PortalPublikationenExpression of neuron-specific enolase in irradiated salivary...

Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study.

Standard

Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study. / Friedrich, Reinhard; Davidoff, Michail; Bartel-Friedrich, Sylva.

in: ANTICANCER RES, Jahrgang 30, Nr. 5, 5, 01.05.2010, S. 1569-1571.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Friedrich, R, Davidoff, M & Bartel-Friedrich, S 2010, 'Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study.', ANTICANCER RES, Jg. 30, Nr. 5, 5, S. 1569-1571. <http://www.ncbi.nlm.nih.gov/pubmed/20592343?dopt=Citation>

APA

Friedrich, R., Davidoff, M., & Bartel-Friedrich, S. (2010). Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study. ANTICANCER RES, 30(5), 1569-1571. [5]. http://www.ncbi.nlm.nih.gov/pubmed/20592343?dopt=Citation

Vancouver

Friedrich R, Davidoff M, Bartel-Friedrich S. Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study. ANTICANCER RES. 2010 Mai 1;30(5):1569-1571. 5.

Bibtex

@article{68e21ec62d7644d88e4ad38da584e828,
title = "Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study.",
abstract = "External irradiation of advanced head and neck cancer often includes the major salivary glands, despite them not being affected by the disease. The aim of this study was to determine neuron-specific enolase (NSE) as a marker of inflammation in irradiated and non-irradiated salivary glands of the rat. This study shows that NSE expression in irradiated salivary glands is dependent on the topography of the organ related to the irradiation source. NSE immunostaining was increased in irradiated rats, both in glands directly exposed to the irradiation source and in shielded glands, and compared to glands of non-irradiated animals. Staining of NSE in salivary glands appears to indicate the inflammatory response of the organ to X-ray exposure. The increased immunoreactivity for NSE in shielded glands might be useful as a marker of irradiation in salivary glands, even for scattered radiation effects in major salivary glands.",
keywords = "Animals, Cell Nucleus, Cytoplasm, Female, Gene Expression Regulation, Enzymologic, Phosphopyruvate Hydratase, Pilot Projects, Rats, Rats, Sprague-Dawley, Rats, Wistar, Salivary Glands, Submandibular Gland, X-Rays",
author = "Reinhard Friedrich and Michail Davidoff and Sylva Bartel-Friedrich",
year = "2010",
month = may,
day = "1",
language = "English",
volume = "30",
pages = "1569--1571",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "5",

}

RIS

TY - JOUR

T1 - Expression of neuron-specific enolase in irradiated salivary glands of the rat: a pilot study.

AU - Friedrich, Reinhard

AU - Davidoff, Michail

AU - Bartel-Friedrich, Sylva

PY - 2010/5/1

Y1 - 2010/5/1

N2 - External irradiation of advanced head and neck cancer often includes the major salivary glands, despite them not being affected by the disease. The aim of this study was to determine neuron-specific enolase (NSE) as a marker of inflammation in irradiated and non-irradiated salivary glands of the rat. This study shows that NSE expression in irradiated salivary glands is dependent on the topography of the organ related to the irradiation source. NSE immunostaining was increased in irradiated rats, both in glands directly exposed to the irradiation source and in shielded glands, and compared to glands of non-irradiated animals. Staining of NSE in salivary glands appears to indicate the inflammatory response of the organ to X-ray exposure. The increased immunoreactivity for NSE in shielded glands might be useful as a marker of irradiation in salivary glands, even for scattered radiation effects in major salivary glands.

AB - External irradiation of advanced head and neck cancer often includes the major salivary glands, despite them not being affected by the disease. The aim of this study was to determine neuron-specific enolase (NSE) as a marker of inflammation in irradiated and non-irradiated salivary glands of the rat. This study shows that NSE expression in irradiated salivary glands is dependent on the topography of the organ related to the irradiation source. NSE immunostaining was increased in irradiated rats, both in glands directly exposed to the irradiation source and in shielded glands, and compared to glands of non-irradiated animals. Staining of NSE in salivary glands appears to indicate the inflammatory response of the organ to X-ray exposure. The increased immunoreactivity for NSE in shielded glands might be useful as a marker of irradiation in salivary glands, even for scattered radiation effects in major salivary glands.

KW - Animals

KW - Cell Nucleus

KW - Cytoplasm

KW - Female

KW - Gene Expression Regulation, Enzymologic

KW - Phosphopyruvate Hydratase

KW - Pilot Projects

KW - Rats

KW - Rats, Sprague-Dawley

KW - Rats, Wistar

KW - Salivary Glands

KW - Submandibular Gland

KW - X-Rays

M3 - SCORING: Journal article

C2 - 20592343

VL - 30

SP - 1569

EP - 1571

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 5

M1 - 5

ER -