegscheider, Karl; Lezius, Susanne; Willems, Stephan; Steven, Daniel.

in: CIRC-ARRHYTHMIA ELEC, Jahrgang 8, Nr. 2, 01.04.2015, S. 308-17.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schreiber, D, Rostock, T, Fröhlich, M, Sultan, A, Servatius, H, Hoffmann, BA, Lüker, J, Berner, I, Schäffer, B, Wegscheider, K, Lezius, S, Willems, S & Steven, D 2015, 'Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success', CIRC-ARRHYTHMIA ELEC, Jg. 8, Nr. 2, S. 308-17. https://doi.org/10.1161/CIRCEP.114.001672

APA

Schreiber, D., Rostock, T., Fröhlich, M., Sultan, A., Servatius, H., Hoffmann, B. A., Lüker, J., Berner, I., Schäffer, B., Wegscheider, K., Lezius, S., Willems, S., & Steven, D. (2015). Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success. CIRC-ARRHYTHMIA ELEC, 8(2), 308-17. https://doi.org/10.1161/CIRCEP.114.001672

Vancouver

Schreiber D, Rostock T, Fröhlich M, Sultan A, Servatius H, Hoffmann BA et al. Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success. CIRC-ARRHYTHMIA ELEC. 2015 Apr 1;8(2):308-17. https://doi.org/10.1161/CIRCEP.114.001672

Bibtex

@article{39b6cc8f3d2c477695205018a954a75c,
title = "Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success",
abstract = "BACKGROUND: In the meantime, catheter ablation is widely used for the treatment of persistent atrial fibrillation (AF). There is a paucity of data about long-term outcomes. This study evaluates (1) 5-year single and multiple procedure success and (2) prognostic factors for arrhythmia recurrences after catheter ablation of persistent AF using the stepwise approach aiming at AF termination.METHODS AND RESULTS: A total of 549 patients with persistent AF underwent de novo catheter ablation using the stepwise approach (2007-2009). A total of 493 patients were included (Holter ECGs ≥every 6 months). Mean follow-up was 59±16 months with 2.1±1.1 procedures per patient. Single and multiple procedure success rates were 20.1% and 55.9%, respectively (80% off antiarrhythmic drug). Antiarrhythmic drug-free multiple procedure success was 46%. Long-term recurrences (n=171) were paroxysmal AF in 48 patients (28%) and persistent AF/atrial tachycardia in 123 patients (72%). Multivariable recurrent event analysis revealed the following factors favoring arrhythmia recurrence: failure to terminate AF during index procedure (hazard ratio [HR], 1.279; 95% confidence interval [CI], 1.093-1.497; P=0.002), number of procedures (HR, 1.154; 95% CI, 1.051-1.267; P=0.003), female sex (HR, 1.263; 95% CI, 1.027-1.553; P=0.027), and the presence of structural heart disease (HR, 1.236; 95% CI, 1.003-1.524; P=0.047). AF termination was correlated with a higher rate of consecutive procedures because of atrial tachycardia recurrences (P=0.003; HR, 1.71; 95% CI, 1.20-2.43).CONCLUSIONS: Catheter ablation of persistent AF using the stepwise approach provides limited long-term freedom of arrhythmias often requiring multiple procedures. AF termination, the number of procedures, sex, and the presence of structural heart disease correlate with outcome success. AF termination is associated with consecutive atrial tachycardia procedures.",
author = "Doreen Schreiber and Thomas Rostock and Max Fr{\"o}hlich and Arian Sultan and Helge Servatius and Hoffmann, {Boris A} and Jakob L{\"u}ker and Imke Berner and Benjamin Sch{\"a}ffer and Karl Wegscheider and Susanne Lezius and Stephan Willems and Daniel Steven",
note = "{\textcopyright} 2015 American Heart Association, Inc.",
year = "2015",
month = apr,
day = "1",
doi = "10.1161/CIRCEP.114.001672",
language = "English",
volume = "8",
pages = "308--17",
journal = "CIRC-ARRHYTHMIA ELEC",
issn = "1941-3149",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

