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Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China

Standard

Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China. / Jia, Man; Kluwe, Lan; Liu, Hui-Cong; Tang, Qian-Jue; Liu, Lian; Wang, Zhen-Zhen; Tian, Li-Xia; Zhao, Li; Chen, Ying-Chao; Friedrich, Reinhard E; Sun, Zhuo-Jun; Xu, Lian-Wei.

in: IN VIVO, Jahrgang 29, Nr. 1, 21.01.2015, S. 109-15.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Jia, M, Kluwe, L, Liu, H-C, Tang, Q-J, Liu, L, Wang, Z-Z, Tian, L-X, Zhao, L, Chen, Y-C, Friedrich, RE, Sun, Z-J & Xu, L-W 2015, 'Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China', IN VIVO, Jg. 29, Nr. 1, S. 109-15.

APA

Jia, M., Kluwe, L., Liu, H-C., Tang, Q-J., Liu, L., Wang, Z-Z., Tian, L-X., Zhao, L., Chen, Y-C., Friedrich, R. E., Sun, Z-J., & Xu, L-W. (2015). Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China. IN VIVO, 29(1), 109-15.

Vancouver

Jia M, Kluwe L, Liu H-C, Tang Q-J, Liu L, Wang Z-Z et al. Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China. IN VIVO. 2015 Jan 21;29(1):109-15.

Bibtex

@article{80ac185d391e4d52a5426ea00b5b8e19,
title = "Efficacy and side-effects of a semi-individualized Chinese herb mixture {"}Ti{\'a}o Gēng Tāng{"} for menopausal syndrome in China",
abstract = "BACKGROUND: Chinese herbal medicine is an alternative therapy for menopausal problems and is widely practiced in China and many other Asian countries. However, efficacies and side-effects are rarely assessed according to the standards of evidence-based medicine.PATIENTS AND METHODS: This is a prospective observatory study following efficacy and side-effects of a semi-individualized Chinese herbal mixture {"}Ti{\'a}o Gēng Tāng (TGT){"} in 30 patients for 3 months. Another group of 30 patients receiving hormone therapy with tibolone was included as a positive comparison. Common questionnaire-based measuring instruments were: modified Kupperman index, menopause rating scale, life quality and Chinese medical symptom scale (CMSS). Follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were determined before and three months after the treatments.RESULTS: Significant improvement was seen in overall scores of all the four measurements in both groups. For some symptoms, including dry mouth, tinnitus, poor appetite and constipation, TGT was more effective than tibolone. For psychosocial and sexual sub-scales of life quality, tibolone has a slightly higher remedy rate than TGT. TGT lowered FSH and LH significantly, as tibolone did, but elevated E2 significantly less than tibolone. Various adverse events, including body weight increase, abdomen discomfort, nausea/vomiting, emotional instability, pressure in breasts and dizziness, were reported by patients treated with tibolone, whereas only diarrhea was observed in two patients treated with TGT.CONCLUSION: TGT alleviates menopausal symptoms with similar efficacy as tibolone but has fewer side effects.",
author = "Man Jia and Lan Kluwe and Hui-Cong Liu and Qian-Jue Tang and Lian Liu and Zhen-Zhen Wang and Li-Xia Tian and Li Zhao and Ying-Chao Chen and Friedrich, {Reinhard E} and Zhuo-Jun Sun and Lian-Wei Xu",
note = "Copyright {\textcopyright} 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.",
year = "2015",
month = jan,
day = "21",
language = "English",
volume = "29",
pages = "109--15",
journal = "IN VIVO",
issn = "0258-851X",
publisher = "International Institute of Anticancer Research",
number = "1",

}

RIS

TY - JOUR

T1 - Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China

AU - Jia, Man

AU - Kluwe, Lan

AU - Liu, Hui-Cong

AU - Tang, Qian-Jue

AU - Liu, Lian

AU - Wang, Zhen-Zhen

AU - Tian, Li-Xia

AU - Zhao, Li

AU - Chen, Ying-Chao

AU - Friedrich, Reinhard E

AU - Sun, Zhuo-Jun

AU - Xu, Lian-Wei

N1 - Copyright © 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

PY - 2015/1/21

Y1 - 2015/1/21

N2 - BACKGROUND: Chinese herbal medicine is an alternative therapy for menopausal problems and is widely practiced in China and many other Asian countries. However, efficacies and side-effects are rarely assessed according to the standards of evidence-based medicine.PATIENTS AND METHODS: This is a prospective observatory study following efficacy and side-effects of a semi-individualized Chinese herbal mixture "Tiáo Gēng Tāng (TGT)" in 30 patients for 3 months. Another group of 30 patients receiving hormone therapy with tibolone was included as a positive comparison. Common questionnaire-based measuring instruments were: modified Kupperman index, menopause rating scale, life quality and Chinese medical symptom scale (CMSS). Follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were determined before and three months after the treatments.RESULTS: Significant improvement was seen in overall scores of all the four measurements in both groups. For some symptoms, including dry mouth, tinnitus, poor appetite and constipation, TGT was more effective than tibolone. For psychosocial and sexual sub-scales of life quality, tibolone has a slightly higher remedy rate than TGT. TGT lowered FSH and LH significantly, as tibolone did, but elevated E2 significantly less than tibolone. Various adverse events, including body weight increase, abdomen discomfort, nausea/vomiting, emotional instability, pressure in breasts and dizziness, were reported by patients treated with tibolone, whereas only diarrhea was observed in two patients treated with TGT.CONCLUSION: TGT alleviates menopausal symptoms with similar efficacy as tibolone but has fewer side effects.

AB - BACKGROUND: Chinese herbal medicine is an alternative therapy for menopausal problems and is widely practiced in China and many other Asian countries. However, efficacies and side-effects are rarely assessed according to the standards of evidence-based medicine.PATIENTS AND METHODS: This is a prospective observatory study following efficacy and side-effects of a semi-individualized Chinese herbal mixture "Tiáo Gēng Tāng (TGT)" in 30 patients for 3 months. Another group of 30 patients receiving hormone therapy with tibolone was included as a positive comparison. Common questionnaire-based measuring instruments were: modified Kupperman index, menopause rating scale, life quality and Chinese medical symptom scale (CMSS). Follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were determined before and three months after the treatments.RESULTS: Significant improvement was seen in overall scores of all the four measurements in both groups. For some symptoms, including dry mouth, tinnitus, poor appetite and constipation, TGT was more effective than tibolone. For psychosocial and sexual sub-scales of life quality, tibolone has a slightly higher remedy rate than TGT. TGT lowered FSH and LH significantly, as tibolone did, but elevated E2 significantly less than tibolone. Various adverse events, including body weight increase, abdomen discomfort, nausea/vomiting, emotional instability, pressure in breasts and dizziness, were reported by patients treated with tibolone, whereas only diarrhea was observed in two patients treated with TGT.CONCLUSION: TGT alleviates menopausal symptoms with similar efficacy as tibolone but has fewer side effects.

M3 - SCORING: Journal article

C2 - 25600538

VL - 29

SP - 109

EP - 115

JO - IN VIVO

JF - IN VIVO

SN - 0258-851X

IS - 1

ER -