Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS)

Standard

Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS). / Probst, Pascal; Hüttner, Felix J; Meydan, Ömer; Abu Hilal, Mohammed; Adham, Mustapha; Barreto, Savio G; Besselink, Marc G; Busch, Olivier R; Bockhorn, Maximillian; Del Chiaro, Marco; Conlon, Kevin; Castillo, Carlos Fernandez-Del; Friess, Helmut; Fusai, Giuseppe Kito; Gianotti, Luca; Hackert, Thilo; Halloran, Christopher; Izbicki, Jakob; Kalkum, Eva; Kelemen, Dezső; Kenngott, Hannes G; Kretschmer, Rüdiger; Landré, Vincent; Lillemoe, Keith D; Miao, Yi; Marchegiani, Giovanni; Mihaljevic, André; Radenkovic, Dejan; Salvia, Roberto; Sandini, Marta; Serrablo, Alejandro; Shrikhande, Shailesh; Shukla, Parul J; Siriwardena, Ajith K; Strobel, Oliver; Uzunoglu, Faik G; Vollmer, Charles; Weitz, Jürgen; Wolfgang, Christopher L; Zerbi, Alessandro; Bassi, Claudio; Dervenis, Christos; Neoptolemos, John; Büchler, Markus W; Diener, Markus K.

in: SURGERY, Jahrgang 170, Nr. 5, 11.2021, S. 1517-1524.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Probst, P, Hüttner, FJ, Meydan, Ö, Abu Hilal, M, Adham, M, Barreto, SG, Besselink, MG, Busch, OR, Bockhorn, M, Del Chiaro, M, Conlon, K, Castillo, CF-D, Friess, H, Fusai, GK, Gianotti, L, Hackert, T, Halloran, C, Izbicki, J, Kalkum, E, Kelemen, D, Kenngott, HG, Kretschmer, R, Landré, V, Lillemoe, KD, Miao, Y, Marchegiani, G, Mihaljevic, A, Radenkovic, D, Salvia, R, Sandini, M, Serrablo, A, Shrikhande, S, Shukla, PJ, Siriwardena, AK, Strobel, O, Uzunoglu, FG, Vollmer, C, Weitz, J, Wolfgang, CL, Zerbi, A, Bassi, C, Dervenis, C, Neoptolemos, J, Büchler, MW & Diener, MK 2021, 'Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS)', SURGERY, Jg. 170, Nr. 5, S. 1517-1524. https://doi.org/10.1016/j.surg.2021.04.023

APA

Probst, P., Hüttner, F. J., Meydan, Ö., Abu Hilal, M., Adham, M., Barreto, S. G., Besselink, M. G., Busch, O. R., Bockhorn, M., Del Chiaro, M., Conlon, K., Castillo, C. F-D., Friess, H., Fusai, G. K., Gianotti, L., Hackert, T., Halloran, C., Izbicki, J., Kalkum, E., ... Diener, M. K. (2021). Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS). SURGERY, 170(5), 1517-1524. https://doi.org/10.1016/j.surg.2021.04.023

