Evaluation of a short instrument for measuring health-related quality of life in oncological patients in routine care (HELP-6): an observational study
Beteiligte Einrichtungen
- Institut und Poliklinik für Medizinische Psychologie
- Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde
- II. Medizinische Klinik und Poliklinik
- Interdisziplinäre Klinik und Poliklinik für Stammzelltransplantation
- Klinik und Poliklinik für Gynäkologie
- Klinik und Poliklinik für Strahlentherapie und Radioonkologie
Abstract
Methods: This observational study with a repeated measurements design included oncological inpatients and outpatients. A total of 630 patients participated at the first point of measurement and 404 at the second point of measurement. To evaluate the instrument, we conducted hierarchical confirmative factor analyses and for further validation correlated the resulting factors with standardized and validated HrQoL measurements. Test–retest reliability and responsiveness to change were tested.
Results: The developed questionnaire “HELP-6” (“Hamburg Inventory for Measuring Quality of Life in Oncological Patients”) has a six-factor structure and has moderate-to-good convergent validity (r= −0.25 –−0.68). Test–retest reliability was moderate-to-good (r =0.56−0.81, p < 0.001). Indications for responsiveness to change were found for three dimensions. The final version of the questionnaire HELP-6 has six dimensions with one item each.
Conclusion: With the HELP-6 instrument for measuring HrQoL in cancer patients, we provide a short and practical patient-reported outcome instrument. Though responsiveness to change could not be confirmed for all dimensions in this study, the HELP-6 includes time-efficient completion and evaluation and is informative in relevant HrQoL dimensions of cancer patients. Therefore, the HELP-6 poses an important addition to inpatient and outpatient routine cancer care.
Bibliografische Daten
Originalsprache | Englisch |
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ISSN | 1664-1078 |
DOIs | |
Status | Veröffentlicht - 2023 |
Anmerkungen des Dekanats
Copyright © 2023 Schrage, Görlach, Betz, Bokemeyer, Kröger, Mueller, Krüll, Schulz and Bleich.
PubMed | 37260965 |
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