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Exosomes in Immune Regulation

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Exosomes in Immune Regulation. / Schwarzenbach, Heidi; Gahan, Peter B.

in: NON-CODING RNA, Jahrgang 7, Nr. 1, 4, 08.01.2021.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Schwarzenbach, H & Gahan, PB 2021, 'Exosomes in Immune Regulation', NON-CODING RNA, Jg. 7, Nr. 1, 4. https://doi.org/10.3390/ncrna7010004

APA

Schwarzenbach, H., & Gahan, P. B. (2021). Exosomes in Immune Regulation. NON-CODING RNA, 7(1), [4]. https://doi.org/10.3390/ncrna7010004

Vancouver

Schwarzenbach H, Gahan PB. Exosomes in Immune Regulation. NON-CODING RNA. 2021 Jan 8;7(1). 4. https://doi.org/10.3390/ncrna7010004

Bibtex

@article{37e592e129d64c9080590fa52aa12f6d,
title = "Exosomes in Immune Regulation",
abstract = "Exosomes, small extracellular vesicles mediate intercellular communication by transferring their cargo including DNA, RNA, proteins and lipids from cell to cell. Notably, in the immune system, they have protective functions. However in cancer, exosomes acquire new, immunosuppressive properties that cause the dysregulation of immune cells and immune escape of tumor cells supporting cancer progression and metastasis. Therefore, current investigations focus on the regulation of exosome levels for immunotherapeutic interventions. In this review, we discuss the role of exosomes in immunomodulation of lymphoid and myeloid cells, and their use as immune stimulatory agents to elicit specific cytotoxic responses against the tumor.",
author = "Heidi Schwarzenbach and Gahan, {Peter B}",
year = "2021",
month = jan,
day = "8",
doi = "10.3390/ncrna7010004",
language = "English",
volume = "7",
journal = "NON-CODING RNA",
issn = "2311-553X",
publisher = "MDPI AG",
number = "1",

}

RIS

TY - JOUR

T1 - Exosomes in Immune Regulation

AU - Schwarzenbach, Heidi

AU - Gahan, Peter B

PY - 2021/1/8

Y1 - 2021/1/8

N2 - Exosomes, small extracellular vesicles mediate intercellular communication by transferring their cargo including DNA, RNA, proteins and lipids from cell to cell. Notably, in the immune system, they have protective functions. However in cancer, exosomes acquire new, immunosuppressive properties that cause the dysregulation of immune cells and immune escape of tumor cells supporting cancer progression and metastasis. Therefore, current investigations focus on the regulation of exosome levels for immunotherapeutic interventions. In this review, we discuss the role of exosomes in immunomodulation of lymphoid and myeloid cells, and their use as immune stimulatory agents to elicit specific cytotoxic responses against the tumor.

AB - Exosomes, small extracellular vesicles mediate intercellular communication by transferring their cargo including DNA, RNA, proteins and lipids from cell to cell. Notably, in the immune system, they have protective functions. However in cancer, exosomes acquire new, immunosuppressive properties that cause the dysregulation of immune cells and immune escape of tumor cells supporting cancer progression and metastasis. Therefore, current investigations focus on the regulation of exosome levels for immunotherapeutic interventions. In this review, we discuss the role of exosomes in immunomodulation of lymphoid and myeloid cells, and their use as immune stimulatory agents to elicit specific cytotoxic responses against the tumor.

U2 - 10.3390/ncrna7010004

DO - 10.3390/ncrna7010004

M3 - SCORING: Review article

C2 - 33435564

VL - 7

JO - NON-CODING RNA

JF - NON-CODING RNA

SN - 2311-553X

IS - 1

M1 - 4

ER -