RIS

TY - JOUR

T1 - Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success

AU - Schreiber, Doreen

AU - Rostock, Thomas

AU - Fröhlich, Max

AU - Sultan, Arian

AU - Servatius, Helge

AU - Hoffmann, Boris A

AU - Lüker, Jakob

AU - Berner, Imke

AU - Schäffer, Benjamin

AU - Wegscheider, Karl

AU - Lezius, Susanne

AU - Willems, Stephan

AU - Steven, Daniel

N1 - © 2015 American Heart Association, Inc.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - BACKGROUND: In the meantime, catheter ablation is widely used for the treatment of persistent atrial fibrillation (AF). There is a paucity of data about long-term outcomes. This study evaluates (1) 5-year single and multiple procedure success and (2) prognostic factors for arrhythmia recurrences after catheter ablation of persistent AF using the stepwise approach aiming at AF termination.METHODS AND RESULTS: A total of 549 patients with persistent AF underwent de novo catheter ablation using the stepwise approach (2007-2009). A total of 493 patients were included (Holter ECGs ≥every 6 months). Mean follow-up was 59±16 months with 2.1±1.1 procedures per patient. Single and multiple procedure success rates were 20.1% and 55.9%, respectively (80% off antiarrhythmic drug). Antiarrhythmic drug-free multiple procedure success was 46%. Long-term recurrences (n=171) were paroxysmal AF in 48 patients (28%) and persistent AF/atrial tachycardia in 123 patients (72%). Multivariable recurrent event analysis revealed the following factors favoring arrhythmia recurrence: failure to terminate AF during index procedure (hazard ratio [HR], 1.279; 95% confidence interval [CI], 1.093-1.497; P=0.002), number of procedures (HR, 1.154; 95% CI, 1.051-1.267; P=0.003), female sex (HR, 1.263; 95% CI, 1.027-1.553; P=0.027), and the presence of structural heart disease (HR, 1.236; 95% CI, 1.003-1.524; P=0.047). AF termination was correlated with a higher rate of consecutive procedures because of atrial tachycardia recurrences (P=0.003; HR, 1.71; 95% CI, 1.20-2.43).CONCLUSIONS: Catheter ablation of persistent AF using the stepwise approach provides limited long-term freedom of arrhythmias often requiring multiple procedures. AF termination, the number of procedures, sex, and the presence of structural heart disease correlate with outcome success. AF termination is associated with consecutive atrial tachycardia procedures.

AB - BACKGROUND: In the meantime, catheter ablation is widely used for the treatment of persistent atrial fibrillation (AF). There is a paucity of data about long-term outcomes. This study evaluates (1) 5-year single and multiple procedure success and (2) prognostic factors for arrhythmia recurrences after catheter ablation of persistent AF using the stepwise approach aiming at AF termination.METHODS AND RESULTS: A total of 549 patients with persistent AF underwent de novo catheter ablation using the stepwise approach (2007-2009). A total of 493 patients were included (Holter ECGs ≥every 6 months). Mean follow-up was 59±16 months with 2.1±1.1 procedures per patient. Single and multiple procedure success rates were 20.1% and 55.9%, respectively (80% off antiarrhythmic drug). Antiarrhythmic drug-free multiple procedure success was 46%. Long-term recurrences (n=171) were paroxysmal AF in 48 patients (28%) and persistent AF/atrial tachycardia in 123 patients (72%). Multivariable recurrent event analysis revealed the following factors favoring arrhythmia recurrence: failure to terminate AF during index procedure (hazard ratio [HR], 1.279; 95% confidence interval [CI], 1.093-1.497; P=0.002), number of procedures (HR, 1.154; 95% CI, 1.051-1.267; P=0.003), female sex (HR, 1.263; 95% CI, 1.027-1.553; P=0.027), and the presence of structural heart disease (HR, 1.236; 95% CI, 1.003-1.524; P=0.047). AF termination was correlated with a higher rate of consecutive procedures because of atrial tachycardia recurrences (P=0.003; HR, 1.71; 95% CI, 1.20-2.43).CONCLUSIONS: Catheter ablation of persistent AF using the stepwise approach provides limited long-term freedom of arrhythmias often requiring multiple procedures. AF termination, the number of procedures, sex, and the presence of structural heart disease correlate with outcome success. AF termination is associated with consecutive atrial tachycardia procedures.

U2 - 10.1161/CIRCEP.114.001672

DO - 10.1161/CIRCEP.114.001672

M3 - SCORING: Journal article

C2 - 25744570

VL - 8

SP - 308

EP - 317

JO - CIRC-ARRHYTHMIA ELEC

JF - CIRC-ARRHYTHMIA ELEC

SN - 1941-3149

IS - 2

ER -