Eremophilane-type glucosides from the leaves of Ligularia calthifolia Maxim:Critical Assessment of Small Molecules Identification 2016

Three eremophilane-type glucosides (1–3) along with three known congeners alticolosides A, B and D (4–6) have been isolated from the leaves of Ligularia calthifolia Maxim. (Asteraceae). The structures of 1–3 have been elucidated by spectroscopic analysis as well as by chemical transformations. A distinctive feature of the compounds 1–3 is the presence of an acetyl group in the glucose residues. The compounds were non-cytotoxic against human normal prostate cells as well as prostate cancer cells.