Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol.

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Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol. / Kemper, Markus J.; Harps, E; Hellwege, H H; Müller-Wiefel, D E.

in: EUR J PEDIATR, Jahrgang 155, Nr. 6, 6, 1996, S. 495-497.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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Kemper MJ, Harps E, Hellwege HH, Müller-Wiefel DE. Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol. EUR J PEDIATR. 1996;155(6):495-497. 6.

Bibtex

@article{2f7453eacdcd44dd89c260afcd089da6,
title = "Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol.",
abstract = "Hyperkalaemia is a life-threatening emergency and infusion of glucose with insulin has so far been regarded as the standard treatment of choice. Recently the beta-2 stimulatory drug salbutamol has been shown to be an effective agent to treat hyperkalaemia by inducing a shift of potassium into the intracellular compartment. We treated 15 children aged 0.1-14 (mean 5.2) years suffering from acute hyperkalaemia (mean level 6.6 +/- 0.54, range 5.9-7.7 mmol/l) with a single infusion of salbutamol (5 micrograms/kg over 15 min). Serum potassium concentrations decreased significantly within 30 min to levels of 5.74 +/- 0.53 and 4.92 +/- 0.53 mmol/l after 120 min (P < 0.001, respectively). No side-effects occurred other than a light increase in heart rate in 3 patients.",
keywords = "Humans, Male, Female, Adolescent, Child, Combined Modality Therapy, Child, Preschool, Infant, Infant, Newborn, Drug Administration Schedule, Infusions, Intravenous, Renal Dialysis, Hyperkalemia/blood/*drug therapy/etiology, Potassium/blood, Adrenergic beta-Agonists/*administration & dosage, Albuterol/*administration & dosage, Peritoneal Dialysis, Humans, Male, Female, Adolescent, Child, Combined Modality Therapy, Child, Preschool, Infant, Infant, Newborn, Drug Administration Schedule, Infusions, Intravenous, Renal Dialysis, Hyperkalemia/blood/*drug therapy/etiology, Potassium/blood, Adrenergic beta-Agonists/*administration & dosage, Albuterol/*administration & dosage, Peritoneal Dialysis",
author = "Kemper, {Markus J.} and E Harps and Hellwege, {H H} and M{\"u}ller-Wiefel, {D E}",
year = "1996",
language = "English",
volume = "155",
pages = "495--497",
journal = "EUR J PEDIATR",
issn = "0340-6199",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol.

AU - Kemper, Markus J.

AU - Harps, E

AU - Hellwege, H H

AU - Müller-Wiefel, D E

PY - 1996

Y1 - 1996

N2 - Hyperkalaemia is a life-threatening emergency and infusion of glucose with insulin has so far been regarded as the standard treatment of choice. Recently the beta-2 stimulatory drug salbutamol has been shown to be an effective agent to treat hyperkalaemia by inducing a shift of potassium into the intracellular compartment. We treated 15 children aged 0.1-14 (mean 5.2) years suffering from acute hyperkalaemia (mean level 6.6 +/- 0.54, range 5.9-7.7 mmol/l) with a single infusion of salbutamol (5 micrograms/kg over 15 min). Serum potassium concentrations decreased significantly within 30 min to levels of 5.74 +/- 0.53 and 4.92 +/- 0.53 mmol/l after 120 min (P < 0.001, respectively). No side-effects occurred other than a light increase in heart rate in 3 patients.

AB - Hyperkalaemia is a life-threatening emergency and infusion of glucose with insulin has so far been regarded as the standard treatment of choice. Recently the beta-2 stimulatory drug salbutamol has been shown to be an effective agent to treat hyperkalaemia by inducing a shift of potassium into the intracellular compartment. We treated 15 children aged 0.1-14 (mean 5.2) years suffering from acute hyperkalaemia (mean level 6.6 +/- 0.54, range 5.9-7.7 mmol/l) with a single infusion of salbutamol (5 micrograms/kg over 15 min). Serum potassium concentrations decreased significantly within 30 min to levels of 5.74 +/- 0.53 and 4.92 +/- 0.53 mmol/l after 120 min (P < 0.001, respectively). No side-effects occurred other than a light increase in heart rate in 3 patients.

KW - Humans

KW - Male

KW - Female

KW - Adolescent

KW - Child

KW - Combined Modality Therapy

KW - Child, Preschool

KW - Infant

KW - Infant, Newborn

KW - Drug Administration Schedule

KW - Infusions, Intravenous

KW - Renal Dialysis

KW - Hyperkalemia/blood/drug therapy/etiology

KW - Potassium/blood

KW - Adrenergic beta-Agonists/administration & dosage

KW - Albuterol/administration & dosage

KW - Peritoneal Dialysis

KW - Humans

KW - Male

KW - Female

KW - Adolescent

KW - Child

KW - Combined Modality Therapy

KW - Child, Preschool

KW - Infant

KW - Infant, Newborn

KW - Drug Administration Schedule

KW - Infusions, Intravenous

KW - Renal Dialysis

KW - Hyperkalemia/blood/drug therapy/etiology

KW - Potassium/blood

KW - Adrenergic beta-Agonists/administration & dosage

KW - Albuterol/administration & dosage

KW - Peritoneal Dialysis

M3 - SCORING: Journal article

VL - 155

SP - 495

EP - 497

JO - EUR J PEDIATR

JF - EUR J PEDIATR

SN - 0340-6199

IS - 6

M1 - 6

ER -