Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma
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Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma : a prospective study using automatic, computer-based speech analysis. / Stelzle, Florian; Knipfer, Christian; Schuster, Maria; Bocklet, Tobias; Nöth, Elmar; Adler, Werner; Schempf, Luisa; Vieler, Peter; Riemann, Max; Neukam, Friedrich Wilhelm; Nkenke, Emeka.
in: INT J ORAL MAX SURG, Jahrgang 42, Nr. 11, 11.2013, S. 1377-84.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma
T2 - a prospective study using automatic, computer-based speech analysis
AU - Stelzle, Florian
AU - Knipfer, Christian
AU - Schuster, Maria
AU - Bocklet, Tobias
AU - Nöth, Elmar
AU - Adler, Werner
AU - Schempf, Luisa
AU - Vieler, Peter
AU - Riemann, Max
AU - Neukam, Friedrich Wilhelm
AU - Nkenke, Emeka
N1 - Copyright © 2013 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
PY - 2013/11
Y1 - 2013/11
N2 - Oral squamous cell carcinoma (OSCC) and its treatment impair speech intelligibility by alteration of the vocal tract. The aim of this study was to identify the factors of oral cancer treatment that influence speech intelligibility by means of an automatic, standardized speech-recognition system. The study group comprised 71 patients (mean age 59.89, range 35-82 years) with OSCC ranging from stage T1 to T4 (TNM staging). Tumours were located on the tongue (n=23), lower alveolar crest (n=27), and floor of the mouth (n=21). Reconstruction was conducted through local tissue plasty or microvascular transplants. Adjuvant radiotherapy was performed in 49 patients. Speech intelligibility was evaluated before, and at 3, 6, and 12 months after tumour resection, and compared to that of a healthy control group (n=40). Postoperatively, significant influences on speech intelligibility were tumour localization (P=0.010) and resection volume (P=0.019). Additionally, adjuvant radiotherapy (P=0.049) influenced intelligibility at 3 months after surgery. At 6 months after surgery, influences were resection volume (P=0.028) and adjuvant radiotherapy (P=0.034). The influence of tumour localization (P=0.001) and adjuvant radiotherapy (P=0.022) persisted after 12 months. Tumour localization, resection volume, and radiotherapy are crucial factors for speech intelligibility. Radiotherapy significantly impaired word recognition rate (WR) values with a progression of the impairment for up to 12 months after surgery.
AB - Oral squamous cell carcinoma (OSCC) and its treatment impair speech intelligibility by alteration of the vocal tract. The aim of this study was to identify the factors of oral cancer treatment that influence speech intelligibility by means of an automatic, standardized speech-recognition system. The study group comprised 71 patients (mean age 59.89, range 35-82 years) with OSCC ranging from stage T1 to T4 (TNM staging). Tumours were located on the tongue (n=23), lower alveolar crest (n=27), and floor of the mouth (n=21). Reconstruction was conducted through local tissue plasty or microvascular transplants. Adjuvant radiotherapy was performed in 49 patients. Speech intelligibility was evaluated before, and at 3, 6, and 12 months after tumour resection, and compared to that of a healthy control group (n=40). Postoperatively, significant influences on speech intelligibility were tumour localization (P=0.010) and resection volume (P=0.019). Additionally, adjuvant radiotherapy (P=0.049) influenced intelligibility at 3 months after surgery. At 6 months after surgery, influences were resection volume (P=0.028) and adjuvant radiotherapy (P=0.034). The influence of tumour localization (P=0.001) and adjuvant radiotherapy (P=0.022) persisted after 12 months. Tumour localization, resection volume, and radiotherapy are crucial factors for speech intelligibility. Radiotherapy significantly impaired word recognition rate (WR) values with a progression of the impairment for up to 12 months after surgery.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Carcinoma, Squamous Cell
KW - Case-Control Studies
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Mouth Neoplasms
KW - Neoplasm Staging
KW - Prospective Studies
KW - Radiotherapy, Adjuvant
KW - Reconstructive Surgical Procedures
KW - Regression Analysis
KW - Speech Disorders
KW - Speech Intelligibility
KW - Speech Recognition Software
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1016/j.ijom.2013.05.021
DO - 10.1016/j.ijom.2013.05.021
M3 - SCORING: Journal article
C2 - 23845298
VL - 42
SP - 1377
EP - 1384
JO - INT J ORAL MAX SURG
JF - INT J ORAL MAX SURG
SN - 0901-5027
IS - 11
ER -
