ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
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ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. / Minner, Sarah Jane Pauline; Enodien, Malaika; Sirma, Hüseyin; Lübke, Andreas; Krohn, Antje; Mayer, Pascale S; Simon, Ronald; Tennstedt, Pierre; Müller, Julia; Scholz, Laura; Brase, Jan C; Liu, Alvin Y; Schlüter, Hartmut; Pantel, Klaus; Schumacher, Udo; Bokemeyer, Carsten; Steuber, Thomas; Graefen, Markus; Sauter, Guido; Schlomm, Thorsten.
in: CLIN CANCER RES, Jahrgang 17, Nr. 18, 18, 2011, S. 5878-5888.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
AU - Minner, Sarah Jane Pauline
AU - Enodien, Malaika
AU - Sirma, Hüseyin
AU - Lübke, Andreas
AU - Krohn, Antje
AU - Mayer, Pascale S
AU - Simon, Ronald
AU - Tennstedt, Pierre
AU - Müller, Julia
AU - Scholz, Laura
AU - Brase, Jan C
AU - Liu, Alvin Y
AU - Schlüter, Hartmut
AU - Pantel, Klaus
AU - Schumacher, Udo
AU - Bokemeyer, Carsten
AU - Steuber, Thomas
AU - Graefen, Markus
AU - Sauter, Guido
AU - Schlomm, Thorsten
PY - 2011
Y1 - 2011
N2 - About 50% of prostate cancers have TMPRSS2-ERG fusions with concurrent ERG overexpression. The aim of this study was to determine whether clinical differences exist between ERG-positive and ERG-negative cancers in surgically treated patients not exposed to antihormonal therapy. A secondary aim was to search for differences between these tumor classes.
AB - About 50% of prostate cancers have TMPRSS2-ERG fusions with concurrent ERG overexpression. The aim of this study was to determine whether clinical differences exist between ERG-positive and ERG-negative cancers in surgically treated patients not exposed to antihormonal therapy. A secondary aim was to search for differences between these tumor classes.
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Aged, 80 and over
KW - Cell Line, Tumor
KW - Gene Expression Regulation, Neoplastic
KW - Gene Expression Profiling
KW - Gene Rearrangement
KW - Neoplasm Recurrence, Local/diagnosis
KW - Prostate-Specific Antigen/blood
KW - Prostatectomy
KW - Prostatic Neoplasms/diagnosis/genetics/metabolism/surgery
KW - Receptors, Androgen/metabolism
KW - Trans-Activators/genetics/metabolism
KW - Tumor Markers, Biological/genetics/metabolism
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Aged, 80 and over
KW - Cell Line, Tumor
KW - Gene Expression Regulation, Neoplastic
KW - Gene Expression Profiling
KW - Gene Rearrangement
KW - Neoplasm Recurrence, Local/diagnosis
KW - Prostate-Specific Antigen/blood
KW - Prostatectomy
KW - Prostatic Neoplasms/diagnosis/genetics/metabolism/surgery
KW - Receptors, Androgen/metabolism
KW - Trans-Activators/genetics/metabolism
KW - Tumor Markers, Biological/genetics/metabolism
M3 - SCORING: Journal article
VL - 17
SP - 5878
EP - 5888
JO - CLIN CANCER RES
JF - CLIN CANCER RES
SN - 1078-0432
IS - 18
M1 - 18
ER -