European results of neutron therapy in soft tissue sarcomas.
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European results of neutron therapy in soft tissue sarcomas. / Schwarz, R; Krüll, Andreas; Lessel, A; Engenhart-Cabillic, R; Favre, A; Prott, F J; Auberger, T; Schmidt, R.
in: Recent Results Cancer Res, Jahrgang 150, 1998, S. 100-112.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - European results of neutron therapy in soft tissue sarcomas.
AU - Schwarz, R
AU - Krüll, Andreas
AU - Lessel, A
AU - Engenhart-Cabillic, R
AU - Favre, A
AU - Prott, F J
AU - Auberger, T
AU - Schmidt, R
PY - 1998
Y1 - 1998
N2 - The purpose of this publication is to review the data of European neutron therapy facilities in the treatment of soft tissue sarcoma. In the past locally advanced soft tissue sarcoma was a common indication for neutron therapy in several European centers. Data from 1171 patients treated at 11 centers were analysed on the basis of published data or personal communication. Neutron therapy was of benefit especially for patients with primary radiotherapy of inoperable tumors, and with macroscopic disease after surgery. Local control was about 50% in these patients. These results are superior to those from photon therapy from the literature. Results for postoperative neutron therapy after R0- and R1-resection are similar to those from photon therapy. The incidence of late side effects was considerably high in some neutron series. This is influenced by the treatment of most patients with first-generation machines of limited technical standard, and that in most cases large treatment volumes were irradiated.
AB - The purpose of this publication is to review the data of European neutron therapy facilities in the treatment of soft tissue sarcoma. In the past locally advanced soft tissue sarcoma was a common indication for neutron therapy in several European centers. Data from 1171 patients treated at 11 centers were analysed on the basis of published data or personal communication. Neutron therapy was of benefit especially for patients with primary radiotherapy of inoperable tumors, and with macroscopic disease after surgery. Local control was about 50% in these patients. These results are superior to those from photon therapy from the literature. Results for postoperative neutron therapy after R0- and R1-resection are similar to those from photon therapy. The incidence of late side effects was considerably high in some neutron series. This is influenced by the treatment of most patients with first-generation machines of limited technical standard, and that in most cases large treatment volumes were irradiated.
KW - Humans
KW - Survival Rate
KW - Neutrons/therapeutic use
KW - Sarcoma/mortality/pathology/radiotherapy
KW - Humans
KW - Survival Rate
KW - Neutrons/therapeutic use
KW - Sarcoma/mortality/pathology/radiotherapy
M3 - SCORING: Journal article
VL - 150
SP - 100
EP - 112
JO - Recent Results Cancer Res
JF - Recent Results Cancer Res
SN - 0080-0015
ER -