Vancouver

Bibtex

@article{4d99bf75eb3944afb2f2d081cbf2f9d6,
title = "Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS)",
abstract = "BACKGROUND: Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery.METHODS: PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all randomized controlled trials and systematic reviews on pancreatic surgery. Outcomes from every existing randomized controlled trial were extracted, and trial quality was assessed. Systematic reviews were used to identify an absence of randomized controlled trials. Randomized controlled trials and systematic reviews on identical subjects were grouped according to research topics. A web-based evidence map modeled after a mind map was created to visualize existing evidence. Meta-analyses of specific outcomes of pancreatic surgery were performed for all research topics with more than 3 randomized controlled trials. For partial pancreatoduodenectomy and distal pancreatectomy, pooled benchmarks for outcomes were calculated with a 99% confidence interval. The evidence map undergoes regular updates.RESULTS: Out of 30,860 articles reviewed, 328 randomized controlled trials on 35,600 patients and 332 systematic reviews were included and grouped into 76 research topics. Most randomized controlled trials were from Europe (46%) and most systematic reviews were from Asia (51%). A living meta-analysis of 21 out of 76 research topics (28%) was performed and included in the web-based evidence map. Evidence gaps were identified in 11 out of 76 research topics (14%). The benchmark for mortality was 2% (99% confidence interval: 1%-2%) for partial pancreatoduodenectomy and <1% (99% confidence interval: 0%-1%) for distal pancreatectomy. The benchmark for overall complications was 53% (99%confidence interval: 46%-61%) for partial pancreatoduodenectomy and 59% (99% confidence interval: 44%-80%) for distal pancreatectomy.CONCLUSION: The International Study Group of Pancreatic Surgery Evidence Map of Pancreatic Surgery, which is freely accessible via www.evidencemap.surgery and as a mobile phone app, provides a regularly updated overview of the available literature displayed in an intuitive fashion. Clinical decision making and evidence-based patient information are supported by the primary data provided, as well as by living meta-analyses. Researchers can use the systematic literature search and processed data for their own projects, and funding bodies can base their research priorities on evidence gaps that the map uncovers.",
author = "Pascal Probst and H{\"u}ttner, {Felix J} and {\"O}mer Meydan and {Abu Hilal}, Mohammed and Mustapha Adham and Barreto, {Savio G} and Besselink, {Marc G} and Busch, {Olivier R} and Maximillian Bockhorn and {Del Chiaro}, Marco and Kevin Conlon and Castillo, {Carlos Fernandez-Del} and Helmut Friess and Fusai, {Giuseppe Kito} and Luca Gianotti and Thilo Hackert and Christopher Halloran and Jakob Izbicki and Eva Kalkum and Dezs{\H o} Kelemen and Kenngott, {Hannes G} and R{\"u}diger Kretschmer and Vincent Landr{\'e} and Lillemoe, {Keith D} and Yi Miao and Giovanni Marchegiani and Andr{\'e} Mihaljevic and Dejan Radenkovic and Roberto Salvia and Marta Sandini and Alejandro Serrablo and Shailesh Shrikhande and Shukla, {Parul J} and Siriwardena, {Ajith K} and Oliver Strobel and Uzunoglu, {Faik G} and Charles Vollmer and J{\"u}rgen Weitz and Wolfgang, {Christopher L} and Alessandro Zerbi and Claudio Bassi and Christos Dervenis and John Neoptolemos and B{\"u}chler, {Markus W} and Diener, {Markus K}",
note = "Copyright {\textcopyright} 2021 The Authors. Published by Elsevier Inc. All rights reserved.",
year = "2021",
month = nov,
doi = "10.1016/j.surg.2021.04.023",
language = "English",
volume = "170",
pages = "1517--1524",
journal = "SURGERY",
issn = "0039-6060",
publisher = "Mosby Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Evidence Map of Pancreatic Surgery-A living systematic review with meta-analyses by the International Study Group of Pancreatic Surgery (ISGPS)

