PortalPublikationenEluting antibiotic bone graft substitutes for the treatment ...

Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use?

Standard

Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use? / Schlickewei, C.W.; Yarar, S.; Rueger, J.M.

in: ORTHOP RES REV, Jahrgang 114, 2014, S. 71—79.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Schlickewei, CW, Yarar, S & Rueger, JM 2014, 'Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use?', ORTHOP RES REV, Jg. 114, S. 71—79. https://doi.org/10.2147/ORR.S44747

APA

Schlickewei, C. W., Yarar, S., & Rueger, J. M. (2014). Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use? ORTHOP RES REV, 114, 71—79. https://doi.org/10.2147/ORR.S44747

Vancouver

Schlickewei CW, Yarar S, Rueger JM. Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use? ORTHOP RES REV. 2014;114:71—79. https://doi.org/10.2147/ORR.S44747

Bibtex

@article{9c712f4007594661b2497f1445c0b701,
title = "Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use?",
abstract = "Despite continuous advances in surgical procedures and antibiotic therapies, osteomyelitis still remains one of the most devastating complications in trauma and orthopedic surgery. Treatment of osteomyelitis represents a severe and challenging problem, even if the treatment of acute cases with systemic antibiotics has good success rates. Chronic cases need a consequent resection of dead or infected bone in addition to an improved systemic and local antibiotic therapy. The gold standard therapy is the implantation of polymethylmethacrylate as spacer and local antibiotic carrier. Besides other drawbacks, nonbiodegradable polymethylmethacrylate implants need to be removed. This led to an ongoing search for a biodegradable antibiotic bone graft substitute for the treatment of osteomyelitis to avoid secondary removal. The number of clinically available products grows, but still, the available number of peer-reviewed clinical trials to prove their efficiency is limited. This review gives an overview of the current available literature.",
author = "C.W. Schlickewei and S. Yarar and J.M. Rueger",
year = "2014",
doi = "10.2147/ORR.S44747",
language = "English",
volume = "114",
pages = "71—79",
journal = "ORTHOP RES REV",
issn = "1179-1462",
publisher = "DOVE MEDICAL PRESS LTD",

}

RIS

TY - JOUR

T1 - Eluting antibiotic bone graft substitutes for the treatment of osteomyelitis in long bones. A review: Evidence for their use?

AU - Schlickewei, C.W.

AU - Yarar, S.

AU - Rueger, J.M.

PY - 2014

Y1 - 2014

N2 - Despite continuous advances in surgical procedures and antibiotic therapies, osteomyelitis still remains one of the most devastating complications in trauma and orthopedic surgery. Treatment of osteomyelitis represents a severe and challenging problem, even if the treatment of acute cases with systemic antibiotics has good success rates. Chronic cases need a consequent resection of dead or infected bone in addition to an improved systemic and local antibiotic therapy. The gold standard therapy is the implantation of polymethylmethacrylate as spacer and local antibiotic carrier. Besides other drawbacks, nonbiodegradable polymethylmethacrylate implants need to be removed. This led to an ongoing search for a biodegradable antibiotic bone graft substitute for the treatment of osteomyelitis to avoid secondary removal. The number of clinically available products grows, but still, the available number of peer-reviewed clinical trials to prove their efficiency is limited. This review gives an overview of the current available literature.

AB - Despite continuous advances in surgical procedures and antibiotic therapies, osteomyelitis still remains one of the most devastating complications in trauma and orthopedic surgery. Treatment of osteomyelitis represents a severe and challenging problem, even if the treatment of acute cases with systemic antibiotics has good success rates. Chronic cases need a consequent resection of dead or infected bone in addition to an improved systemic and local antibiotic therapy. The gold standard therapy is the implantation of polymethylmethacrylate as spacer and local antibiotic carrier. Besides other drawbacks, nonbiodegradable polymethylmethacrylate implants need to be removed. This led to an ongoing search for a biodegradable antibiotic bone graft substitute for the treatment of osteomyelitis to avoid secondary removal. The number of clinically available products grows, but still, the available number of peer-reviewed clinical trials to prove their efficiency is limited. This review gives an overview of the current available literature.

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84947571919&partnerID=MN8TOARS

U2 - 10.2147/ORR.S44747

DO - 10.2147/ORR.S44747

M3 - SCORING: Review article

VL - 114

SP - 71—79

JO - ORTHOP RES REV

JF - ORTHOP RES REV

SN - 1179-1462

ER -