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FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria

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FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria. / Lötsch, Felix; Waneck, Fredrik; Groger, Mirjam; Auer, Herbert; Kaczirek, Klaus; Rausch, Ivo; Wadsak, Wolfgang; Hacker, Marcus; Lagler, Heimo; Ramharter, Michael; Karanikas, Georgios.

in: TROP MED INT HEALTH, Jahrgang 24, Nr. 6, 06.2019, S. 663-670.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lötsch, F, Waneck, F, Groger, M, Auer, H, Kaczirek, K, Rausch, I, Wadsak, W, Hacker, M, Lagler, H, Ramharter, M & Karanikas, G 2019, 'FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria', TROP MED INT HEALTH, Jg. 24, Nr. 6, S. 663-670. https://doi.org/10.1111/tmi.13228

APA

Lötsch, F., Waneck, F., Groger, M., Auer, H., Kaczirek, K., Rausch, I., Wadsak, W., Hacker, M., Lagler, H., Ramharter, M., & Karanikas, G. (2019). FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria. TROP MED INT HEALTH, 24(6), 663-670. https://doi.org/10.1111/tmi.13228

Vancouver

Lötsch F, Waneck F, Groger M, Auer H, Kaczirek K, Rausch I et al. FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria. TROP MED INT HEALTH. 2019 Jun;24(6):663-670. https://doi.org/10.1111/tmi.13228

Bibtex

@article{2775f3a864a740a395cf09aef86101b0,
title = "FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria",
abstract = "BACKGROUND: [18 F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (FDG-PET/CT) imaging provides important information about the size and metabolic activity of lesions caused by Echinococcus multilocularis and is therefore recommended for the initial assessment and follow-up of human alveolar echinococcosis (AE). The introduction of positron emission tomography/magnetic resonance imaging (PET/MRI) into clinical practice in affluent health care systems provides an alternative dual imaging modality, which has not yet been evaluated for AE.OBJECTIVE: Here, we describe the initial clinical experience with comparative PET/CT and PET/MR imaging in four human AE patients at an Austrian reference centre.RESULTS: PET/MR imaging showed comparable diagnostic capacity for liver lesions attributable to E. multilocularis infection, with a discrepancy only in the assessment of calcifications in one patient. Effective doses of radiation were 30.4-31 mSV for PET/CT, which were reduced in PET/MRI to the exposure of 18 F-FDG only (4.9-5.5 mSv).CONCLUSIONS: PET/MRI provides comparable diagnostic information for AE management. The reduction in radiation exposure compared to PET/CT may be of particular importance for children and young patients not amenable for curative surgery requiring repeated long-term follow-up with dual imaging modalities. Further studies are warranted to prospectively evaluate the potential of PET/MRI in the management of AE.",
keywords = "Aged, Animals, Austria, Echinococcosis/diagnostic imaging, Female, Fluorodeoxyglucose F18, Humans, Liver/diagnostic imaging, Magnetic Resonance Imaging, Male, Middle Aged, Positron Emission Tomography Computed Tomography",
author = "Felix L{\"o}tsch and Fredrik Waneck and Mirjam Groger and Herbert Auer and Klaus Kaczirek and Ivo Rausch and Wolfgang Wadsak and Marcus Hacker and Heimo Lagler and Michael Ramharter and Georgios Karanikas",
note = "{\textcopyright} 2019 John Wiley & Sons Ltd.",
year = "2019",
month = jun,
doi = "10.1111/tmi.13228",
language = "English",
volume = "24",
pages = "663--670",
journal = "TROP MED INT HEALTH",
issn = "1360-2276",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria

AU - Lötsch, Felix

AU - Waneck, Fredrik

AU - Groger, Mirjam

AU - Auer, Herbert

AU - Kaczirek, Klaus

AU - Rausch, Ivo

AU - Wadsak, Wolfgang

AU - Hacker, Marcus

AU - Lagler, Heimo

AU - Ramharter, Michael

AU - Karanikas, Georgios

N1 - © 2019 John Wiley & Sons Ltd.

PY - 2019/6

Y1 - 2019/6

N2 - BACKGROUND: [18 F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (FDG-PET/CT) imaging provides important information about the size and metabolic activity of lesions caused by Echinococcus multilocularis and is therefore recommended for the initial assessment and follow-up of human alveolar echinococcosis (AE). The introduction of positron emission tomography/magnetic resonance imaging (PET/MRI) into clinical practice in affluent health care systems provides an alternative dual imaging modality, which has not yet been evaluated for AE.OBJECTIVE: Here, we describe the initial clinical experience with comparative PET/CT and PET/MR imaging in four human AE patients at an Austrian reference centre.RESULTS: PET/MR imaging showed comparable diagnostic capacity for liver lesions attributable to E. multilocularis infection, with a discrepancy only in the assessment of calcifications in one patient. Effective doses of radiation were 30.4-31 mSV for PET/CT, which were reduced in PET/MRI to the exposure of 18 F-FDG only (4.9-5.5 mSv).CONCLUSIONS: PET/MRI provides comparable diagnostic information for AE management. The reduction in radiation exposure compared to PET/CT may be of particular importance for children and young patients not amenable for curative surgery requiring repeated long-term follow-up with dual imaging modalities. Further studies are warranted to prospectively evaluate the potential of PET/MRI in the management of AE.

AB - BACKGROUND: [18 F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (FDG-PET/CT) imaging provides important information about the size and metabolic activity of lesions caused by Echinococcus multilocularis and is therefore recommended for the initial assessment and follow-up of human alveolar echinococcosis (AE). The introduction of positron emission tomography/magnetic resonance imaging (PET/MRI) into clinical practice in affluent health care systems provides an alternative dual imaging modality, which has not yet been evaluated for AE.OBJECTIVE: Here, we describe the initial clinical experience with comparative PET/CT and PET/MR imaging in four human AE patients at an Austrian reference centre.RESULTS: PET/MR imaging showed comparable diagnostic capacity for liver lesions attributable to E. multilocularis infection, with a discrepancy only in the assessment of calcifications in one patient. Effective doses of radiation were 30.4-31 mSV for PET/CT, which were reduced in PET/MRI to the exposure of 18 F-FDG only (4.9-5.5 mSv).CONCLUSIONS: PET/MRI provides comparable diagnostic information for AE management. The reduction in radiation exposure compared to PET/CT may be of particular importance for children and young patients not amenable for curative surgery requiring repeated long-term follow-up with dual imaging modalities. Further studies are warranted to prospectively evaluate the potential of PET/MRI in the management of AE.

KW - Aged

KW - Animals

KW - Austria

KW - Echinococcosis/diagnostic imaging

KW - Female

KW - Fluorodeoxyglucose F18

KW - Humans

KW - Liver/diagnostic imaging

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Positron Emission Tomography Computed Tomography

U2 - 10.1111/tmi.13228

DO - 10.1111/tmi.13228

M3 - SCORING: Journal article

C2 - 30851233

VL - 24

SP - 663

EP - 670

JO - TROP MED INT HEALTH

JF - TROP MED INT HEALTH

SN - 1360-2276

IS - 6

ER -