AU - Probst, Pascal

AU - Hüttner, Felix J

AU - Meydan, Ömer

AU - Abu Hilal, Mohammed

AU - Adham, Mustapha

AU - Barreto, Savio G

AU - Besselink, Marc G

AU - Busch, Olivier R

AU - Bockhorn, Maximillian

AU - Del Chiaro, Marco

AU - Conlon, Kevin

AU - Castillo, Carlos Fernandez-Del

AU - Friess, Helmut

AU - Fusai, Giuseppe Kito

AU - Gianotti, Luca

AU - Hackert, Thilo

AU - Halloran, Christopher

AU - Izbicki, Jakob

AU - Kalkum, Eva

AU - Kelemen, Dezső

AU - Kenngott, Hannes G

AU - Kretschmer, Rüdiger

AU - Landré, Vincent

AU - Lillemoe, Keith D

AU - Miao, Yi

AU - Marchegiani, Giovanni

AU - Mihaljevic, André

AU - Radenkovic, Dejan

AU - Salvia, Roberto

AU - Sandini, Marta

AU - Serrablo, Alejandro

AU - Shrikhande, Shailesh

AU - Shukla, Parul J

AU - Siriwardena, Ajith K

AU - Strobel, Oliver

AU - Uzunoglu, Faik G

AU - Vollmer, Charles

AU - Weitz, Jürgen

AU - Wolfgang, Christopher L

AU - Zerbi, Alessandro

AU - Bassi, Claudio

AU - Dervenis, Christos

AU - Neoptolemos, John

AU - Büchler, Markus W

AU - Diener, Markus K

N1 - Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

PY - 2021/11

Y1 - 2021/11

N2 - BACKGROUND: Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery.METHODS: PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all randomized controlled trials and systematic reviews on pancreatic surgery. Outcomes from every existing randomized controlled trial were extracted, and trial quality was assessed. Systematic reviews were used to identify an absence of randomized controlled trials. Randomized controlled trials and systematic reviews on identical subjects were grouped according to research topics. A web-based evidence map modeled after a mind map was created to visualize existing evidence. Meta-analyses of specific outcomes of pancreatic surgery were performed for all research topics with more than 3 randomized controlled trials. For partial pancreatoduodenectomy and distal pancreatectomy, pooled benchmarks for outcomes were calculated with a 99% confidence interval. The evidence map undergoes regular updates.RESULTS: Out of 30,860 articles reviewed, 328 randomized controlled trials on 35,600 patients and 332 systematic reviews were included and grouped into 76 research topics. Most randomized controlled trials were from Europe (46%) and most systematic reviews were from Asia (51%). A living meta-analysis of 21 out of 76 research topics (28%) was performed and included in the web-based evidence map. Evidence gaps were identified in 11 out of 76 research topics (14%). The benchmark for mortality was 2% (99% confidence interval: 1%-2%) for partial pancreatoduodenectomy and <1% (99% confidence interval: 0%-1%) for distal pancreatectomy. The benchmark for overall complications was 53% (99%confidence interval: 46%-61%) for partial pancreatoduodenectomy and 59% (99% confidence interval: 44%-80%) for distal pancreatectomy.CONCLUSION: The International Study Group of Pancreatic Surgery Evidence Map of Pancreatic Surgery, which is freely accessible via www.evidencemap.surgery and as a mobile phone app, provides a regularly updated overview of the available literature displayed in an intuitive fashion. Clinical decision making and evidence-based patient information are supported by the primary data provided, as well as by living meta-analyses. Researchers can use the systematic literature search and processed data for their own projects, and funding bodies can base their research priorities on evidence gaps that the map uncovers.

AB - BACKGROUND: Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery.METHODS: PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all randomized controlled trials and systematic reviews on pancreatic surgery. Outcomes from every existing randomized controlled trial were extracted, and trial quality was assessed. Systematic reviews were used to identify an absence of randomized controlled trials. Randomized controlled trials and systematic reviews on identical subjects were grouped according to research topics. A web-based evidence map modeled after a mind map was created to visualize existing evidence. Meta-analyses of specific outcomes of pancreatic surgery were performed for all research topics with more than 3 randomized controlled trials. For partial pancreatoduodenectomy and distal pancreatectomy, pooled benchmarks for outcomes were calculated with a 99% confidence interval. The evidence map undergoes regular updates.RESULTS: Out of 30,860 articles reviewed, 328 randomized controlled trials on 35,600 patients and 332 systematic reviews were included and grouped into 76 research topics. Most randomized controlled trials were from Europe (46%) and most systematic reviews were from Asia (51%). A living meta-analysis of 21 out of 76 research topics (28%) was performed and included in the web-based evidence map. Evidence gaps were identified in 11 out of 76 research topics (14%). The benchmark for mortality was 2% (99% confidence interval: 1%-2%) for partial pancreatoduodenectomy and <1% (99% confidence interval: 0%-1%) for distal pancreatectomy. The benchmark for overall complications was 53% (99%confidence interval: 46%-61%) for partial pancreatoduodenectomy and 59% (99% confidence interval: 44%-80%) for distal pancreatectomy.CONCLUSION: The International Study Group of Pancreatic Surgery Evidence Map of Pancreatic Surgery, which is freely accessible via www.evidencemap.surgery and as a mobile phone app, provides a regularly updated overview of the available literature displayed in an intuitive fashion. Clinical decision making and evidence-based patient information are supported by the primary data provided, as well as by living meta-analyses. Researchers can use the systematic literature search and processed data for their own projects, and funding bodies can base their research priorities on evidence gaps that the map uncovers.

U2 - 10.1016/j.surg.2021.04.023

DO - 10.1016/j.surg.2021.04.023

M3 - SCORING: Journal article

C2 - 34187695

VL - 170

SP - 1517

EP - 1524

JO - SURGERY

JF - SURGERY

SN - 0039-6060

IS - 5

ER -