Elevated pretreatment serum concentration of YKL-40-An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer.
Beteiligte Einrichtungen
Abstract
The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several cancer types. However, the role of YKL-40 has not been established in nonsmall cell lung cancer (NSCLC).
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 17 |
| ISSN | 0008-543X |
| Status | Veröffentlicht - 2010 |
| pubmed | 20564116 |
|---|
