Evaluation of post-mortem lateral cerebral ventricle changes using sequential scans during post-mortem computed tomography

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Evaluation of post-mortem lateral cerebral ventricle changes using sequential scans during post-mortem computed tomography. / Hasegawa, Iwao; Shimizu, Akinobu; Saito, Atsushi; Suzuki, Hideto; Vogel, Hermann; Püschel, Klaus; Heinemann, Axel.

in: INT J LEGAL MED, Jahrgang 130, Nr. 5, 09.2016, S. 1323-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{68255393c7f74fac88e7eabe8cc73b01,
title = "Evaluation of post-mortem lateral cerebral ventricle changes using sequential scans during post-mortem computed tomography",
abstract = "In the present study, we evaluated post-mortem lateral cerebral ventricle (LCV) changes using computed tomography (CT). Subsequent periodical CT scans termed {"}sequential scans{"} were obtained for three cadavers. The first scan was performed immediately after the body was transferred from the emergency room to the institute of legal medicine. Sequential scans were obtained and evaluated for 24 h at maximum. The time of death had been determined in the emergency room. The sequential scans enabled us to observe periodical post-mortem changes in CT images. The series of continuous LCV images obtained up to 24 h (two cases)/16 h (1 case) after death was evaluated. The average Hounsfield units (HU) within the LCVs progressively increased, and LCV volume progressively decreased over time. The HU in the cerebrospinal fluid (CSF) increased at an individual rate proportional to the post-mortem interval (PMI). Thus, an early longitudinal radiodensity change in the CSF could be potential indicator of post-mortem interval (PMI). Sequential imaging scans reveal post-mortem changes in the CSF space which may reflect post-mortem brain alterations. Further studies are needed to evaluate the proposed CSF change markers in correlation with other validated PMI indicators.",
keywords = "Journal Article",
author = "Iwao Hasegawa and Akinobu Shimizu and Atsushi Saito and Hideto Suzuki and Hermann Vogel and Klaus P{\"u}schel and Axel Heinemann",
year = "2016",
month = sep,
doi = "10.1007/s00414-016-1327-2",
language = "English",
volume = "130",
pages = "1323--8",
journal = "INT J LEGAL MED",
issn = "0937-9827",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - Evaluation of post-mortem lateral cerebral ventricle changes using sequential scans during post-mortem computed tomography

AU - Hasegawa, Iwao

AU - Shimizu, Akinobu

AU - Saito, Atsushi

AU - Suzuki, Hideto

AU - Vogel, Hermann

AU - Püschel, Klaus

AU - Heinemann, Axel

PY - 2016/9

Y1 - 2016/9

N2 - In the present study, we evaluated post-mortem lateral cerebral ventricle (LCV) changes using computed tomography (CT). Subsequent periodical CT scans termed "sequential scans" were obtained for three cadavers. The first scan was performed immediately after the body was transferred from the emergency room to the institute of legal medicine. Sequential scans were obtained and evaluated for 24 h at maximum. The time of death had been determined in the emergency room. The sequential scans enabled us to observe periodical post-mortem changes in CT images. The series of continuous LCV images obtained up to 24 h (two cases)/16 h (1 case) after death was evaluated. The average Hounsfield units (HU) within the LCVs progressively increased, and LCV volume progressively decreased over time. The HU in the cerebrospinal fluid (CSF) increased at an individual rate proportional to the post-mortem interval (PMI). Thus, an early longitudinal radiodensity change in the CSF could be potential indicator of post-mortem interval (PMI). Sequential imaging scans reveal post-mortem changes in the CSF space which may reflect post-mortem brain alterations. Further studies are needed to evaluate the proposed CSF change markers in correlation with other validated PMI indicators.

AB - In the present study, we evaluated post-mortem lateral cerebral ventricle (LCV) changes using computed tomography (CT). Subsequent periodical CT scans termed "sequential scans" were obtained for three cadavers. The first scan was performed immediately after the body was transferred from the emergency room to the institute of legal medicine. Sequential scans were obtained and evaluated for 24 h at maximum. The time of death had been determined in the emergency room. The sequential scans enabled us to observe periodical post-mortem changes in CT images. The series of continuous LCV images obtained up to 24 h (two cases)/16 h (1 case) after death was evaluated. The average Hounsfield units (HU) within the LCVs progressively increased, and LCV volume progressively decreased over time. The HU in the cerebrospinal fluid (CSF) increased at an individual rate proportional to the post-mortem interval (PMI). Thus, an early longitudinal radiodensity change in the CSF could be potential indicator of post-mortem interval (PMI). Sequential imaging scans reveal post-mortem changes in the CSF space which may reflect post-mortem brain alterations. Further studies are needed to evaluate the proposed CSF change markers in correlation with other validated PMI indicators.

KW - Journal Article

U2 - 10.1007/s00414-016-1327-2

DO - 10.1007/s00414-016-1327-2

M3 - SCORING: Journal article

C2 - 27048214

VL - 130

SP - 1323

EP - 1328

JO - INT J LEGAL MED

JF - INT J LEGAL MED

SN - 0937-9827

IS - 5

ER -