Extracellular NAD(+): a danger signal hindering regulatory T cells.

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Extracellular NAD(+): a danger signal hindering regulatory T cells. / Adriouch, Sahil; Haag, Friedrich; Boyer, Olivier; Seman, Michel; Koch Nolte, Friedrich.

in: MICROBES INFECT, Jahrgang 14, Nr. 14, 14, 01.11.2012, S. 1284-1292.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{50b47088d67b41be90a18f30ded57a1e,
title = "Extracellular NAD(+): a danger signal hindering regulatory T cells.",
abstract = "Endogenous danger signals released during cell damage contribute to alert the immune system. Typically, their release results in the activation and maturation of innate immune cells, and the production of pro-inflammatory cytokines. In addition, extracellular NAD(+) stimulates immune responses by hindering regulatory T cells (Tregs), and could, therefore, represent the prototype of a new category of danger signals.",
keywords = "Animals, Humans, T-Lymphocytes, Regulatory/*immunology, Cell Death/immunology, Cell Communication/*immunology, Extracellular Space/immunology, NAD/*immunology, Animals, Humans, T-Lymphocytes, Regulatory/*immunology, Cell Death/immunology, Cell Communication/*immunology, Extracellular Space/immunology, NAD/*immunology",
author = "Sahil Adriouch and Friedrich Haag and Olivier Boyer and Michel Seman and {Koch Nolte}, Friedrich",
note = "Copyright {\textcopyright} 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.",
year = "2012",
month = nov,
day = "1",
doi = "10.1016/j.micinf.2012.05.011",
language = "English",
volume = "14",
pages = "1284--1292",
journal = "MICROBES INFECT",
issn = "1286-4579",
publisher = "Elsevier Masson SAS",
number = "14",

}

RIS

TY - JOUR

T1 - Extracellular NAD(+): a danger signal hindering regulatory T cells.

AU - Adriouch, Sahil

AU - Haag, Friedrich

AU - Boyer, Olivier

AU - Seman, Michel

AU - Koch Nolte, Friedrich

N1 - Copyright © 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

PY - 2012/11/1

Y1 - 2012/11/1

N2 - Endogenous danger signals released during cell damage contribute to alert the immune system. Typically, their release results in the activation and maturation of innate immune cells, and the production of pro-inflammatory cytokines. In addition, extracellular NAD(+) stimulates immune responses by hindering regulatory T cells (Tregs), and could, therefore, represent the prototype of a new category of danger signals.

AB - Endogenous danger signals released during cell damage contribute to alert the immune system. Typically, their release results in the activation and maturation of innate immune cells, and the production of pro-inflammatory cytokines. In addition, extracellular NAD(+) stimulates immune responses by hindering regulatory T cells (Tregs), and could, therefore, represent the prototype of a new category of danger signals.

KW - Animals

KW - Humans

KW - T-Lymphocytes, Regulatory/immunology

KW - Cell Death/immunology

KW - Cell Communication/immunology

KW - Extracellular Space/immunology

KW - NAD/immunology

KW - Animals

KW - Humans

KW - T-Lymphocytes, Regulatory/immunology

KW - Cell Death/immunology

KW - Cell Communication/immunology

KW - Extracellular Space/immunology

KW - NAD/immunology

U2 - 10.1016/j.micinf.2012.05.011

DO - 10.1016/j.micinf.2012.05.011

M3 - SCORING: Journal article

C2 - 22634347

VL - 14

SP - 1284

EP - 1292

JO - MICROBES INFECT

JF - MICROBES INFECT

SN - 1286-4579

IS - 14

M1 - 14

ER -